Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Giselle, Singer"'
Autor:
Megan H. Trager, Emanuelle Rizk, Sharon Rose, Kuixi Zhu, Branden Lau, Benjamin T. Fullerton, Jaya Pradhan, Michael Moore, Ayush C. Srivastava, Giselle Singer, Robyn Gartrell, Rui Chang, Larisa J. Geskin, Yvonne M. Saenger, Gary Goldenberg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The presence of actinic keratoses (AKs) increases a patient’s risk of developing squamous cell carcinoma by greater than six-fold. We evaluated the effect of topical treatment with imiquimod on the tumor microenvironment by measuring trans
Externí odkaz:
https://doaj.org/article/6bb5791204724714b50998aaf52add66
Autor:
Michael Angelov, Giselle Singer, Emma Guttman-Yassky, Mashkura Chowdhury, Celina Dubin, Sumanth Chennareddy, Grace Kimmel, Yeriel Estrada, Joseph Han, Ning Zhang, Jacob W. Glickman, Ana B. Pavel, Jesús Gay-Mimbrera, Andrew Y. Zheng, Juan Ruano Ruiz, Ester Del Duca, James G. Krueger, Dante Dahabreh
Publikováno v:
Journal of the American Academy of Dermatology. 86:551-562
Frontal fibrosing alopecia (FFA) is a progressive, scarring alopecia of the frontotemporal scalp that poses a substantial burden on quality of life. Large-scale global profiling of FFA is lacking, preventing the development of effective therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f75846f42cb0a81425c5d678cf9887
https://doi.org/10.1016/j.jaad.2021.05.016
https://doi.org/10.1016/j.jaad.2021.05.016
Autor:
Rachel Lefferdink, Stephanie M. Rangel, Margot Chima, Erin Ibler, Ana B. Pavel, HeeJin Kim, Benedict Wu, Hajar Abu-Zayed, Jianni Wu, Kathryn Jackson, Giselle Singer, Keith A. Choate, Emma Guttman-Yassky, Amy S. Paller
Publikováno v:
Archives of Dermatological Research. 315:305-315
Treatment of congenital ichthyoses primarily focuses on reversing skin scaling and is not pathogenesis based. Recent studies showed Th17 immune skewing, as in psoriasis, across the spectrum of ichthyosis, suggesting that targeting this pathway might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5aedae7285cfc742f9f03e38e3552f
https://doi.org/10.1007/s00403-022-02325-3
https://doi.org/10.1007/s00403-022-02325-3
Autor:
Antonio Sanin, Alyssa Gontzes, Diana Gruenstein, Emma Guttman-Yassky, Jacob W. Glickman, Olga Marushchak, Celina Dubin, Nancy Wei, Alexandra K. Golant, Ana B. Pavel, Danielle Baum, Giselle Singer, Daniela Mikhaylov, Mark Lebwohl, Benjamin Ungar
Publikováno v:
The Journal of Allergy and Clinical Immunology. in Practice
Background In the SARS-CoV-2/COVID-19 pandemic, we need to understand the impact of immunomodulatory medications on COVID-19 symptom severity in patients with inflammatory diseases, including the type 2/Th2 polarized skin disease, atopic dermatitis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d0ea9280b9bbfcf92e982cdc772d63
https://doi.org/10.1016/j.jaip.2021.10.050
https://doi.org/10.1016/j.jaip.2021.10.050
Autor:
Hee Jin Kim, Grace Kimmel, Jennifer Bares, Soo Jung Kim, Giselle Singer, Alex Yaroshinsky, Margot Chima, Mark Lebwohl, Jerry Bagel
Publikováno v:
SKIN The Journal of Cutaneous Medicine. 5:524-529
Background: Brodalumab is an interleukin-17 receptor A antagonist approved for the treatment of moderate-to-severe plaque psoriasis. Our prior publication reported significant disease improvement with brodalumab in psoriasis patients who had previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e3884d555f30857c4e21315e828bcaa
https://doi.org/10.25251/skin.5.5.10
https://doi.org/10.25251/skin.5.5.10
Autor:
Mark Lebwohl, Emma Guttman-Yassky, Giselle Singer, Jason E. Hawkes, Yael Renert-Yuval, Jennifer Bares, Margot Chima, Patricia Gilleaudeau, Sandra Garcet, Ana B. Pavel, James G. Krueger, Mary Sullivan-Whalen
Publikováno v:
Allergy
BACKGROUND Treatments for alopecia areata (AA) patients with extensive scalp hair loss are limited, and recent evidence supports a role for type 2 T-cell (Th2)-immune response in AA. Dupilumab, a monoclonal antibody inhibiting Th2 signaling, approved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84007341959e7315261390e878bc7986
https://doi.org/10.1111/all.15071
https://doi.org/10.1111/all.15071
Autor:
Kuixi Zhu, Ayush C. Srivastava, Robyn D. Gartrell, Yvonne M. Saenger, Larisa J. Geskin, Branden Lau, Megan H. Trager, Michael Moore, Benjamin T. Fullerton, Sharon Rose, Rui Chang, Jaya Sarin Pradhan, Emanuelle M. Rizk, Gary Goldenberg, Giselle Singer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
The presence of actinic keratoses (AKs) increases a patient’s risk of developing squamous cell carcinoma by greater than six-fold. We evaluated the effect of topical treatment with imiquimod on the tumor microenvironment by measuring transcriptomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2600acb44254be7d678bd701299c0f8c
https://doaj.org/article/6bb5791204724714b50998aaf52add66
https://doaj.org/article/6bb5791204724714b50998aaf52add66
Autor:
Randall Li, Giselle Singer, John K Nia, Ana B. Pavel, Peter W Hashim, Hee Jin Kim, Emma Guttman-Yassky, Xiangyu Peng, Danielle Baum, Yasaman Mansouri, Anjali S. Vekaria, Hui Xu, Grace Kimmel, Yeriel Estrada, Margot Chima, Benjamin Ungar, Mark Taliercio
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:394-397
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb6cc2380c5e8b84674939d05e80bef1
https://doi.org/10.1016/j.jaci.2020.04.055
https://doi.org/10.1016/j.jaci.2020.04.055
Autor:
Matthew Gagliotti, Tinley Chen, John K Nia, Christopher J. Yao, Margot Chima, Jordan Genece, Peter W Hashim, Grace Kimmel, H. Kim, Mark Lebwohl, Giselle Singer, Danielle Baum, Jennifer Bares
Publikováno v:
Journal of the American Academy of Dermatology. 82:360-365
Background Psoriasis of the intertriginous, anogenital, and facial regions remains a therapeutic challenge, with current algorithms lacking a topical agent that exhibits both high efficacy and minimal side effects. Objective To assess the safety and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341742504c0b0ff6da06aca1ad218059
https://doi.org/10.1016/j.jaad.2019.06.1288
https://doi.org/10.1016/j.jaad.2019.06.1288
Autor:
Dante Dahabreh, James G. Krueger, Giselle Singer, Joseph Han, Celina Dubin, Ning Zhang, Yeriel Estrada, Ester Del Duca, Ana B. Pavel, Jacob W. Glickman, Grace Kimmel, Emma Guttman-Yassky
Publikováno v:
AllergyREFERENCES. 76(10)
BACKGROUND Alopecia areata (AA) is characterized by immune dysregulation in both scalp and blood, but a large-scale approach establishing biomarkers of AA incorporating both scalp tissue and serum compartments is lacking. We aimed to characterize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86a28d7ed2c75c900774a7c31ff233b
https://pubmed.ncbi.nlm.nih.gov/33721346
https://pubmed.ncbi.nlm.nih.gov/33721346