Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Giselle Sek Suan, Nah"'
Autor:
Chelsia Qiuxia Wang, Vaidehi Krishnan, Lavina Sierra Tay, Desmond Wai Loon Chin, Cai Ping Koh, Jing Yuan Chooi, Giselle Sek Suan Nah, Linsen Du, Bindya Jacob, Namiko Yamashita, Soak Kuan Lai, Tuan Zea Tan, Seiichi Mori, Ichiro Tanuichi, Vinay Tergaonkar, Yoshiaki Ito, Motomi Osato
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 767-782 (2014)
The RUNX genes encode transcription factors involved in development and human disease. RUNX1 and RUNX3 are frequently associated with leukemias, yet the basis for their involvement in leukemogenesis is not fully understood. Here, we show that Runx1;R
Externí odkaz:
https://doaj.org/article/3b353b3acf3041a084d54e3e7b53c5e3
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93816 (2014)
The Runx family genes encode transcription factors that play key roles in hematopoiesis, skeletogenesis and neurogenesis and are often implicated in diseases. We describe here the cloning and characterization of Runx1, Runx2, Runx3 and Runxb genes in
Externí odkaz:
https://doaj.org/article/074d692e1b0a4a60b5191675fe4e80eb
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113445 (2014)
The cyclostomes (jawless vertebrates), comprising lampreys and hagfishes, are the sister group of jawed vertebrates (gnathostomes) and are hence an important group for the study of vertebrate evolution. In mammals, three Runx genes, Runx1, Runx2 and
Externí odkaz:
https://doaj.org/article/425f3b5e59df489dba3f16f67459095c
Autor:
Takashi Sonoki, Giselle Sek Suan Nah, Avinash Govind Bahirvani, Alan Prem Kumar, Yoshiaki Ito, Daniel G. Tenen, Hiroki Hosoi, Michelle Meng Huang Mok, Akiko Niibori-Nambu, Takaomi Sanda, Motomi Osato
Publikováno v:
Gene
Epstein-Barr virus nuclear antigens 2 (EBNA2) mediated super-enhancers, defined by in silico data, localize near genes associated with B cell transcription factors including RUNX3. However, the biological function of super-enhancer for RUNX3 gene (se
Autor:
Tuan Zea Tan, Bindya Jacob, Cai Ping Koh, Linsen Du, Motomi Osato, Lavina Sierra Tay, Seiichi Mori, Vaidehi Krishnan, Vinay Tergaonkar, Ichiro Tanuichi, Jing Yuan Chooi, Namiko Yamashita, Yoshiaki Ito, Desmond Wai Loon Chin, Giselle Sek Suan Nah, Soak Kuan Lai, Chelsia Qiuxia Wang
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 767-782 (2014)
SummaryThe RUNX genes encode transcription factors involved in development and human disease. RUNX1 and RUNX3 are frequently associated with leukemias, yet the basis for their involvement in leukemogenesis is not fully understood. Here, we show that
Autor:
M. Sakurai, Gang Huang, Takayoshi Matsumura, Linsen Du, B. Jacob, Giselle Sek Suan Nah, Hideaki Nakajima, Yoshiaki Ito, Xin-Yuan Fu, Toshio Suda, Desmond Wai Loon Chin, Tomomasa Yokomizo, Motomi Osato
Publikováno v:
Blood Cancer Journal
RUNX1/AML1 is among the most commonly mutated genes in human leukemia. Haploinsufficiency of RUNX1 causes familial platelet disorder with predisposition to myeloid malignancies (FPD/MM). However, the molecular mechanism of FPD/MM remains unknown. Her
Autor:
Cai Ping, Koh, Cherry Ee Lin, Ng, Giselle Sek Suan, Nah, Chelsia Qiuxia, Wang, Vinay, Tergaonkar, Takayoshi, Matsumura, Tomomasa, Yokomizo, Toshio, Suda, Motomi, Osato
Publikováno v:
Histology and histopathology. 30(6)
There has been considerable interest in identifying a cis-regulatory element that targets gene expression to stem cells. Such an element, termed stem cell enhancer, holds the promise of providing important insights into the transcriptional programs r
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e113445 (2014)
PLoS ONE, Vol 9, Iss 11, p e113445 (2014)
The cyclostomes (jawless vertebrates), comprising lampreys and hagfishes, are the sister group of jawed vertebrates (gnathostomes) and are hence an important group for the study of vertebrate evolution. In mammals, three Runx genes, Runx1, Runx2 and
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e93816 (2014)
PLoS ONE, Vol 9, Iss 4, p e93816 (2014)
The Runx family genes encode transcription factors that play key roles in hematopoiesis, skeletogenesis and neurogenesis and are often implicated in diseases. We describe here the cloning and characterization of Runx1, Runx2, Runx3 and Runxb genes in
Publikováno v:
Blood cells, moleculesdiseases. 44(4)
In multicellular organisms, terminally differentiated cells of most tissues are short-lived and therefore require constant replenishment from rapidly dividing stem cells for homeostasis and tissue repair. For the stem cells to last throughout the lif