Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Gisselle N. Medina"'
Autor:
Stanley Bram, Graeme Lindsey, Jenny Drnevich, Fangxiu Xu, Marcin Wozniak, Gisselle N. Medina, Angad P. Mehta
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Pork is the most widely consumed meat on the planet, placing swine health as a critical factor for both the world economy and the food industry. Infectious diseases in pigs not only threaten these sectors but also raise zoonotic concerns, as
Externí odkaz:
https://doaj.org/article/20b2da09a5a44eb687cfaf05343ded2c
Autor:
Rohana P. Dassanayake, Harish Menghwar, Kathryn A. Bickel, David J. Holthausen, Hao Ma, Fayna Diaz-San Segunda, Monica Rodriguez-Calzada, Gisselle N. Medina, Sarah Attreed, Shollie M. Falkenberg, Carly Kanipe, Randy E. Sacco, Teresa De Los Santos, Eduardo Casas
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe antiviral activity of recombinant bovine interferon lambda 3 (bovIFN-λ3) against bovine viral diarrhea virus (BVDV) has been demonstrated in vitro in Madin-Darby bovine kidney cells (MDBK) and in vivo in cattle. However, anti-BVDV ac
Externí odkaz:
https://doaj.org/article/325136bf3352431cb58b26953ab8a24b
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1071 (2024)
Foot-and-mouth disease (FMD) is globally recognized as a highly economically devastating and prioritized viral disease affecting livestock. Vaccination remains a crucial preventive measure against FMD. The improvement of current vaccine platforms cou
Externí odkaz:
https://doaj.org/article/96510a976dc84f48b7ac0c5f36270ef8
Autor:
Sarah E. Attreed, Christina Silva, Monica Rodriguez-Calzada, Aishwarya Mogulothu, Sophia Abbott, Paul Azzinaro, Peter Canning, Lillian Skidmore, Jay Nelson, Nick Knudsen, Gisselle N. Medina, Teresa de los Santos, Fayna Díaz-San Segundo
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Foot-and-mouth disease (FMD) is a vesicular disease of cloven-hoofed animals with devastating economic implications. The current FMD vaccine, routinely used in enzootic countries, requires at least 7 days to induce protection. However, FMD vaccinatio
Externí odkaz:
https://doaj.org/article/3ee70f9a70464224baed98e2e52dc037
Autor:
Paul A. Azzinaro, Gisselle N. Medina, Devendra Rai, Elizabeth Ramirez-Medina, Edward Spinard, Monica Rodriguez-Calzada, James Zhu, Elizabeth Rieder, Teresa de los Santos, Fayna Díaz-San Segundo
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
The foot-and-mouth disease virus (FMDV) leader proteinase (Lpro) is a papain like protease that cleaves the viral polyprotein and several host factors affecting host cell translation and induction of innate immunity. Introduction of Lpro mutations ab
Externí odkaz:
https://doaj.org/article/2e733e01cba842d290abcaa40b87ced2
Autor:
Lauro Velazquez-Salinas, Gisselle N. Medina, Federico Valdez, Selene Zarate, Shannon Collinson, James J. Zhu, Luis L. Rodriguez
Publikováno v:
Pathogens, Vol 12, Iss 7, p 896 (2023)
Vesicular stomatitis virus (VSV) is an emergent virus affecting livestock in the US. Previously, using a recombinant VSV carrying the M51R mutation in the matrix protein (rNJ0612NME6-M51R), we evaluated the pathogenesis of this virus in pigs. Our res
Externí odkaz:
https://doaj.org/article/e97b3250dc854d8a8f7777d7c2005535
Autor:
Gisselle N. Medina, Edward Spinard, Paul A. Azzinaro, Monica Rodriguez-Calzada, Joseph Gutkoska, Anna Kloc, Elizabeth A. Rieder, Bruce E. Taillon, Stephen Mueller, Teresa de los Santos, Fayna Diaz-San Segundo
Publikováno v:
Viruses, Vol 15, Iss 6, p 1332 (2023)
Foot-and-mouth disease (FMD), caused by the FMD virus (FMDV), is a highly contagious disease of cloven-hoofed livestock that can have severe economic impacts. Control and prevention strategies, including the development of improved vaccines, are urge
Externí odkaz:
https://doaj.org/article/d1b9122ebe054f7f92f32ace88ff628e
Autor:
Edward Spinard, Ian Fish, Paul A. Azzinaro, Monica Rodriguez-Calzada, Ethan J. Hartwig, George R. Smoliga, Aishwarya Mogulothu, Jonathan Arzt, Teresa de los Santos, Gisselle N. Medina
Publikováno v:
Viruses, Vol 15, Iss 3, p 670 (2023)
Codon deoptimization (CD) has been recently used as a possible strategy to derive foot-and-mouth disease (FMD) live-attenuated vaccine (LAV) candidates containing DIVA markers. However, reversion to virulence, or loss of DIVA, from possible recombina
Externí odkaz:
https://doaj.org/article/d469aac7fd614607908afc0de085fa4c
Autor:
Ian Fish, Carolina Stenfeldt, Edward Spinard, Gisselle N. Medina, Paul A. Azzinaro, Miranda R. Bertram, Lauren Holinka, George R. Smoliga, Ethan J. Hartwig, Teresa de los Santos, Jonathan Arzt
Publikováno v:
Pathogens, Vol 11, Iss 6, p 644 (2022)
Viral recombination contributes to the emergence of novel strains with the potential for altered host range, transmissibility, virulence, and immune evasion. For foot-and-mouth disease virus (FMDV), cell culture experiments and phylogenetic analyses
Externí odkaz:
https://doaj.org/article/9d6717109caa4e0eac787cf976ef1171
Autor:
Fayna Diaz-San Segundo, Gisselle N. Medina, Paul Azzinaro, Joseph Gutkoska, Aishwarya Mogulothu, Sarah E. Attreed, Kimberly R. Lombardi, Jacob Shields, Teresa A. Hudock, Teresa de los Santos
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Interferons (IFNs) are considered the first line of defense against viral diseases. Due to their ability to modulate immune responses, they have become an attractive therapeutic option to control virus infections. In fact, like many other viruses, fo
Externí odkaz:
https://doaj.org/article/8cf0e49df36c4455b9ff7da55c9d983c