Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Gisela Wohlleben"'
Autor:
Bülent Polat, Gisela Wohlleben, Rebekka Kosmala, Dominik Lisowski, Frederick Mantel, Victor Lewitzki, Mario Löhr, Robert Blum, Petra Herud, Michael Flentje, Camelia-Maria Monoranu
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Despite of a multimodal approach, recurrences can hardly be prevented in glioblastoma. This may be in part due to so called glioma stem cells. However, there is no established marker to identify these stem cells. Methods Paired sa
Externí odkaz:
https://doaj.org/article/396c37a94c354d918bce3f486945a8f5
Autor:
Michael Flentje, Mario Löhr, Rebekka Kosmala, Dominik Lisowski, Robert Blum, V. Lewitzki, Camelia-Maria Monoranu, Bülent Polat, Petra Herud, Gisela Wohlleben, Frederick Mantel
Publikováno v:
Cancer Cell International. 22
Background Despite of a multimodal approach, recurrences can hardly be prevented in glioblastoma. This may be in part due to so called glioma stem cells. However, there is no established marker to identify these stem cells. Methods Paired samples fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4f2f6643fef9720de3e8d02b39f356
https://doi.org/10.1186/s12935-022-02510-4
https://doi.org/10.1186/s12935-022-02510-4
Autor:
Britta Wachter, Patrick Lüningschrör, Camelia M. Monoranu, Jochen Kuper, Elena Bady, Dennis Segebarth, Gisela Wohlleben, Bülent Polat, Rohini Gupta, Robert Blum, Melanie Bauer, Vanessa Luzak, Carmen Villmann, Steven Havlicek, Vanessa Wegat, Georg Langlhofer
Trk receptors and gene fusions of NTRK are targets in precision oncology. Classical Trk signalling concepts fail to explain ligand-independent signalling of intracellular TrkB or NTRK fusion proteins. Here, we show that abundance of the intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::409f5e480533197bebb221e91ef20742
https://doi.org/10.1101/2020.09.11.292565
https://doi.org/10.1101/2020.09.11.292565
Autor:
Till Jasper, Meyer, Agmal, Scherzad, Helena, Moratin, Thomas Eckert, Gehrke, Julian, Killisperger, Rudolf, Hagen, Gisela, Wohlleben, Bülent, Polat, Sofia, Dembski, Norbert, Kleinsasser, Stephan, Hackenberg
Publikováno v:
Materials
Radioresistance is an important cause of head and neck cancer therapy failure. Zinc oxide nanoparticles (ZnO-NP) mediate tumor-selective toxic effects. The aim of this study was to evaluate the potential for radiosensitization of ZnO-NP. The dose-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e524b16ed791fafe02336b8e25c581ce
https://pubmed.ncbi.nlm.nih.gov/31817448
https://pubmed.ncbi.nlm.nih.gov/31817448
Autor:
Stefan Hartmann, Urs D.A. Müller‑Richter, Gisela Wohlleben, Bülent Polat, Axel Seher, Alexander C. Kübler, T Meyer, Muna Brisam
Publikováno v:
Molecular and Clinical Oncology.
Radiotherapy alone, or as an addition to surgery is important for the treatment of head and neck squamous cell carcinoma (HNSCC). In addition to their expression in germ cells, melanoma associated antigens-A (MAGE-A) are only expressed in malignant t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ab88924549c608f22d38b0234862ee
https://doi.org/10.3892/mco.2018.1558
https://doi.org/10.3892/mco.2018.1558
Autor:
Tanja Grimmig, Gisela Wohlleben, Ana Maria Waaga-Gasser, Bülent Polat, Michael Flentje, Martin Gasser, Konstantin Hauff
Publikováno v:
Oncology Reports.
The plasma protein osteopontin (OPN) is considered to be a tumor biomarker, where elevated plasma levels are associated with poor prognosis. Additionally, OPN is expressed in the presence of tumor hypoxia, which is an adverse prognostic factor in rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915487bd3dfc7177a5dcb24377294b2f
https://doi.org/10.3892/or.2017.6068
https://doi.org/10.3892/or.2017.6068
Autor:
Agmal Scherzad, Norbert Kleinsasser, Gisela Wohlleben, Thomas Gehrke, Stephan Hackenberg, B�lent Polat, Rudolf Hagen
Publikováno v:
Oncology reports. 39(4)
The antibiotic drug salinomycin has been reported to mediate cancer cell-specific cytotoxicity, especially regarding cancer stem cells. Since salinomycin has also been reported to arrest cancer cells in the G2 phase, it may have possible radiosensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a70a12c5c653401ed779bc39011c5d6
https://pubmed.ncbi.nlm.nih.gov/29436675
https://pubmed.ncbi.nlm.nih.gov/29436675
Autor:
A. Technau, Cholpon S. Djuzenova, Michael Flentje, Gisela Wohlleben, Buelent Polat, Astrid Katzer
Publikováno v:
Strahlentherapie und Onkologie. 189:62-67
Osteopontin (OPN) is a multifunctional protein overexpressed in many cancers and is involved in tumor progression and metastasis. In lung cancer, elevated OPN expression is associated with an unfavorable prognosis. Therefore, inhibition of OPN is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbe929537d82cd9f5cd6fcb9f84f31f
https://doi.org/10.1007/s00066-012-0238-5
https://doi.org/10.1007/s00066-012-0238-5
Autor:
Tobias Polte, Gesine Hansen, Claudia M. Trujillo-Vargas, Gisela Wohlleben, Tobias A. Oelschlaeger, Klaus J. Erb, Matthias J. Duechs, Thomas Bickert
Publikováno v:
International Archives of Allergy and Immunology. 149:219-230
Background: Recent clinical trials, epidemiological studies and animal experiments have suggested that probiotics may help suppress the development of allergic responses. Objective: To investigate whether the application of the probiotic Escherichia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff31f21eed605b7a0357d039a872f40a
https://doi.org/10.1159/000199717
https://doi.org/10.1159/000199717
Autor:
Gisela, Wohlleben, Agmal, Scherzad, Antje, Güttler, Dirk, Vordermark, Sebastian, Kuger, Michael, Flentje, Buelent, Polat
Publikováno v:
Radiation Oncology (London, England)
Background Tumor hypoxia is a known risk factor for reduced response to radiotherapy. The evaluation of noninvasive methods for the detection of hypoxia is therefore of interest. Osteopontin (OPN) has been discussed as an endogenous hypoxia biomarker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b303cde264d14eac7b60af194db89052
https://pubmed.ncbi.nlm.nih.gov/26259597
https://pubmed.ncbi.nlm.nih.gov/26259597