Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Gisli G. Einarsson"'
Autor:
Gisli G. Einarsson, Bart M. Vanaudenaerde, Christopher D. Spence, Andrew J. Lee, Mieke Boon, Geert M. Verleden, J. Stuart Elborn, Lieven J. Dupont, Dirk Van Raemdonck, Deirdre F. Gilpin, Robin Vos, Stijn E. Verleden, Michael M. Tunney
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
To date, investigations of the microbiota in the lungs of people with Cystic Fibrosis (PWCF) have primarily focused on microbial community composition in luminal mucus, with fewer studies observing the microbiota in tissue samples from explanted lung
Externí odkaz:
https://doaj.org/article/e3be9f4b85574b029f366d976f295448
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The advent of high-throughput multi-omics technologies has underpinned the expansion in lung microbiome research, increasing our understanding of the nature, complexity and significance of the polymicrobial communities harbored by people with CF (PWC
Externí odkaz:
https://doaj.org/article/cffcc90dd08e4dbc978fbd6fc1d6820e
Autor:
Gisli G. Einarsson, Jiangchao Zhao, John J. LiPuma, Damian G. Downey, Michael M. Tunney, J. Stuart Elborn
Publikováno v:
ERJ Open Research, Vol 5, Iss 3 (2019)
Ecological relationships between bacteria are important when considering variation in bacterial communities in humans, with such variation playing an important role in both health and disease. Using high-throughput sequence data of the 16S rRNA marke
Externí odkaz:
https://doaj.org/article/52ae508bf7274590a489751702492841
Autor:
Dermot A. Linden, Hong Guo-Parke, Michael C. McKelvey, Gisli G. Einarsson, Andrew J. Lee, Derek J. Fairley, Vanessa Brown, Gavin Lundy, Christina Campbell, Danielle Logan, Margaret McFarland, Dave Singh, Daniel F. McAuley, Clifford C. Taggart, Joseph C. Kidney
Publikováno v:
Chest.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f624298e6d8b08c044da60b71ed2641f
https://doi.org/10.1016/j.chest.2023.03.040
https://doi.org/10.1016/j.chest.2023.03.040
Autor:
Deirdre Gilpin, Barry J. Plant, Fergus Shanahan, J. Stuart Elborn, David Mullane, Joseph A. Eustace, Gisli G. Einarsson, N.J. Ronan, D. Mooney, M. Mccarthy, Desmond M. Murphy, Muireann NiChroinin, Michael M. Tunney, C. McGettigan, Yvonne McCarthy
Publikováno v:
Einarsson, G G, Ronan, N J, Mooney, D, McGettigan, C, Mullane, D, NiChroinin, M, Shanahan, F, Murphy, D M, McCarthy, M, McCarthy, Y, Eustace, J A, Gilpin, D F, Elborn, J S, Plant, B J & Tunney, M M 2021, ' Extended-culture and culture-independent molecular analysis of the airway microbiota in cystic fibrosis following CFTR modulation with ivacaftor ', Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society . https://doi.org/10.1016/j.jcf.2020.12.023
BACKGROUND: Treatment with Ivacaftor provides a significant clinical benefit in people with cystic fibrosis (PWCF) with the class III G551D-CFTR mutation. This study determined the effect of CFTR modulation with ivacaftor on the lung microbiota in PW
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877ad0b01f143a4d9a8c943c92ad22db
https://doi.org/10.1016/j.jcf.2020.12.023
https://doi.org/10.1016/j.jcf.2020.12.023
Publikováno v:
Allen, D M, Einarsson, G G, Tunney, M M & Bell, S E J 2022, ' Characterization of Bacteria Using Surface-Enhanced Raman Spectroscopy (SERS): Influence of Microbiological Factors on the SERS Spectra ', Analytical chemistry, vol. 94, no. 26, pp. 9327–9335 . https://doi.org/10.1021/acs.analchem.2c00817
SERS is currently being explored as a rapid method for identification of bacteria but variation in the experimental procedures has resulted in considerable variation in the spectra reported for a range of bacterial species. Here, we show that mixing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634e93f5c9dbff1cf14f8a842ba64e4f
https://pure.qub.ac.uk/en/publications/2a78c398-8a4b-49aa-8728-7b58ac0f3079
https://pure.qub.ac.uk/en/publications/2a78c398-8a4b-49aa-8728-7b58ac0f3079
Autor:
Anthony De Soyza, Michael M. Tunney, Deirdre Gilpin, Kathryn Ferguson, Zina Alfahl, Mary P. Carroll, J. Stuart Elborn, Jeremy Brown, Gisli G. Einarsson, Michael R. Loebinger, Chris Johnson, Judy Bradley, Katherine O'Neill, Adam T. Hill, Timothy Gatheral, John R. Hurst, James D. Chalmers
Publikováno v:
Respiratory infections and bronchiectasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e2a3a1e89379accd79f4f5d55b61b9
https://doi.org/10.1183/13993003.congress-2021.oa1309
https://doi.org/10.1183/13993003.congress-2021.oa1309
Autor:
Stefano Aliberti, Guillermo Suarez-Cuartin, Amelia Shoemark, Megan Crichton, Jennifer Pollock, Ashley Giam, Gisli G. Einarsson, Elizabeth Furrie, Christopher J. Fong, James D. Chalmers, Thomas C. Fardon, Jeffrey T.-J. Huang, Joseph Elborn, Andrew Cassidy, Alison Dicker, Simon Finch, Holly R. Keir, Oriol Sibila
Publikováno v:
BTS/BALR/BLF Early Career Investigator Awards.
