Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Giselle Chamberlain"'
Autor:
Sandra Sacre, Albert Jaxa-Chamiec, Caroline M. R. Low, Giselle Chamberlain, Cathy Tralau-Stewart
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Antidepressants are increasingly recognized to have anti-inflammatory properties in addition to their ability to treat major depressive disorders. To explore if engagement of 5-hydroxytryptamine (5-HT) receptors was required for the anti-inflammatory
Externí odkaz:
https://doaj.org/article/e03023c2da2f45bea40af4e459cb2710
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25663 (2011)
Mesenchymal stem cells (MSCs) have anti-inflammatory and immunosuppressive properties and may be useful in the therapy of diseases such as arteriosclerosis. MSCs have some ability to traffic into inflamed tissues, however to exploit this therapeutica
Externí odkaz:
https://doaj.org/article/1d5e0c67c87c4447afced72606226416
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2934 (2008)
Mesenchymal stem cells (MSCs) are non-haematopoeitic, stromal cells that are capable of differentiating into mesenchymal tissues such as bone and cartilage. They are rare in bone marrow, but have the ability to expand many-fold in culture, and retain
Externí odkaz:
https://doaj.org/article/8a5e38c450954208ad2cbde0d7045a16
Autor:
Neil A. Harrison, Ryan S Thwaites, Giselle Chamberlain, Sarah Unterberger, K M Jordan, Sandra Sacre, Henry Gray, Kevin A. Davies
Publikováno v:
Rheumatology (Oxford, England)
Objective Cartilage and bone damage in RA are associated with elevated IL-1β. The effects of IL-1β can be reduced by biological therapies that target IL-1β or TNF-α. However, the mechanisms responsible for increased IL-1β and the effect of anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b74dabfc013eaed21ac01b04afe45b2
https://doi.org/10.1093/rheumatology/keab162
https://doi.org/10.1093/rheumatology/keab162
Autor:
Karen Walker-Bone, Kevin A. Davies, Sarah Unterberger, Giselle Chamberlain, Sandra Sacre, Ryan S Thwaites
Publikováno v:
Rheumatology (Oxford, England)
Objective RA is an autoimmune inflammatory joint disease. Both RF and ACPA are associated with more progressive disease and higher levels of systemic inflammation. Monocyte activation of toll-like receptors (TLRs) by endogenous ligands is a potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42ce638f91be3145c4d001b97fb0cb1
https://pubmed.ncbi.nlm.nih.gov/32594150
https://pubmed.ncbi.nlm.nih.gov/32594150
Autor:
Fionula M. Brennan, Bernard Gregory, Matthew Stephens, Giselle Chamberlain, P.M. Stott, Sandra Sacre, Alexandra Lo
Publikováno v:
European Journal of Immunology. 46:772-781
Toll-like receptors (TLRs) are innate immune receptors that respond to both exogenous and endogenous stimuli and are suggested to contribute to the perpetuation of chronic inflammation associated with rheumatoid arthritis (RA). In particular, the end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb68c08c3d4dad2d488752723841c3f
https://doi.org/10.1002/eji.201546123
https://doi.org/10.1002/eji.201546123
Autor:
Laurence B. Peterson, Kara Hunter, Linda S. Wicker, Giselle Chamberlain, Pere Santamaria, Jun Yamanouchi, Paul A. Lyons, Maria-Carmen Puertas, Daniel B. Rainbow, Joan Verdaguer
Publikováno v:
Diabetes
OBJECTIVEThe ∼45-cM insulin-dependent diabetes 9 (Idd9) region on mouse chromosome 4 harbors several different type 1 diabetes–associated loci. Nonobese diabetic (NOD) mice congenic for the Idd9 region of C57BL/10 (B10) mice, carrying antidiabeto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4c048626f993d9f1fc3aa7231e65fe
https://doi.org/10.2337/db09-0648
https://doi.org/10.2337/db09-0648
Autor:
Sue Liu, Raymond A. Sobel, Lalitha Vijayakrishnan, Laurence B. Peterson, Manabu Araki, Denise Chung, Daniel B. Rainbow, Mohamed Oukka, Vijay K. Kuchroo, Linda S. Wicker, Valerie E S Garner, Giselle Chamberlain, Arlene H. Sharpe, Kara Hunter
Publikováno v:
The Journal of Immunology. 183:5146-5157
Idd5.1 regulates T1D susceptibility in nonobese diabetic (NOD) mice and has two notable candidate genes, Ctla4 and Icos. Reduced expression of one of the four CTLA-4 isoforms, ligand-independent CTLA-4 (liCTLA-4), which inhibits in vitro T cell activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcc69a51b4be0a56ec0aeec1af9fc38c
https://doi.org/10.4049/jimmunol.0802610
https://doi.org/10.4049/jimmunol.0802610
Publikováno v:
Stem Cells. 25:2739-2749
MSCs are nonhematopoietic stromal cells that are capable of differentiating into, and contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle, ligament, tendon, and adipose. MSCs are rare in bone marrow, representing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc78728e5b19b58e00e04e0263ecd7c
https://doi.org/10.1634/stemcells.2007-0197
https://doi.org/10.1634/stemcells.2007-0197
Autor:
William E. B. Johnson, Sally Roberts, Wagih El Masri, B A Ashton, Giselle Chamberlain, Karina T. Wright, Aheed Osman
Publikováno v:
Biochemical and Biophysical Research Communications. 354:559-566
In animal models, transplantation of bone marrow stromal cells (MSC) into the spinal cord following injury enhances axonal regeneration and promotes functional recovery. How these improvements come about is currently unclear. We have examined the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b30947b2fd39b4bbc76dd1fe18b3e9b
https://doi.org/10.1016/j.bbrc.2007.01.013
https://doi.org/10.1016/j.bbrc.2007.01.013