Tir Is Essential for the Recruitment of Tks5 to Enteropathogenic Escherichia coli Pedestals.

Autor: Helene H Jensen, Hans N Pedersen, Eva Stenkjær, Gitte A Pedersen, Frédéric H Login, Lene N Nejsum

Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0141871 (2015)

Enteropathogenic Escherichia coli (EPEC) is a bacterial pathogen that infects the epithelial lining of the small intestine and causes diarrhea. Upon attachment to the intestinal epithelium, EPEC uses a Type III Secretion System to inject its own high

Externí odkaz: https://doaj.org/article/e91741d980a84a618422cbc009a71bc0

P-96 Stop for stress – a randomized controlled trial of an online intervention for work-related stress

Autor: Lea Nørgaard Sørensen, Gitte Laue Pedersen, Pernille Melander Thorsen, Jesper Pihl-Thingvad, Ane Marie Thulstrup, Morten Vejs Willert

Publikováno v: Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3532eda9346b00c39b16cc772262fbb6
https://doi.org/10.1136/oem-2023-epicoh.146

Characterizing Cutaneous Drug Delivery Using Open-Flow Microperfusion and Mass Spectrometry Imaging

Autor: Gitte Pommergaard Pedersen, Line Hollesen Schefe, Manfred Bodenlenz, Christian Janfelt, Frank Sinner, Stefan Eirefelt, André Huss Eriksson, Thomas Birngruber, Maja Lambert, Anne Mette Handler, Fredrik Johansson, Kim Troensegaard Nielsen, Nina Østergaard Knudsen

Publikováno v: Handler, A M, Eirefelt, S, Lambert, M, Johansson, F, Hollesen Schefe, L, Knudsen, N Ø, Bodenlenz, M, Birngruber, T, Sinner, F, Eriksson, A H, Pedersen, G P, Janfelt, C & Troensegaard Nielsen, K 2021, ' Characterizing Cutaneous Drug Delivery Using Open-Flow Microperfusion and Mass Spectrometry Imaging ', Molecular Pharmaceutics, vol. 18, no. 8, pp. 3063-3072 . https://doi.org/10.1021/acs.molpharmaceut.1c00285

Traditionally, cutaneous drug delivery is studied by skin accumulation or skin permeation, while alternative techniques may enable the interactions between the drug and the skin to be studied in more detail. Time-resolved skin profiling for pharmacok

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afaf40a0d690fd7ebd85237ac597828
https://curis.ku.dk/ws/files/336199777/MolecularPharmaceutics18_3063_3072_2021_preprint.pdf

Predicting in vivo performance of fenofibrate amorphous solid dispersions using in vitro non-sink dissolution and dissolution permeation setup

Autor: Gitte Pommergaard Pedersen, Karoline Aagaard Lentz, Carl Johan Sennbro, Anders Just Pedersen, Bente Steffansen, Jette Bredahl Jacobsen, Per-Ola Arvidsson, Jakob Plum, Diana Omkvist

Publikováno v: International Journal of Pharmaceutics. 610:121174

Amorphous solid dispersion (ASD) is emerging as a useful formulation strategy to increase the bioavailability of active pharmaceutical ingredients with poor solubility. In vitro dissolution testing under non-sink conditions has often been used to eva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa7f89bf78a1c8a57a4da21e0109a4d
https://doi.org/10.1016/j.ijpharm.2021.121174

MALDI mass spectrometry imaging as a complementary analytical method for improved skin distribution analysis of drug molecule and excipients

Autor: Christian Janfelt, Mariam Fallah, Gitte Pommergaard Pedersen, Anne Mette Handler, Kim Troensegaard Nielsen, Anders Just Pedersen

Publikováno v: International Journal of Pharmaceutics. 590:119949

In cutaneous drug delivery, it is widely accepted that the choice of excipients affects the delivery of a drug molecule to the skin. MALDI mass spectrometry imaging (MALDI-MSI) is an imaging technique which enables the simultaneous detection of multi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8a8ad4c0c5661c95da02a7ce69fda8
https://doi.org/10.1016/j.ijpharm.2020.119949