Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gisele Capanema, de Oliveira"'
Autor:
Ana Luiza Valle Martins, Filippo Annoni, Filipe Alex da Silva, Lucas Bolais-Ramos, Gisele Capanema de Oliveira, Renata Cunha Ribeiro, Mirella Monique Lana Diniz, Thuanny Granato Fonseca Silva, Beatriz Dias Pinheiro, Natália Abdo Rodrigues, Alana Helen dos Santos Matos, Daisy Motta-Santos, Maria José Campagnole-Santos, Thiago Verano-Braga, Fabio Silvio Taccone, Robson Augusto Souza Santos
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Background The coronavirus-related disease (COVID-19) is mainly characterized by a respiratory involvement. The renin-angiotensin system (RAS) has a relevant role in the pathogenesis of COVID-19, as the virus enters host’s cells via the an
Externí odkaz:
https://doaj.org/article/b8078596865b49f79e07909e31a4adac
Autor:
Ana Luiza Valle Martins, Filipe Alex da Silva, Lucas Bolais-Ramos, Gisele Capanema de Oliveira, Renata Cunha Ribeiro, Danilo Augusto Alves Pereira, Filippo Annoni, Mirella Monique Lana Diniz, Thuanny Granato Fonseca Silva, Bruna Zivianni, Alexandre Carvalho Cardoso, Juliana Carvalho Martins, Daisy Motta-Santos, Maria José Campagnole-Santos, Fabio Silvio Taccone, Thiago Verano-Braga, Robson Augusto Souza Santos
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Externí odkaz:
https://doaj.org/article/ecec51aaf4c4404186892277ac6bf0ca
Autor:
Ana Luiza Valle Martins, Filippo Annoni, Filipe Alex da Silva, Lucas Bolais-Ramos, Gisele Capanema de Oliveira, Alana Helen dos Santos Matos, Maria Cecília Jardim Heyden, Beatriz Dias Pinheiro, Natália Abdo Rodrigues, Danilo Augusto Alves Pereira, Mirella Monique Lana Diniz, Thuanny Granato Fonseca Silva, Alexandre Carvalho Cardoso, Juliana Carvalho Martins, Daisy Motta-Santos, Maria José Campagnole-Santos, Thiago Verano-Braga, Fabio Silvio Taccone, Robson Augusto Souza dos Santos
BackgroundThe coronavirus-related disease (COVID-19) is mainly characterized by a respiratory involvement, with few available therapeutics for critically cases. The renin-angiotensin system (RAS) has a relevant role in the pathogenesis of COVID-19, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b064ba483cffc2d1c9aebc63e49679ff
https://doi.org/10.1101/2022.09.15.22279897
https://doi.org/10.1101/2022.09.15.22279897
Autor:
Sayonarah C. Rocha, Luis Eduardo M. Quintas, Natasha Paixão, Vanessa Faria Cortes, Gisele Capanema de Oliveira, Silmara L.G. Alves, José A.F.P. Villar, Leandro A. Barbosa, Marco Túlio C. Pessôa, François Noël, Miliane Alves da Silva Lopes
Publikováno v:
The Journal of Membrane Biology. 254:487-497
Na,K-ATPase (NKA) and cardiotonic steroids (CTS) have shown potent cytotoxic and anticancer effects. Here, we have synthesized a series of CTS digoxin derivatives (γ-benzylidene) with substitutions in the lactone ring and evaluated the cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d34b398e1add1bdba8f9b34ba9505255
https://doi.org/10.1007/s00232-021-00186-x
https://doi.org/10.1007/s00232-021-00186-x
Autor:
Bruna Zivianni, Gisele Capanema de Oliveira, Filipe Alex da Silva, Thiago Verano-Braga, Lucas Bolais-Ramos, Alexandre Carvalho Cardoso, Maria José Campagnole-Santos, Renata da Cunha Ribeiro, Danilo Augusto Alves Pereira, Robson A.S. Santos, Filippo Annoni, Ana Luiza Valle Martins, Fabio Silvio Taccone, Daisy Motta-Santos, Juliana Carvalho Martins, Mirella Monique Lana Diniz, Thuanny Granato Fonseca Silva
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research
article-version (VoR) Version of Record
The monocarboxypeptidase angiotensin-converting enzyme 2 (ACE2) is a major player in the the renin–angiotensin system (RAS) as it converts the decapeptide angiotensin (Ang) I to Ang-(1–9) and Ang II to Ang-(1–7) (figure 1a) [1]. ACE2 is also a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db981f062434e0ce4bfc10848089176
