Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Giselle E. Yeung"'
Autor:
Yuwen Xue, Giselle E. Yeung, Ping Chieh Chou, Huiling Yang, Janice Santiago, Mong Hong Lee, Mo Liu, Liem Phan, Jian Chen, Sai Ching J. Yeung, Ruiying Zhao, Hyun Ho Choi
Publikováno v:
Cell Cycle. 11:4181-4190
HER2/neu oncogene is frequently overexpressed in various types of cancer, and the (PI3K)-Akt signaling pathway is often activated in HER2-overexpressing cancer cells. CSN6, subunit 6 of the COP9 signalosome complex, is pivotal in regulating MDM2 to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4308c92a4fcd1422111871ccb7d312
https://doi.org/10.4161/cc.22413
https://doi.org/10.4161/cc.22413
Autor:
Huamin Wang, Ping Chieh Chou, Yun Chih Hsieh, Guermarie Velazquez-Torres, Jiun Sheng Chen, Shih-Lan Hsu, Jian Chen, Giselle E. Yeung, Liem Phan, Zhongguo Zhou, Sai Ching J. Yeung, Chun Hui Su, Ji Hyun Shin, Christopher Gully, Edward Wang, Yuwen Xue, Yi Qiao, Tattym Shaikenov, Kazufumi Ohshiro, Chieh Tseng, Hua Wang, Mong Hong Lee, Ruiying Zhao, Sean M. Post, Hyun Ho Choi, Enrique Fuentes-Mattei
Publikováno v:
Nature communications
Summary Cullin-RING ubiquitin ligases (CRL) are critical in ubiquitinating Myc, while COP9 signalosome (CSN) controls neddylation of Cullin in CRL. The mechanistic link between Cullin neddylation and Myc ubiquitination/degradation is unclear. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4c75b579706e02866df832f7117eec
https://doi.org/10.1038/ncomms6384
https://doi.org/10.1038/ncomms6384