Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Gitte Moos, Knudsen"'
Autor:
Kamilla Woznica Miskowiak, Viktoria Damgaard, Johanna Mariegaard Schandorff, Julian Macoveanu, Gitte Moos Knudsen, Annette Johansen, Pontus Plaven-Sigray, Claus Svarer, Caroline Bruun Fussing, Katrine Cramer, Martin Balslev Jørgensen, Lars Vedel Kessing, Hannelore Ehrenreich
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Cognitive impairment is prevalent across neuropsychiatric disorders but there is a lack of treatment strategies with robust, enduring effects. Emerging evidence indicates that altitude-like hypoxia cognition training may induce lo
Externí odkaz:
https://doaj.org/article/a626539da28d4ef0a67f3810f3c6e4d5
Autor:
Sophia Armand, Christelle Langley, Annette Johansen, Brice Ozenne, Oliver Overgaard-Hansen, Kristian Larsen, Peter Steen Jensen, Gitte Moos Knudsen, Barbara Jacquelyn Sahakian, Dea Siggard Stenbæk, Patrick MacDonald Fisher
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Short-term intake of selective serotonin reuptake inhibitors (SSRIs) modulates threat-related amygdala responses in healthy individuals. However, how SSRI intake over a clinically relevant time period modulates threat-related amygdala respon
Externí odkaz:
https://doaj.org/article/df824400eaaf457cb27087aff1030fb1
Autor:
Tommaso Volpi, Lucia Maccioni, Maria Colpo, Giulia Debiasi, Amedeo Capotosti, Tommaso Ciceri, Richard E. Carson, Christine DeLorenzo, Andreas Hahn, Gitte Moos Knudsen, Adriaan A. Lammertsma, Julie C. Price, Vesna Sossi, Guobao Wang, Paolo Zanotti-Fregonara, Alessandra Bertoldo, Mattia Veronese
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Background The need for arterial blood data in quantitative PET research limits the wider usability of this imaging method in clinical research settings. Image-derived input function (IDIF) approaches have been proposed as a cost-effective a
Externí odkaz:
https://doaj.org/article/09297a4d1afa43e2bc6a7fe55f221ea4
Autor:
Silvia Elisabetta Portis Bruzzone, Arafat Nasser, Sagar Sanjay Aripaka, Marie Spies, Brice Ozenne, Peter Steen Jensen, Gitte Moos Knudsen, Vibe Gedsoe Frokjaer, Patrick MacDonald Fisher
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The serotonin transporter (5-HTT) critically shapes serotonin neurotransmission by regulating extracellular brain serotonin levels; it remains unclear to what extent 5-HTT levels in the human brain are genetically determined. Here we applied
Externí odkaz:
https://doaj.org/article/9c8f47aa77904a78966d873e14043b05
Autor:
Kristian Høj Reveles Jensen, Vibeke H. Dam, Melanie Ganz, Patrick MacDonald Fisher, Cheng-Teng Ip, Anjali Sankar, Maja Rou Marstrand-Joergensen, Brice Ozenne, Merete Osler, Brenda W. J. H. Penninx, Lars H. Pinborg, Vibe Gedsø Frokjaer, Gitte Moos Knudsen, Martin Balslev Jørgensen
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Major Depressive Disorder (MDD) is a heterogenous brain disorder, with potentially multiple psychosocial and biological disease mechanisms. This is also a plausible explanation for why patients do not respond equally well to treat
Externí odkaz:
https://doaj.org/article/5c5e9049498647299c8ad0ed52ae3969
Autor:
Vibeke Høyrup Dam, Dea Siggaard Stenbæk, Kristin Köhler-Forsberg, Cheng Ip, Brice Ozenne, Barbara Jacquelyn Sahakian, Gitte Moos Knudsen, Martin Balslev Jørgensen, Vibe Gedsoe Frokjaer
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Cognitive disturbances in major depressive disorder (MDD) constitute a critical treatment target and hold promise as an early predictor of antidepressant treatment response; yet their clinical relevance is not fully established. Therefore, w
Externí odkaz:
https://doaj.org/article/6b175c5514e4435589af750c3c07f3e9
Autor:
Nicole Fadahunsi, Jens Lund, Alberte Wollesen Breum, Cecilie Vad Mathiesen, Isabella Beck Larsen, Gitte Moos Knudsen, Anders Bue Klein, Christoffer Clemmensen
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Psilocybin and other serotonergic psychedelics have re-emerged as therapeutics for neuropsychiatric disorders, including addiction. Psilocybin induces long-lasting effects on behavior, likely due to its profound ability to alter consciousnes
Externí odkaz:
https://doaj.org/article/fab46ce76aa846c29991a6ba82691aa7
Autor:
Anders Jorgensen, Kristin Köhler-Forsberg, Trine Henriksen, Allan Weimann, Ivan Brandslund, Christina Ellervik, Henrik E. Poulsen, Gitte Moos Knudsen, Vibe G. Frokjaer, Martin B. Jorgensen
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Previous studies have indicated that antidepressants that inhibit the serotonin transporter reduces oxidative stress. DNA and RNA damage from oxidation is involved in aging and a range of age-related pathophysiological processes. Here, we st
Externí odkaz:
https://doaj.org/article/54b9a33f8eb442f8986956297ef339be
Autor:
Daniel Rødbro Burmester, Martin Korsbak Madsen, Attila Szabo, Sagar Sanjay Aripaka, Dea Siggaard Stenbæk, Vibe G. Frokjaer, Betina Elfving, Jens D. Mikkelsen, Gitte Moos Knudsen, Patrick MacDonald Fisher
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 13, Iss , Pp 100163- (2023)
Rationale: Psilocybin is a serotonergic psychedelic that has gained prominent attention recently as a potential therapeutic for neuropsychiatric disorders including Major Depressive Disorder. Pre-clinical and initial studies in humans suggest that se
Externí odkaz:
https://doaj.org/article/5a09e4aa76974378ba970fefc49b6caf
Autor:
Gjertrud Louise Laurell, Pontus Plavén-Sigray, Claus Svarer, R. Todd Ogden, Gitte Moos Knudsen, Martin Schain
Publikováno v:
NeuroImage, Vol 263, Iss , Pp 119620- (2022)
Molecular neuroimaging is today considered essential for evaluation of novel CNS drugs; it is used to quantify blood-brain barrier permeability, verify interaction with key target and determine the drug dose resulting in 50% occupancy, IC50. In spite
Externí odkaz:
https://doaj.org/article/fb55ae1d3f5f487b9b947c6edd72b463