Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Git, Chung"'
Autor:
Valeria Chichagova, Maria Georgiou, Madeleine Carter, Birthe Dorgau, Gerrit Hilgen, Joseph Collin, Rachel Queen, Git Chung, Jila Ajeian, Marina Moya‐Molina, Stefan Kustermann, Francois Pognan, Philip Hewitt, Michael Schmitt, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako
Publikováno v:
Journal of Cellular and Molecular Medicine. 27:435-445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e355d2946cbd046ef929311d3cdfb0b9
https://doi.org/10.1111/jcmm.17670
https://doi.org/10.1111/jcmm.17670
Autor:
Hany S. Zinad, Chanachai Sae-Lee, Maria Ascensión Ariza-Mateos, Grace Adamson, Mushtaq Mufleh Khazeem, Amber Knox, Git Chung, Jelena Mann, Andreas Werner
Publikováno v:
Non-Coding RNA, Vol 8, Iss 1, p 19 (2022)
Natural antisense transcripts (NATs) constitute a significant group of regulatory, long noncoding RNAs. They are prominently expressed in testis but are also detectable in other organs. NATs are transcribed at low levels and co-expressed with related
Externí odkaz:
https://doaj.org/article/d129e5254a51461a886c3973161d9f2d
Autor:
Adriana Buskin, Lili Zhu, Valeria Chichagova, Basudha Basu, Sina Mozaffari-Jovin, David Dolan, Alastair Droop, Joseph Collin, Revital Bronstein, Sudeep Mehrotra, Michael Farkas, Gerrit Hilgen, Kathryn White, Kuan-Ting Pan, Achim Treumann, Dean Hallam, Katarzyna Bialas, Git Chung, Carla Mellough, Yuchun Ding, Natalio Krasnogor, Stefan Przyborski, Simon Zwolinski, Jumana Al-Aama, Sameer Alharthi, Yaobo Xu, Gabrielle Wheway, Katarzyna Szymanska, Martin McKibbin, Chris F. Inglehearn, David J. Elliott, Susan Lindsay, Robin R. Ali, David H. Steel, Lyle Armstrong, Evelyne Sernagor, Henning Urlaub, Eric Pierce, Reinhard Lührmann, Sushma-Nagaraja Grellscheid, Colin A. Johnson, Majlinda Lako
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Mutations in pre-mRNA processing factors cause autosomal dominant retinitis pigmentosa. Here the authors provide insights into the pathophysiological mechanisms underlying non-syndromic retinal disease caused by heterozygous mutations in genes encodi
Externí odkaz:
https://doaj.org/article/39722a7de98941cab07e48fc0b8400de
Autor:
Alex Gledhill, Rachael Bowen, Michael Bartels, Andrew Bond, Git Chung, Colin Brown, Keith Pye, Tarang Vora
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 52(5)
Metabolism data for MCPA in rat, dog and human shows a single oral dose is quantitatively and rapidly absorbed with evidence of non-linear kinetics at100 mg/kg bw. The extent of metabolism is low and consistent between rat and human, with substantial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94548390b40b33a4da260b0d567401c
https://pubmed.ncbi.nlm.nih.gov/35822285
https://pubmed.ncbi.nlm.nih.gov/35822285
Autor:
Hany S, Zinad, Chanachai, Sae-Lee, Maria Ascensión, Ariza-Mateos, Grace, Adamson, Mushtaq Mufleh, Khazeem, Amber, Knox, Git, Chung, Jelena, Mann, Andreas, Werner
Publikováno v:
Non-coding RNA. 8(1)
Natural antisense transcripts (NATs) constitute a significant group of regulatory, long noncoding RNAs. They are prominently expressed in testis but are also detectable in other organs. NATs are transcribed at low levels and co-expressed with related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc59155e8ca9014d2b854534067334d6
https://pubmed.ncbi.nlm.nih.gov/35202092
https://pubmed.ncbi.nlm.nih.gov/35202092
Autor:
Git Chung, Edward I Patterson, Maria Georgiou, Grant L. Hughes, Majlinda Lako, Shaun H. Pennington, Ivo Djidrovski, Lyle Armstrong, Martine J. Smit, Jelle van den Bor, Aitor Casas-Sanchez, Giancarlo A. Biagini, Marina Moya-Molina
Publikováno v:
STEM CELLS
Stem Cells, 39(10), 1310-1321. AlphaMed Press
Stem Cells (Dayton, Ohio)
Djidrovski, I, Georgiou, M, Hughes, G L, Patterson, E I, Casas-Sanchez, A, Pennington, S H, Biagini, G A, Moya-Molina, M, van den Bor, J, Smit, M J, Chung, G, Lako, M & Armstrong, L 2021, ' SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells ', Stem Cells, vol. 39, no. 10, pp. 1310-1321 . https://doi.org/10.1002/stem.3422
Stem Cells, 39(10), 1310-1321. AlphaMed Press
Stem Cells (Dayton, Ohio)
Djidrovski, I, Georgiou, M, Hughes, G L, Patterson, E I, Casas-Sanchez, A, Pennington, S H, Biagini, G A, Moya-Molina, M, van den Bor, J, Smit, M J, Chung, G, Lako, M & Armstrong, L 2021, ' SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells ', Stem Cells, vol. 39, no. 10, pp. 1310-1321 . https://doi.org/10.1002/stem.3422
