Real‐time versus thermal desorption selected ion flow tube mass spectrometry for quantification of breath volatiles

Autor: Gudrun Koppen, Maarten Spruyt, Marc Raes, Jill Lindekens, Eddy Goelen, Gitte Slingers, Martin Vanden Eede

Publikováno v: Rapid communications in mass spectrometry

Rationale Selected ion flow tube mass spectrometry (SIFT-MS) is versatile, rapidly provides result output and determines a wide range of volatiles, making it suitable for biomedical applications. When direct sampling into the SIFT-MS instrument is im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4845c2da98b0fe2b99087322f884bef
https://doi.org/10.1002/rcm.8994

Diagnostic characterization of respiratory allergies by means of a multiplex immunoassay

Autor: Joline L.M. Millen, Gitte Slingers, Marc Raes, Ibbo Willems, Gudrun Koppen, Sabine A. S. Langie

Publikováno v: Clinical and Experimental Immunology
Clinical and Experimental Immunology, 203(2), 183-193. Wiley

The performance of the MSD immunoassay, as an allergy blood test, was compared to the skin prick test (SPT; golden standard in clinical practices) and ImmunoCAP™ assay (most commonly used blood test). The MSD immunoassay, detecting sIgE against res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae5f68ebc3cebd9306e92e2718d733d
https://doi.org/10.22541/au.159183067.72852643

Exhaled breath metabolomics reveals a pathogen-specific response in a rat pneumonia model for two human pathogenic bacteria: a proof-of-concept study

Autor: Gitte Slingers, Marc Raes, Joris J. T. H. Roelofs, Pouline M.P. van Oort, Stephen J. Fowler, Dennis C J J Bergmans, Ronny M. Schnabel, Royston Goodacre, Adrie Maas, Paul Brinkman, Lieuwe D. J. Bos, Gudrun Koppen, Marcus J. Schultz

Publikováno v: American journal of physiology. Lung cellular and molecular physiology
van Oort, P M, Brinkman, P, Slingers, G, Koppen, G, Maas, A, Roelofs, J J, Schnabel, R, Bergmans, D C, Raes, M, Goodacre, R, Fowler, S J, Schultz, M J, Bos, L D & BreathDx Consortium 2019, ' Exhaled breath metabolomics reveals a pathogen-specific response in a rat pneumonia model for two human pathogenic bacteria: A proof-of-concept study ', American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 316, no. 5, pp. L751-L756 . https://doi.org/10.1152/ajplung.00449.2018
American journal of physiology. Lung cellular and molecular physiology, 316(5), L751-L756. American Physiological Society
American Journal of Physiology-Lung Cellular and Molecular Physiology, 316(5), L751-L756. American Physiological Society

Volatile organic compounds in breath can reflect host and pathogen metabolism and might be used to diagnose pneumonia. We hypothesized that rats with Streptococcus pneumoniae ( SP) or Pseudomonas aeruginosa ( PA) pneumonia can be discriminated from u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeabbb5b50c934caf5df80e3be258d83
http://livrepository.liverpool.ac.uk/3077711/1/ajplung.00449.2018.pdf

Exhaled volatile markers analysed using Selected Ion Flow Tube Mass Spectrometry discriminate Pseudomonas aeruginosa and Streptococcus pneumoniae lung infection in a rat model study

Autor: Marcus J. Schultz, Philippe G. Jorens, Marc Raes, Gudrun Koppen, Joris J. T. H. Roelofs, Adrie Maas, Gitte Slingers, Pouline M.P. van Oort, Lieuwe D. J. Bos

Publikováno v: Respiratory infections.

Exhaled volatile organic compounds (VOCs) could potentially serve as non-invasive biomarkers for the diagnosis of respiratory infections. This study aims to discriminate rats infected with Pseudomonas aeruginosa (PA) or Streptococcus pneumoniae (SP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0a332b60b0b122c89a15d57325d7b83
https://doi.org/10.1183/13993003.congress-2018.pa2653