Introduction Neutrophil extracellular traps (NETs) are a form of antimicrobial defence which have been implicated in multiple inflammatory diseases. This study investigated the role of NETs in bronchiectasis, a neutrophilic disease which lacks therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb6ff294f31427574ee110fde5a88dab
https://doi.org/10.1136/thorax-2020-btsabstracts.6
https://doi.org/10.1136/thorax-2020-btsabstracts.6
Autor:
Yan Hui Giam, Megan Crichton, Stefano Aliberti, Christopher J. Fong, Jennifer Pollock, James D. Chalmers, Holly R. Keir, Erin Cant, Francesco Blasi, Mike Lonergan, Jodie L. Simpson, Martina Oriano, Oriol Sibila, Geraint B. Rogers, J. Stuart Elborn, Elizabeth Furrie, Lidia Perea, Alison Dicker, Guillermo Suarez-Cuartin, Gisli G. Einarsson, Amelia Shoemark, Jeffrey T.-J. Huang, Simon Finch
Publikováno v:
The Lancet. Respiratory medicine. 9(8)
Summary Background Bronchiectasis is predominantly a neutrophilic inflammatory disease. There are no established therapies that directly target neutrophilic inflammation because little is understood of the underlying mechanisms leading to severe dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d9767d5a6a55a27331aea28cf0636a
https://pubmed.ncbi.nlm.nih.gov/33609487
https://pubmed.ncbi.nlm.nih.gov/33609487
Autor:
Michael M. Tunney, Gisli G. Einarsson, A.J. Lee, Stephen Rowan, T. Lynch, Judy Bradley, Katherine O'Neill, John Lawson, L. McIlreavey, Alex Horsley, J. Stuart Elborn
Publikováno v:
O'Neill, K, Einarsson, G, Rowan, S, McIlreavey, L, Lee, A, Lawson, J, Lynch, T, Horsley, A, Bradley, J, Elborn, J & Tunney, M 2020, ' Composition of the airway bacterial community correlates with chest HRCT in adults with bronchiectasis ', Respirology, vol. 25, no. 1, pp. 64-70 . https://doi.org/10.1111/resp.13653
O'neill, K, Einarsson, G G, Rowan, S, Mcilreavey, L, Lee, A J, Lawson, J, Lynch, T, Horsley, A, Bradley, J M, Elborn, J S & Tunney, M M 2019, ' Composition of airway bacterial community correlates with chest HRCT in adults with bronchiectasis ', Respirology . https://doi.org/10.1111/resp.13653
O'neill, K, Einarsson, G G, Rowan, S, Mcilreavey, L, Lee, A J, Lawson, J, Lynch, T, Horsley, A, Bradley, J M, Elborn, J S & Tunney, M M 2019, ' Composition of airway bacterial community correlates with chest HRCT in adults with bronchiectasis ', Respirology . https://doi.org/10.1111/resp.13653
Background and objective In bronchiectasis (BE) not caused by cystic fibrosis, chronic, polymicrobial airway infection contributes to the underlying pathogenesis of disease. There is little information on whether bacterial community composition relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca34f70d3398bd5f567e09ddf100150
https://pure.qub.ac.uk/en/publications/composition-of-the-airway-bacterial-community-correlates-with-chest-hrct-in-adults-with-bronchiectasis(ec0045ef-dcfa-4305-9c03-ea7c3b5f9c26).html
https://pure.qub.ac.uk/en/publications/composition-of-the-airway-bacterial-community-correlates-with-chest-hrct-in-adults-with-bronchiectasis(ec0045ef-dcfa-4305-9c03-ea7c3b5f9c26).html