Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Gitanjali Jayachandran"'
Autor:
Lucia Ruojia Wu, Peng Dai, Michael Xiangjiang Wang, Sherry Xi Chen, Evan N. Cohen, Gitanjali Jayachandran, Jinny Xuemeng Zhang, Angela V. Serrano, Nina Guanyi Xie, Naoto T. Ueno, James M. Reuben, Carlos H. Barcenas, David Yu Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Highly multiplexed ddPCR for sensitive nucleic acid quantitation remains challenging due to limited fluorescence channels. Here the authors report quantitative amplicon sequencing (QASeq), a PCR-based molecular barcoding NGS approach which is compati
Externí odkaz:
https://doaj.org/article/4d7f4e4784404a73a971f604e13766e8
Autor:
Evan N. Cohen, Gitanjali Jayachandran, Hui Gao, Phillip Peabody, Heather B. McBride, Franklin D. Alvarez, Megumi Kai, Juhee Song, Yu Shen, Jie S. Willey, Bora Lim, Vicente Valero, Naoto T. Ueno, James M. Reuben
Publikováno v:
Cancers, Vol 15, Iss 5, p 1616 (2023)
Circulating tumor cells (CTCs) are indicators of metastatic spread and progression. In a longitudinal, single-center trial of patients with metastatic breast cancer starting a new line of treatment, a microcavity array was used to enrich CTCs from 18
Externí odkaz:
https://doaj.org/article/22cbe30a996040929685f879f2eadd3f
Autor:
Evan N. Cohen, Gitanjali Jayachandran, Richard G. Moore, Massimo Cristofanilli, Julie E. Lang, Joseph D. Khoury, Michael F. Press, Kyu Kwang Kim, Negar Khazan, Qiang Zhang, Youbin Zhang, Pushpinder Kaur, Roberta Guzman, Michael C. Miller, James M. Reuben, Naoto T. Ueno
Publikováno v:
Cancers, Vol 14, Iss 21, p 5238 (2022)
Circulating tumor cells (CTCs) captured from the blood of cancer patients may serve as a surrogate source of tumor material that can be obtained via a venipuncture (also known as a liquid biopsy) and used to better understand tumor characteristics. H
Externí odkaz:
https://doaj.org/article/2a9a1f523e2547b0a01ac0f0a024312a
Autor:
Evan N Cohen, Gitanjali Jayachandran, Max R Hardy, Ananya M Venkata Subramanian, Xiangtian Meng, James M Reuben
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241123 (2020)
Circulating tumor cells (CTC) isolated from the peripheral blood of cancer patients by a minimally invasive procedure provide surrogate markers of the tumor that can be repeatedly sampled. However, the selection and enumeration of CTCs by traditional
Externí odkaz:
https://doaj.org/article/c311e38fa30d4b6cb4ae08c68e9a4326
Autor:
Bingbing Dai, Shaoyu Yan, Humberto Lara-Guerra, Hiroyuki Kawashima, Ryo Sakai, Gitanjali Jayachandran, Mourad Majidi, Reza Mehran, Jing Wang, B Nebiyou Bekele, Veerabhadran Baladandayuthapani, Suk-Young Yoo, Ying Wang, Jun Ying, Feng Meng, Lin Ji, Jack A Roth
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0123967 (2015)
Expression of the tumor suppressor gene TUSC2 is reduced or absent in most lung cancers and is associated with worse overall survival. In this study, we restored TUSC2 gene expression in several wild type EGFR non-small cell lung cancer (NSCLC) cell
Externí odkaz:
https://doaj.org/article/4b0fbfba8b0c41f0b85418d2f59eecb8
Autor:
Charles Lu, David J Stewart, J Jack Lee, Lin Ji, Rajagopal Ramesh, Gitanjali Jayachandran, Maria I Nunez, Ignacio I Wistuba, Jeremy J Erasmus, Marshall E Hicks, Elizabeth A Grimm, James M Reuben, Veerabhadran Baladandayuthapani, Nancy S Templeton, John D McMannis, Jack A Roth
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34833 (2012)
Tumor suppressor gene TUSC2/FUS1 (TUSC2) is frequently inactivated early in lung cancer development. TUSC2 mediates apoptosis in cancer cells but not normal cells by upregulation of the intrinsic apoptotic pathway. No drug strategies currently exist
Externí odkaz:
https://doaj.org/article/eb78a39f4a0d4587ba18e50d4d831184
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e11994 (2010)
NPRL2, one of the tumor suppressor genes residing in a 120-kb homozygous deletion region of human chromosome band 3p21.3, has a high degree of amino acid sequence homology with the nitrogen permease regulator 2 (NPR2) yeast gene, and mutations of NPR
Externí odkaz:
https://doaj.org/article/3c276291838a495d80835f1e0e9b173e
Autor:
Gitanjali Jayachandran, Ann M. Fallon
Publikováno v:
Journal of Insect Science, Vol 2, p 21 (2002)
Homologous transfection systems provide a useful tool for characterizing promoters and other regulatory elements from cloned genes. We have used cultured Aedes albopictus C7-10 mosquito cells to evaluate expression of 20-hydroxyecdysone-inducible gen
Externí odkaz:
https://doaj.org/article/5a950b31d78a44638e021b4198f7fc41
Autor:
Evan N. Cohen, Gitanjali Jayachandran, Hui Gao, Phillip Peabody, Heather B. McBride, Franklin D. Alvarez, Pablo Lopez Bravo, Wei Qiao, Suyu Liu, Luyang Yao, Steven H. Lin, James M. Reuben
Publikováno v:
Translational Lung Cancer Research. 12:109-126
Autor:
Jangsoon Lee, Kumiko Kida, Huey Liu, Ganiraju C. Manyam, Young Jin Gi, Asha S. Multani, Jing Wang, Gitanjali Jayachandran, James M. Reuben, Lei Huo, Debu Tripathy, Naoto T. Ueno
Background: Anti-HER2 therapies, including the HER2 antibody-drug conjugates trastuzumab emtansine (T-DM1) and trastuzumab deruxtecan (T-DXd), have improved survival outcomes for patients with HER2-overexpressing/amplified (HER2+) metastatic breast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a59822d2f7a5b56c38a4245e7783420
https://doi.org/10.21203/rs.3.rs-2918702/v1
https://doi.org/10.21203/rs.3.rs-2918702/v1