Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Giseli Capaci Rodrigues"'
Autor:
Lorraine Martins Rocha Orlando, Leonardo da Silva Lara, Guilherme Curty Lechuga, Giseli Capaci Rodrigues, Omar Ginoble Pandoli, Druval Santos de Sá, Mirian Claudia de Souza Pereira
Publikováno v:
Biology, Vol 12, Iss 9, p 1222 (2023)
Chagas disease therapy still relies on two nitroderivatives, nifurtimox and benznidazole (Bz), which have important limitations and serious adverse effects. New therapeutic alternatives for this silent disease, which has become a worldwide public hea
Externí odkaz:
https://doaj.org/article/1f983e5646b441299b7b5c4305f3522d
Discovery of novel drugs for Chagas disease: is carbonic anhydrase a target for antiprotozoal drugs?
Autor:
Alane Beatriz Vermelho, Giseli Capaci Rodrigues, Alessio Nocentini, Felipe R. P. Mansoldo, Claudiu T. Supuran
Publikováno v:
Expert Opinion on Drug Discovery. 17:1147-1158
Carbonic anhydrase (CA) arose significant interest as a potential new target for Chagas disease since its discovery inWe discuss the positive and negative aspects ofThe search for new targets and drugs is a significant challenge worldwide, and TcCA i
Publikováno v:
Revista de Ensino de Engenharia. 39:137-146
O grande desafio da educacao e expandir o ambiente de aprendizagem para alem da sala de aula. Alunos de engenharia receberam o desafio de desenvolver um prototipo de um equipamento hidraulico com algum aspecto inovador. A turma se dividiu em grupos p
Autor:
Alane Beatriz Vermelho, Verônica Cardoso, Felipe Raposo Passos Mansoldo, Claudiu T. Supuran, Sabrina Martins Lage Cedrola, Igor Almeida Rodrigues, Giseli Capaci Rodrigues
Publikováno v:
Topics in Medicinal Chemistry ISBN: 9783031068492
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e3624a5517827b06c7aabc3a4b56baf
https://doi.org/10.1007/7355_2022_144
https://doi.org/10.1007/7355_2022_144
Autor:
Alane Beatriz Vermelho, Verônica Cardoso, Felipe Raposo Passos Mansoldo, Claudiu T. Supuran, Sabrina Martins Lage Cedrola, Igor Almeida Rodrigues, Giseli Capaci Rodrigues
Publikováno v:
Topics in Medicinal Chemistry ISBN: 9783031068492
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd057e77661600cc7433a727081c8e12
https://doi.org/10.1007/7355_2021_143
https://doi.org/10.1007/7355_2021_143
Publikováno v:
Expert Opinion on Drug Discovery. 15:145-158
Introduction: Chagas disease (CD) is a neglected disease caused by the protozoan parasite Trypanosoma cruzi. In terms of novel drug discovery, there has been no progress since the 1960s with the sa...
Autor:
Claudiu T. Supuran, Igor Rodrigues Almeida, Alcino Palermo de Aguiar, Mirian Claudia de Souza Pereira, Giseli Capaci Rodrigues, Alane Beatriz Vermelho, Dayanne da Rocha de Menezes, Claudia M. Calvet
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 31:964-973
This work describes the antitrypanocidal activity of two hydroxamic acid derivatives containing o-ethoxy (HAD1) and p-ethoxy (HAD2) as substituent in the aromatic ring linked to the isoxazoline ring. HAD1 and HAD2 induced a significant reduction in t
Autor:
Luciana Troca Dantas, Bárbara Cristina Mathias dos Santos, Giseli Capaci Rodrigues, Chang Kuo Rodrigues
Publikováno v:
Ensino, Saude e Ambiente. 10
Este trabalho, realizado pelo Grupo de Pesquisa e Investigação no Ensino de matemática e Ciências, na base do CNPq e validado pela Universidade do Grande Rio, apresenta questões pertinentes a estratégias de ensino de educação financeira nos a
Autor:
Giseli Capaci Rodrigues, Alcino Palermo de Aguiar, Andrew Macrae, Ana Cristina Nogueira de Melo, Alane Beatriz Vermelho, Joao Lidio da Silva Goncalves Vianez
Publikováno v:
Current Enzyme Inhibition. 6:183-194
Chagas disease, caused by Trypanosoma cruzi, is one of the neglected parasitic tropical diseases affecting thir- teen million people annually. At present, there are only two compounds used in the clinical treatment to this disease and they were intro
Autor:
Thaïs Souto-Padrón, Thiago Luiz Alves e Silva, Angela H. Lopes, Felipe A. Dias, Luciana T. Zimmermann, Giseli Capaci Rodrigues, Marta T. Gomes, Alane Beatriz Vermelho
Publikováno v:
The Open Parasitology Journal. 4:30-59
Trypanosomatids cause many diseases in and on animals (including humans) and plants. Altogether, about 37 million people are infected with Trypanosoma brucei (African sleeping sickness), Trypanosoma cruzi (Chagas disease) and Leishmania species (dist