Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Gissou Azabdaftari"'
Autor:
Manojit M. Swamynathan, Grinu Mathew, Andrei Aziz, Chris Gordon, Andrew Hillowe, Hehe Wang, Aashna Jhaveri, Jude Kendall, Hilary Cox, Michael Giarrizzo, Gissou Azabdaftari, Robert C. Rizzo, Sarah D. Diermeier, Iwao Ojima, Agnieszka B. Bialkowska, Martin Kaczocha, Lloyd C. Trotman
Publikováno v:
Cancers, Vol 16, Iss 1, p 60 (2023)
Resistance to standard of care taxane and androgen deprivation therapy (ADT) causes the vast majority of prostate cancer (PC) deaths worldwide. We have developed RapidCaP, an autochthonous genetically engineered mouse model of PC. It is driven by the
Externí odkaz:
https://doaj.org/article/1d109320975d418cab3e6b18f038b834
Autor:
Hayley C. Affronti, Aryn M. Rowsam, Anthony J. Pellerite, Spencer R. Rosario, Mark D. Long, Justine J. Jacobi, Anna Bianchi-Smiraglia, Christoph S. Boerlin, Bryan M. Gillard, Ellen Karasik, Barbara A. Foster, Michael Moser, John H. Wilton, Kristopher Attwood, Mikhail A. Nikiforov, Gissou Azabdaftari, Roberto Pili, James G. Phillips, Robert A. Casero, Dominic J. Smiraglia
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Prostate cancer cells depend on MTAP, the rate-limiting enzyme involved in the methionine salvage pathway, to cope with increased polyamine biosynthesis. Here, the authors show that inducing upregulation of polyamine biosynthesis and targeting MTAP s
Externí odkaz:
https://doaj.org/article/e67ec780a1554759a4b84c3b9ee77ce5
Autor:
Dharmesh Gopalakrishnan, Rohit K. Jain, Laurie Herbst, Marcus Sikorski, Silpa Mandava, Gissou Azabdaftari, Bo Xu, Charles LeVea, Kevin Robillard, Marc S. Ernstoff, Saby George
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy. Nivolumab, an anti-PD-1 monoclonal antibody, markedly improved overall survival in advanced renal cell carcinoma (RCC). However, ICIs can rarely trigger massive inflammation, a p
Externí odkaz:
https://doaj.org/article/50d83b3c0363479b9e2e6506bed0f3ec
Autor:
Jason B. Muhitch, Nicholas C. Hoffend, Gissou Azabdaftari, Austin Miller, Wiam Bshara, Carl D. Morrison, Thomas Schwaab, Scott I. Abrams
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Tumor-associated macrophages have been well-characterized in solid malignancies, including renal cell carcinoma and generally correlate with poor prognosis. However, the molecular mechanisms which govern intratumoral macrophage behavior and
Externí odkaz:
https://doaj.org/article/e4701ddebf774665811e8d7e4d12c060
Autor:
Terrence M. Vance, Gissou Azabdaftari, Elena A. Pop, Sang Gil Lee, L. Joseph Su, Elizabeth T. H. Fontham, Jeannette T. Bensen, Susan E. Steck, Lenore Arab, James L. Mohler, Ming-Hui Chen, Sung I. Koo, Ock K. Chun
Publikováno v:
Prostate Cancer, Vol 2015 (2015)
Background. Prostate cancer is the most common noncutaneous cancer and second leading cause of cancer-related mortality in men in the US. Growing evidence suggests that oxidative stress is involved in prostate cancer. Methods. In this study, thioredo
Externí odkaz:
https://doaj.org/article/364d09306d2c4b9f9f538814ba60b74b
Autor:
Barbara A Foster, Kalyan J Gangavarapu, Grinu Mathew, Gissou Azabdaftari, Carl D Morrison, Austin Miller, Wendy J Huss
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55062 (2013)
Stem cell enrichment provides a tool to examine prostate stem cells obtained from benign and malignant tissue. Functional assays can enrich stem cells based on common stem cell phenotypes, such as high ATP binding cassette (ABC) transporter mediated
Externí odkaz:
https://doaj.org/article/d9ad1989e8394cc58975639cbff15b3d
Publikováno v:
Diagnostic Cytopathology.
Autor:
Levi A. Garraway, Isaac J. Powell, Mark A. Rubin, Pablo Tamayo, Jill Mesirov, Eliezer M. Van Allen, Stacey Gabriel, Francesca Demichelis, Angelo M. De Marzo, Karen Sfanos, Anna Woloszynska-Read, Gissou Azabdaftari, Jong Wook Kim, Joseph R. Osborne, Alessandro Romanel, Matan Hofree, Jeremy Chimene-Weiss, Eejung Kim, Beerinder Karir, Francesca Khani, Saud Aldubayan, Brian D. Robinson, Stephanie A. Mullane, Samira Bahl, Bokang Rabasha, Ali Amin-Mansour, Maria Baco, Coyin Oh, Andrea Garofalo, Juan Miguel Mosquera, Franklin W. Huang
Supplemental Table 1. Overall cohort characteristics of AAPC whole exome sequencing cohort (n=102) Supplemental Table 2. Clinical and pathological characteristics of AAPC WES discovery cohort (n=102) Supplemental Table 3. Comparison of numbers of tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7d2d64b183edb401be6c8eb683afbd
https://doi.org/10.1158/2159-8290.22531900
https://doi.org/10.1158/2159-8290.22531900
Autor:
Levi A. Garraway, Isaac J. Powell, Mark A. Rubin, Pablo Tamayo, Jill Mesirov, Eliezer M. Van Allen, Stacey Gabriel, Francesca Demichelis, Angelo M. De Marzo, Karen Sfanos, Anna Woloszynska-Read, Gissou Azabdaftari, Jong Wook Kim, Joseph R. Osborne, Alessandro Romanel, Matan Hofree, Jeremy Chimene-Weiss, Eejung Kim, Beerinder Karir, Francesca Khani, Saud Aldubayan, Brian D. Robinson, Stephanie A. Mullane, Samira Bahl, Bokang Rabasha, Ali Amin-Mansour, Maria Baco, Coyin Oh, Andrea Garofalo, Juan Miguel Mosquera, Franklin W. Huang
Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e6a44282c5e8986299f440da59e71c
https://doi.org/10.1158/2159-8290.22531903
https://doi.org/10.1158/2159-8290.22531903
Autor:
Levi A. Garraway, Isaac J. Powell, Mark A. Rubin, Pablo Tamayo, Jill Mesirov, Eliezer M. Van Allen, Stacey Gabriel, Francesca Demichelis, Angelo M. De Marzo, Karen Sfanos, Anna Woloszynska-Read, Gissou Azabdaftari, Jong Wook Kim, Joseph R. Osborne, Alessandro Romanel, Matan Hofree, Jeremy Chimene-Weiss, Eejung Kim, Beerinder Karir, Francesca Khani, Saud Aldubayan, Brian D. Robinson, Stephanie A. Mullane, Samira Bahl, Bokang Rabasha, Ali Amin-Mansour, Maria Baco, Coyin Oh, Andrea Garofalo, Juan Miguel Mosquera, Franklin W. Huang
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e234b8b353d921fe1e1e2d445fb53b2
https://doi.org/10.1158/2159-8290.22531909
https://doi.org/10.1158/2159-8290.22531909