Výsledky vyhledávání - "Gisele de Freitas Gauze"

Akademický článek

Anticholinesterase activity of β-carboline-1,3,5-triazine hybrids

Autor: Paula Baréa, Valéria Aquilino Barbosa, Diego Alberto dos Santos Yamazaki, Carla Maria Beraldi Gomes, Claudio R. Novello, Willian Ferreira da Costa, Gisele de Freitas Gauze, Maria Helena Sarragiotto

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)

Abstract The β-carboline-1,3,5-triazine hydrochlorides 8-13 were evaluated in vitro against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). The analysed compounds were selective to BuChE, with IC50 values in the range from 1.0-18.8 µ

Externí odkaz: https://doaj.org/article/9e8e8ca5c07e4fe193f7f8cb6edeb0d1

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Akademický článek

Proteomic Response of Paracoccidioides brasiliensis Exposed to the Antifungal 4-Methoxynaphthalene-N-acylhydrazone Reveals Alteration in Metabolism

Autor: Lívia do Carmo Silva, Kleber Santiago Freitas e Silva, Olívia Basso Rocha, Katheryne Lohany Barros Barbosa, Andrew Matheus Frederico Rozada, Gisele de Freitas Gauze, Célia Maria de Almeida Soares, Maristela Pereira

Publikováno v: Journal of Fungi, Vol 9, Iss 1, p 66 (2022)

Background: Paracoccidioidomycosis is a neglected mycosis with a high socioeconomic impact that requires long-term treatment with antifungals that have limitations in their use. The development of antifungals targeting essential proteins that are pre

Externí odkaz: https://doaj.org/article/41126eb8e4744693b7e872bd2446153c

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Heterologous overexpression and characterization of homoserine dehydrogenase from Paracoccidioides brasiliensis

Autor: Jessyka Lima Santos, Elisângela Andrade Ângelo, Gisele de Freitas Gauze, Flavio Augusto Vicente Seixas, Fernanda Canduri

Publikováno v: Biochimie. 211:87-95

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c59bea332ea6648eee32e86f9364113e
https://doi.org/10.1016/j.biochi.2023.03.003

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Exploration of essential oil from Psychotria poeppigiana as an anti-hyperalgesic and anti-acetylcholinesterase agent: Chemical composition, biological activity and molecular docking

Autor: Anelise Samara Nazari Formagio, Wagner Vilegas, Carla Roberta Ferreira Volobuff, Candida Aparecida Leite kassuya, Claudia Andrea Lima Cardoso, Zefa Valdevina Pereira, Rosilda Mara Mussury Franco Silva, Diego Alberto dos Santos Yamazaki, Gisele de Freitas Gauze, Jane Manfron, Janaine Alberto Marangoni

Publikováno v: Journal of ethnopharmacology. 296

Leaves from Psychotria poeppigiana Müll. Arg. (accepted as Palicourea tomentosa (Aubl.) Borhidi), Rubiaceae, has traditionally been used in medicine for treatments of inflammation and pain; Synonymously, Cephaelis elata for the treatment of dementia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfb59996b3d2b5a2db51fae24e6e9ab
https://pubmed.ncbi.nlm.nih.gov/35358624

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Conformational Isomerism of 3-Chalcogenomethyl

Autor: Ulisses Zonta, de Melo, Cleverton de Souza, Fernandes, Camila Botin, Francisco, Tânia Cristina, Carini, Gisele de Freitas, Gauze, Roberto, Rittner, Ernani Abicht, Basso

Publikováno v: The journal of physical chemistry. A. 124(41)

A conformational analysis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e386bf8dd22e2c9ba0707e7e36564cc7
https://pubmed.ncbi.nlm.nih.gov/32960599

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Synthetic Application of New Enaminodiketone: Regioespecific Synthesis of Aza-Heterocycles

Autor: Gisele De Freitas Gauze Bandoch, Davana S. Gonçalves, Camila S. S. Tozatti, Fernanda A. Rosa, Daniela H. Arita, Michael J. V. da Silva

Publikováno v: Proceedings of the 15th Brazilian Meeting on Organic Synthesis Proceedings.

and pyridazinones 2 , have become increasingly important because they have proven to be extremely bioactive moieties. The synthesis of nitrogencontaining heterocyclic compounds has been well explored by reacting of blocks precursors enaminodiketones

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6aee666b12698033613c6acaf06917d
https://doi.org/10.5151/chempro-15bmos-bmos2013_2013101145054

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Estudo por espectroscopia de RMN e cálculos teóricos de derivados da norcânfora e de ditianos

Autor: Bandoch, Gisele de Freitas Gauze

Publikováno v: Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
Universidade Estadual de Maringá (UEM)
instacron:UEM

The present work reports the study of the mains parameters of NMR spectroscopy in norcamphor and dithiane derivatives. In the first part the results of synthesis, separation and purification of 3-exo-hidroxinorcânfora e 3-exo e 3-endo-metiltio e met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::d40fbbbc21cc65f5ae0a73eaeb3ebac9
http://repositorio.uem.br:8080/jspui/handle/1/3926

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Síntese, modelagem molecular e avaliação da atividade anticolinesterásica de N,N-dimetilcarbamatos de cicloexila 3-arilaminossubstituídos

Autor: Yamazaki, Diego Alberto dos Santos

Publikováno v: Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
Universidade Estadual de Maringá (UEM)
instacron:UEM

The carbamate group has great pharmacological importance as a cholinesterase inhibitor and in the treatment of Alzheimer's disease. The present study describes the synthesis, conformational analysis, assessment of the anticholinesterase activity and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::48d99fab80cdaf77694626e6588c6139
http://repositorio.uem.br:8080/jspui/handle/1/4648

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Synthesis of biological evaluation of new aminoflavones designed as potential, anticholinesterases for Alzheimers disease treatment

Autor: Karinne Esteves Prado

Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP

A doença de Alzheimer (DA) é um distúrbio neurodegenerativo caracterizado pela perda progressiva de memória e por deficiências cognitivas. As principais características apresentadas pelos pacientes com DA são as placas senis, os emaranhados ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de8501ae2c4107ec31d3cf42f39d838

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Otimização de compostos inibidores da tioredoxina redutase de Candida

Autor: Capoci, Isis Regina Grenier

Publikováno v: Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
Universidade Estadual de Maringá (UEM)
instacron:UEM

Orientadora: Profª. Drª. Terezinha Inez Estivalet Svidzinski Coorientadora: Profª. Drª. Érika Seki Kioshima Tese (doutorado em Biociências e Fisiopatologia) - Universidade Estadual de Maringá, 2018 RESUMO: Nas últimas décadas as doenças fú

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::08ca77b7652be0d900cba6db4ee6a193
http://repositorio.uem.br:8080/jspui/handle/1/5966

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