As one of the primary points of entry of xenobiotic substances and infectious agents into the body, the lungs are subject to a range of dysfunctions and diseases that together account for a significant number of patient deaths. In view of this, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6561c13f65bbf01facea5c691ff657
Autor:
Tomoya Yukawa, Akio Imanishi, Piyush Bajaj, Matthew Wagoner, Colin D. Brown, Yuichi Takai, Keith Pye, Git Chung
Publikováno v:
Toxicology. 442
Drug induced kidney injury (DIKI) is a common reason for compound attrition in drug development pipelines with proximal tubule epithelial cells (PTECs) most commonly associated with DIKI. Here, we investigated freshly isolated human (hPTECs) as an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad590fbf5d11c46ab0567a75c2e13412
https://pubmed.ncbi.nlm.nih.gov/32622972
https://pubmed.ncbi.nlm.nih.gov/32622972
Autor:
Colin D. Brown, Git Chung, Melissa Chan, Michael J. Bartels, Marco Corvaro, Claire Terry, Sean C. Gehen
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 116
A review of pharmacokinetic and metabolism studies show that triclopyr is well absorbed from the oral route in numerous species (≥80%), primarily as parent compound. Absorption is quite rapid in rats, dogs and human volunteers. Plasma or blood clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3128a92b3c8d8723461c98f1d326db10
https://pubmed.ncbi.nlm.nih.gov/32640299
https://pubmed.ncbi.nlm.nih.gov/32640299
Autor:
Johannes L Zakrzewski, Ben S. Barksby, Jeremy French, Luc Schoonjans, Amy L Collins, Jelena Mann, Matthias Trost, Stuart Robinson, Ulf Klein, Morten A. Karsdal, Hannah L Paish, Amber Knox, Peter Carmeliet, Lee A. Borthwick, Andrew D Blanchard, Git Chung, Rainie Cameron, Neil S. Sheerin, Laure-Anne Teuwen, Ingmar Mederacke, Lucy M Gee, Colin D.A. Brown, Carmel B. Nanthakumar, Thomas G. Bird, Jack Leslie, Sandra Murphy, Robert F. Schwabe, Fiona Oakley, Marina García Macia, Xin Xu, Andrew J. Fisher, Derek A. Mann, Derek Manas, Rachel A. Burgoyne, William J Reilly, Steven A. White, Charlotte Bragg, Saimir Luli, Gourab Sen, Marco Y W Zaki, Colin Nixon, Julie C. Worrell
Publikováno v:
Nature Metabolism
Leslie, J, Macia, M G, Luli, S, Worrell, J C, Reilly, W J, Paish, H L, Knox, A, Barksby, B S, Gee, L M, Zaki, M Y W, Collins, A L, Burgoyne, R A, Cameron, R, Bragg, C, Xu, X, Chung, G W, Brown, C D A, Blanchard, A D, Nanthakumar, C B, Karsdal, M, Robinson, S M, Manas, D M, Sen, G, French, J, White, S A, Murphy, S, Trost, M, Zakrzewski, J L, Klein, U, Schwabe, R F, Mederacke, I, Nixon, C, Bird, T, Teuwen, L-A, Schoonjans, L, Carmeliet, P, Mann, J, Fisher, A J, Sheerin, N S, Borthwick, L A, Mann, D A & Oakley, F 2020, ' c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis ', Nature Metabolism, vol. 2, no. 11, pp. 1350-1367 . https://doi.org/10.1038/s42255-020-00306-2
Nat Metab
Digital.CSIC. Repositorio Institucional del CSIC
instname
Leslie, J, Macia, M G, Luli, S, Worrell, J C, Reilly, W J, Paish, H L, Knox, A, Barksby, B S, Gee, L M, Zaki, M Y W, Collins, A L, Burgoyne, R A, Cameron, R, Bragg, C, Xu, X, Chung, G W, Brown, C D A, Blanchard, A D, Nanthakumar, C B, Karsdal, M, Robinson, S M, Manas, D M, Sen, G, French, J, White, S A, Murphy, S, Trost, M, Zakrzewski, J L, Klein, U, Schwabe, R F, Mederacke, I, Nixon, C, Bird, T, Teuwen, L-A, Schoonjans, L, Carmeliet, P, Mann, J, Fisher, A J, Sheerin, N S, Borthwick, L A, Mann, D A & Oakley, F 2020, ' c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis ', Nature Metabolism, vol. 2, no. 11, pp. 1350-1367 . https://doi.org/10.1038/s42255-020-00306-2
Nat Metab
Digital.CSIC. Repositorio Institucional del CSIC
instname
Fibrosis is a common pathological feature of chronic disease. Deletion of the NF-κB subunit c-Rel limits fibrosis in multiple organs, although the mechanistic nature of this protection is unresolved. Using cell-specific gene-targeting manipulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29e2b56012d84a4113925afd0985a4b
Autor:
Git Chung, Colin D.A. Brown, Joe Bentz, Akshata Yalvigi, Caroline Lee, Michael O'Connor, Adam Lynn, Harma Ellens, Aqsaa Chaudhry
Publikováno v:
Drug Metabolism and Disposition. 46:279-290
It has been previously demonstrated that IC50 values for inhibition of digoxin transport across confluent polarized cell monolayers are system-dependent. Digoxin IC50 data from five laboratories participating in the P-glycoprotein (P-gp) IC50 Initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30ade2ecaf40d6d7a551308a028b43ea
https://doi.org/10.1124/dmd.117.075606
https://doi.org/10.1124/dmd.117.075606