Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Gisella, Terre'Blanche"'
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Objective To ensure reproducibility in biomedical research, the biological variable sex must be reported; yet a reason for using male (instead of female) rodents is seldom given. In our search for novel adenosine receptor ligands, our resear
Externí odkaz:
https://doaj.org/article/ce0adf95f77e4ce99f2d4a5ada522cf0
Autor:
Olakunle Sanni, Gisella Terre’Blanche
Publikováno v:
BMC Endocrine Disorders, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background/Aim Recent research suggests that adenosine receptors (ARs) influence many of the metabolic abnormalities associated with diabetes. A non-xanthine benzylidene indanone derivative 2-(3,4-dihydroxybenzylidene)-4-methoxy-2,3-dihydro-
Externí odkaz:
https://doaj.org/article/e0213e3af3fe42ffacaad303110b64b0
Publikováno v:
Medicinal Chemistry Research. 31:1277-1297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c78cf97ddd0af0cbd1778b5e36b9e58e
https://doi.org/10.1007/s00044-022-02908-9
https://doi.org/10.1007/s00044-022-02908-9
Autor:
Chrisna Matthee, Gisella Terre’Blanche, Helena D. Janse van Rensburg, Janine Aucamp, Lesetja J. Legoabe
Publikováno v:
Chemical Biology & Drug Design. 99:416-437
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::919f1c23ce4841e506edb7faa026856b
https://doi.org/10.1111/cbdd.13999
https://doi.org/10.1111/cbdd.13999
Autor:
Nadia Janse van Vuuren, Lesetja J. Legoabe, Helena D. Janse van Rensburg, Gisella Terre’Blanche
Publikováno v:
Molecular Diversity. 26:2211-2220
In a pilot study, eleven pyrrolopyridine and pyrrolopyrimidine derivatives (specifically, 7-azaindole and 7-deazapurine derivatives) were synthesised by Suzuki cross-coupling reactions and evaluated via radioligand binding assays as potential adenosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1023c0073211a314bc705da1c1e2d848
https://doi.org/10.1007/s11030-021-10327-y
https://doi.org/10.1007/s11030-021-10327-y
Publikováno v:
Molecular Diversity. 26:1779-1821
Adenosine receptors (ARs) are ubiquitously distributed throughout the mammalian body where they are involved in an extensive list of physiological and pathological processes that scientists have only begun to decipher. Resultantly, AR agonists and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117d589f6bee92c9668a5281aaf1e584
https://doi.org/10.1007/s11030-021-10257-9
https://doi.org/10.1007/s11030-021-10257-9
Objective: To ensure reproducibility in biomedical research, the biological variable sex must be reported; yet a reason for using male (instead of female) rodents is seldom given. In our search for novel adenosine receptor ligands, our research group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58c6984b43159f498f7d3586a46aa7d
https://doi.org/10.21203/rs.3.rs-1953772/v1
https://doi.org/10.21203/rs.3.rs-1953772/v1
Autor:
Gaofenngwe Nkomba, Gisella Terre'Blanche, Helena Dorathea Janse van Rensburg, Lesetja J. Legoabe
Due to the implication of adenosine in seizure suppression, adenosine-based therapies such as adenosine receptor (AR) agonists have been investigated. This study aimed at investigating thieno[2,3-b]pyridine derivatives as non-nucleoside A1 agonists t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::208f20ec9bf4b9c60745ad8c95cb4957
https://doi.org/10.21203/rs.3.rs-1500396/v1
https://doi.org/10.21203/rs.3.rs-1500396/v1
Publikováno v:
Chemicke Zvesti
To identify novel adenosine receptor (AR) ligands based on the chalcone scaffold, herein the synthesis, characterization and in vitro and in silico evaluation of 33 chalcones (15–36 and 37–41) and structurally related compounds (42–47) are repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e00cda28f192e0d5f74dfa083ac5d49
http://europepmc.org/articles/PMC7670844
http://europepmc.org/articles/PMC7670844
Autor:
Chrisna, Matthee, Gisella, Terre'Blanche, Helena D, Janse van Rensburg, Janine, Aucamp, Lesetja J, Legoabe
Publikováno v:
Chemical biologydrug designREFERENCES. 99(3)
Over the past few years, great progress has been made in the development of high-affinity adenosine A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dea20d75e02e896674dbd369f3ae7e08
https://pubmed.ncbi.nlm.nih.gov/34878728
https://pubmed.ncbi.nlm.nih.gov/34878728