Výsledky vyhledávání - "Gisele Vanessa Baracho"

Immunophenotypic and functional characterization of circulating cytotoxic T lymphocytes and natural killer cells using the BD FACSymphony™ A1 Cell Analyzer

Autor: Gisele Vanessa Baracho, Nihan Kara, Stephanie Rigaud, Stephanie Widmann, Aaron Tyznik

Publikováno v: The Journal of Immunology. 206:27.14-27.14

Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells have become attractive therapeutic targets for cancer immunotherapy because of their efficient mechanisms for killing cancerous cells. Both effector CTLs and mature NK cells are endowed wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5875b5641f6c7f61f1fe918d7c12cf30
https://doi.org/10.4049/jimmunol.206.supp.27.14

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Leveraging the power of high parameter cell sorting and single-cell multi-omics to profile intratumoral immune cells in a model of B cell lymphoma

Autor: Xiaoshan Shi, Gisele Vanessa Baracho, Wai Lin, John Sedy, Chip Lomas, Stephanie Widmann, Aaron J Tyznik

Publikováno v: The Journal of Immunology. 204:243.17-243.17

The pathogenesis and progression of B-cell lymphomas is a dynamic process involving reciprocal interactions between malignant cells and surrounding components in the tumor microenvironment. Neoplastic B cells migrate to lymphoid sites and prompt the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::793da49897518bd36bbf1eb58056c939
https://doi.org/10.4049/jimmunol.204.supp.243.17

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Assessing CD8+ cytotoxic T-cell dysfunction in obesity and its implications in anti-PD-1 blockade therapy

Autor: Gisele Vanessa Baracho, Hye-Wong Song, Ian Taylor, Stefanie Mortimer, Stephanie Widmann, Aaron J Tyznik

Publikováno v: The Journal of Immunology. 204:86.27-86.27

In chronic conditions, notably cancers, CD8+ cytotoxic T cells gradually lose their effector functions due to constant exposure to antigens and consequent upregulation of inhibitory receptors like PD-1. In this regard, PD-1 blockade therapy was shown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ec9c92459e26feea2283d1c11c08791
https://doi.org/10.4049/jimmunol.204.supp.86.27

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Homozygous hereditary C3 deficiency due to a premature stop codon

Autor: Edimara, Da Silva Reis, Gisele Vanessa, Baracho, Adriana, Sousa Lima, Chuck S, Farah, Lourdes, Isaac

Publikováno v: Journal of clinical immunology. 22(6)

C3 deficiency in humans is a rare disorder characterized by severe recurrent infections. We identified the mutations responsible for a complete homozygous C3 deficiency. Sequencing of the proband C3 cDNA (5067 bp) revealed the following alterations:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a09278a96cbfc5c8e42817e0f4f58a98
https://pubmed.ncbi.nlm.nih.gov/12462331

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