Peripheral lymphocyte subsets as predicting factors for molecular recurrence after imatinib discontinuation in a phase 2 imatinib discontinuation trial in patients with chronic myeloid leukemia

Autor: Arthur Gomes Oliveira Braga, Katia Borgia Barbosa Pagnano, Marina Dal'Bó Pelegrini Campioni, Ana Beatriz Pascoal Lopes, Gislaine Oliveira Duarte, Konradin Metze, Irene Lorand-Metze

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 46, Iss 3, Pp 268-272 (2024)

Introduction: Treatment-free remission (TFR) is successful in half of the patients with chronic myeloid leukemia who discontinue Imatinib (IM) after sustained molecular response. Methods: In a prospective trial, we used pioglitazone for 3 months befo

Externí odkaz: https://doaj.org/article/844ca4a2161b431180b6697474d2849e

Treatment with dasatinib or nilotinib in chronic myeloid leukemia patients who failed to respond to two previously administered tyrosine kinase inhibitors - a single center experience

Autor: Beatriz Felicio Ribeiro, Eliana C.M. Miranda, Dulcinéia Martins de Albuquerque, Márcia T. Delamain, Gislaine Oliveira-Duarte, Maria Helena Almeida, Bruna Vergílio, Rosana Antunes da Silveira, Vagner Oliveira-Duarte, Irene Lorand-Metze, Carmino A. De Souza, Katia B.B. Pagnano

Publikováno v: Clinics, Vol 70, Iss 8, Pp 550-555 (2015)

OBJECTIVE:To evaluate hematological, cytogenetic and molecular responses as well as the overall, progression-free and event-free survivals of chronic myeloid leukemia patients treated with a third tyrosine kinase inhibitor after failing to respond to

Externí odkaz: https://doaj.org/article/a4a165ab80c94083b9607aae3a73c740

RELATO DE CASO: MUTAÇÃO DA CALRETICULINA ASSOCIADO À POLIGLOBULIA E ELEVAÇÃO DA ERITROPOETINA

Autor: IM Toni, Ibr Filgueiras, Gislaine Oliveira Duarte, Leandro Freitas, Eps Silva, K.B.B. Pagnano, GC Furlin, Irene Lorand-Metze

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 43, Iss, Pp S144-(2021)

Introdução: A Calreticulina (CALR) é uma proteína sinalizadora celular que participa da modulação entre a fase proliferativa e maturativa dos eritroblastos. Sua função está intrinsecamente relacionada à eritropoetina (EPO) e a ativação da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e255b25759c19dd09a3288f9bdd6501
http://www.sciencedirect.com/science/article/pii/S253113792100393X

Evaluation of anemia after long-term treatment with imatinib in chronic myeloid leukemia patients in chronic phase

Autor: Thais Celi Lopes Benevides, Gislaine Oliveira Duarte, Irene Lorand-Metze, Roberto Zulli, Marcia Torresan Delamain, Carmino Antonio De Souza, Priscila de Oliveira Percout, Maria Almeida Dias, Katia B Pagnano, Muriel Silva Moura

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 41, Iss 4, Pp 329-334 (2019)
Hematology, Transfusion and Cell Therapy, Volume: 41, Issue: 4, Pages: 329-334, Published: 25 NOV 2019
Hematology, Transfusion and Cell Therapy

Introduction: The incidence of grade 3–4 anemia was reported to be 3% with imatinib therapy for newly diagnosed chronic myeloid leukemia (CML) in the chronic phase (CP). However, there are few data regarding the causes and the development of anemia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb3a9d2fc21f20940c8e747439c20b6
http://www.sciencedirect.com/science/article/pii/S2531137919300896

Survival differences in multiple myeloma in Latin America and Asia: a comparison involving 3664 patients from regional registries

Autor: Brian G.M. Durie, Juan Ramon Navarro, Gislaine Oliveira Duarte, Chor Sang Chim, Guillermo J. Ruiz-Argüelles, Wenming Chen, Rosane Bittencourt, Kihyun Kim, Jae Hoon Lee, David Gómez-Almaguer, Edvan de Queiroz Crusoe, Angelo Maiolino, Dorotea Fantl, Guillermo Conte, Shang Y.I. Huang, Gracia Martinez, Kazuyuki Shimizu, Wee Joo Chng, Weerasak Nawarawong, Vania Hungria

Publikováno v: Annals of Hematology. 98:941-949

In previous observational studies, we have separately characterized patients with multiple myeloma (MM) both from Latin America (LA) and from Asia. Here, we analyze these two datasets jointly, in order to assess the overall survival (OS) in these two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c081bb6e68fa4b05bce5e95f01ed8a
https://doi.org/10.1007/s00277-019-03602-4