Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Giselle Sanchez Guerrero"'
Autor:
Giselle Sanchez-Guerrero, David S. Umbaugh, Abhay A. Ramachandran, Antonio Artigues, Hartmut Jaeschke, Anup Ramachandran
Publikováno v:
Livers, Vol 4, Iss 1, Pp 15-30 (2023)
The adenosine A2B receptor (A2BAR) is a member of a family of G-protein coupled receptors (GPCRs), which has a low affinity for adenosine and is now implicated in several pathophysiological conditions. We have demonstrated the beneficial effects of A
Externí odkaz:
https://doaj.org/article/ceb664350c874129ba3fca2decf832c9
Autor:
Hartmut Jaeschke, Olamide B. Adelusi, Jephte Y. Akakpo, Nga T. Nguyen, Giselle Sanchez-Guerrero, David S. Umbaugh, Wen-Xing Ding, Anup Ramachandran
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3740-3755 (2021)
Acetaminophen (APAP) is a widely used analgesic and antipyretic drug, which is safe at therapeutic doses but can cause severe liver injury and even liver failure after overdoses. The mouse model of APAP hepatotoxicity recapitulates closely the human
Externí odkaz:
https://doaj.org/article/bd69267488f147738d37afb49958d353
Autor:
Ranjeet S. Kalsi, Alina Ostrowska, Adam Olson, Mubina Quader, Melvin Deutsch, Norma J. Arbujas-Silva, Jen Symmonds, Alejandro Soto-Gutierrez, John J. Crowley, Miguel Reyes-Mugica, Giselle Sanchez-Guerrero, Hartmut Jaeschke, Bruce P. Amiot, Marilia Cascalho, Scott L. Nyberg, Jeffrey L. Platt, Edgar N. Tafaleng, Ira J. Fox
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Acute hepatic failure is associated with high morbidity and mortality for which the only definitive therapy is liver transplantation. Some fraction of those who undergo emergency transplantation have been shown to recover native liver function when t
Externí odkaz:
https://doaj.org/article/4a6dde84b6564e42889da8c6dbe04394
Autor:
Nga T. Nguyen, David S. Umbaugh, Sawyer Smith, Olamide B. Adelusi, Giselle Sanchez-Guerrero, Anup Ramachandran, Hartmut Jaeschke
Publikováno v:
Archives of Toxicology. 97:1397-1412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::422eae9dc9a3c2ad9d43474cd0387f63
https://doi.org/10.1007/s00204-023-03478-4
https://doi.org/10.1007/s00204-023-03478-4
Autor:
Nga T Nguyen, David S Umbaugh, Eileen L Huang, Olamide B Adelusi, Giselle Sanchez Guerrero, Anup Ramachandran, Hartmut Jaeschke
Publikováno v:
Toxicol Sci
Acetaminophen (APAP) overdose is the main cause of acute liver failure in Western countries. The mechanism of APAP hepatotoxicity is associated with centrilobular necrosis which initiates infiltration of neutrophils, monocytes, and other leukocytes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52742d4d3f6f9e4971eac5d30062edb6
https://doi.org/10.1093/toxsci/kfac057
https://doi.org/10.1093/toxsci/kfac057
Autor:
Claudia Robles-Planells, Sofia A. Michelson, Javier Mena, Daniela Escrig, Juan L. Rojas, Giselle Sanchez-Guerrero, Ronny Hernández, Carlos Barrera-Avalos, Leonel E. Rojo, Daniela Sauma, Alexis M. Kalergis, Mónica Imarai, Ricardo Fernández, Carolina A. Robles, Elías Leiva-Salcedo, Rocio Santander, Alejandro Escobar, Claudio Acuña-Castillo
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Melanoma immunotherapy, specifically the autotransplant of dendritic cells charged with tumors antigens, has shown promising results in clinical trials. The positive clinical effects of this therapy have been associated to increased Th17 response and
Externí odkaz:
https://doaj.org/article/1ee59b96ff124ad68a8a218a86c6a7ef
Autor:
David Umbaugh, Nga Nguyen, Giselle Sanchez Guerrero, Cecilia Villanueva, Bruno Hagenbuch, Anup Ramachandran, Hartmut Jaeschke
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Toxicology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1d3d09ffa27a54f13d921440cc577b2
https://doi.org/10.1124/jpet.122.294240
https://doi.org/10.1124/jpet.122.294240
Autor:
Subhrajit Saha, Chris Lominska, Terance T. Tsue, Bruce F. Kimler, Giselle Sanchez-Guerrero, Randal Riha, Payel Bhanja, Dhrubajyoti Nag
Purpose:The radiosensitivity of the normal intestinal epithelium is the major limiting factor for definitive radiotherapy against abdominal malignancies. Radiosensitizers, which can be used without augmenting radiation toxicity to normal tissue, are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c6376d12abeb9758bab96cfadd1355
https://doi.org/10.1158/1078-0432.c.6527657
https://doi.org/10.1158/1078-0432.c.6527657
Autor:
Subhrajit Saha, Chris Lominska, Terance T. Tsue, Bruce F. Kimler, Giselle Sanchez-Guerrero, Randal Riha, Payel Bhanja, Dhrubajyoti Nag
Supplement FigureS4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4a6e7e99a34f49502341e11ef08ee4
https://doi.org/10.1158/1078-0432.22470695.v1
https://doi.org/10.1158/1078-0432.22470695.v1
Autor:
Subhrajit Saha, Chris Lominska, Terance T. Tsue, Bruce F. Kimler, Giselle Sanchez-Guerrero, Randal Riha, Payel Bhanja, Dhrubajyoti Nag
Supplement Figure S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0611cb8352c46c944d4e8c7590c1a5b8
https://doi.org/10.1158/1078-0432.22470704.v1
https://doi.org/10.1158/1078-0432.22470704.v1