https://doi.org/10.1183/23120541.00114-2021
https://doi.org/10.1183/23120541.00114-2021
Autor:
Gisele Capanema, de Oliveira, Sayonarah Carvalho, Rocha, Miliane Alves, da Silva Lopes, Natasha, Paixão, Silmara Lúcia Grego, Alves, Marco Túlio Corrêa, Pessoa, François, Noël, Luis Eduardo M, Quintas, Leandro Augusto, Barbosa, José Augusto Ferreira Perez, Villar, Vanessa Faria, Cortes
Publikováno v:
The Journal of membrane biology. 254(5-6)
Na,K-ATPase (NKA) and cardiotonic steroids (CTS) have shown potent cytotoxic and anticancer effects. Here, we have synthesized a series of CTS digoxin derivatives (γ-benzylidene) with substitutions in the lactone ring and evaluated the cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec8cf09c4a9413a8de6e596f179061a8
https://pubmed.ncbi.nlm.nih.gov/34128090
https://pubmed.ncbi.nlm.nih.gov/34128090
Autor:
Israel José Pereira Garcia, Bruno Antonio Marinho Sanchez, Leandro A. Barbosa, Gisele Capanema de Oliveira, Mariana Helena Chaves, Domingos de Jesus Rodrigues, Fernando de Pilla Varotti, Evaldo dos Santos Monção Filho, Silmara Nunes Andrade, Jessica M M Valadares, Felipe Finger Banfi, Hérica de Lima Santos, Túlio Resende Freitas, Gerardo Magela Vieira Júnior
Publikováno v:
Steroids. 152:108490
Bufadienolide compounds have been used for growth inhibition and apoptosis induction in tumor cells. Those families of cardiotonic steroids can bind the Na,K-ATPase, causing its inhibition. The use of bufadienolides is widely described in the literat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b613e805e3f8edcb7e329d896f9c4b
https://doi.org/10.1016/j.steroids.2019.108490
https://doi.org/10.1016/j.steroids.2019.108490
Autor:
Kahlil Schwanka Salomé, Gisele Capanema de Oliveira, Alex Gutterres Taranto, Moacyr Comar, Natasha Paixão, Leandro A. Barbosa, Luiza D.R. Neves, François Noël, Fernando de Pilla Varotti, Soraya M.F. Oliveira, Fábio Vieira dos Santos, Andersson Barison, Felipe Rocha da Silva Santos, Letícia Gonçalves Resende Ferreira, Gisele Cenzi, Luis Eduardo M. Quintas, Vanessa Faria Cortes, Luciana Madeira da Silva, Silmara L.G. Alves, José A.F.P. Villar
Publikováno v:
Bioorganicmedicinal chemistry. 23(15)
Cardiotonic steroids (CS), natural compounds with traditional use in cardiology, have been recently suggested to exert potent anticancer effects. However, the repertoire of molecules with Na,K-ATPase activity and anticancer properties is limited. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7c2381d397bb7b43f5189d16ed02b1
https://pubmed.ncbi.nlm.nih.gov/26122772
https://pubmed.ncbi.nlm.nih.gov/26122772
Autor:
Leonardo Marmo Moreira, Leandro A. Barbosa, Vanessa Faria Cortes, Grazielle Aparecida Silva Maia, Gisele Capanema de Oliveira, Hérica de Lima Santos
Publikováno v:
Annals of hematology. 92(7)
The aim of the present work was to evaluate the redox and oligomeric effects associated with the human hemoglobin of stored red blood cells that had been previously submitted to gamma radiation. Whole blood was collected from healthy donors and irrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ab3bd5618339dff14e79b3f36d22e4
https://pubmed.ncbi.nlm.nih.gov/23494204
https://pubmed.ncbi.nlm.nih.gov/23494204
Autor:
Gisele Capanema de Oliveira, José A.F.P. Villar, Letícia Gonçalves Resende Ferreira, Luiza D.R. Neves, Leandro A. Barbosa, Silmara L.G. Alves
Publikováno v:
BBR - Biochemistry and Biotechnology Reports. 2:136
Glicosideos cardiacos como a digoxina e digitoxina em doses terapeuticas possuem um efeito inibitorio da Na + /K + -ATPase. Novos compostos sintetizados a partir da digoxina ainda nao possuem nenhuma caracterizacao biologica de efeitos na Na + /K + -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8df193d25355f4e94077224ad97744cd
https://doi.org/10.5433/2316-5200.2013v2n2espp136
https://doi.org/10.5433/2316-5200.2013v2n2espp136