Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Gisela Sparmann"'
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 6, Pp 1487-1493 (2013)
SUMMARY We have established an extracorporeal bowel model system for the analysis of early events in inflammatory bowel disease (IBD) and therapeutic applications. This model consists of an intestinal segment that is cannulated and perfused in situ,
Externí odkaz:
https://doaj.org/article/d3cf6e59919f4fceb36434ad50e1745a
Autor:
Claus-Peter Schnorr, Hermann Walter, Volker Claus, Wolffried Stucky, Hans-Peter Blatt, Otto Spaniol, Gerd Kaufholz, Rainer Kemp, Wolfgang Paul, Eberhard Bertsch, Herbert Kopp, Manfred Stadel, Ulrich Schmitt, Wolfgang Weidner, Wolfgang Gräber, Dung Huynh, Rockford Ross, Michael Breder, Klaus Estenfeld, Axel Pink, Jan Messerschmidt, Hans Simon, Bernd Becker, Rolf Strothmann, Peter Auler, Johannes Arz, Paul Molitor, Reiner Kolla, Thomas Kretschmer, Franz Josef Schmitt, Ursula Becker, Reiner Marzinkewitsch, Hans Georg Osthof, Uwe Sparmann, Jürgen Sellen, Joachim Hartmann, Yonggang Guan, Gisela Sparmann, Hongzhong Wu, Elmar Schömer, Thomas Burch, Björn Schieffer, Christoph Scholl, Frank Follert, Thomas Chadzelek, Frank Schulz, Jens Eckstein, Matthias Buck, Bin Zhu, Alexander Gamkrelidze, Jörg Sauer, Timo von Oertzen, Tobias Gärtner, Christopher Durst
Publikováno v:
Festschrift zum 90. Geburtstag von Prof. Dr. Dr. h.c. mult. Günter Hotz ISBN: 9783658378219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32e48b6842861657b3f0a0df274a2dcd
https://doi.org/10.1007/978-3-658-37822-6_1
https://doi.org/10.1007/978-3-658-37822-6_1
Publikováno v:
Therapeutic Apheresis and Dialysis. 17:339-347
The aim of this study was to evaluate the safety, tolerability, technical performance and clinical efficacy of a novel adsorptive-type cytapheresis module in patients with active ulcerative colitis. Ten patients with ulcerative colitis (clinical acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0859a0271aeef1fd8d7676a4176904fc
https://doi.org/10.1111/1744-9987.12007
https://doi.org/10.1111/1744-9987.12007
Autor:
Jörg Emmrich, Gisela Sparmann, Marie-Luise Kruse, Nicole Hofmeister-Mielke, D. Wolff, Stefan Liebe, Robert Jaster, Dirk Koczan
Publikováno v:
Cell Research. 20:288-298
Origin and fate of pancreatic stellate cells (PSCs) before, during and after pancreatic injury are a matter of debate. The crucial role of PSCs in the pathogenesis of pancreatic fibrosis is generally accepted. However, the turnover of the cells remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e86fa4fcba20224cad73d5c41f8b0b
https://doi.org/10.1038/cr.2010.10
https://doi.org/10.1038/cr.2010.10
Autor:
Jörg Emmrich, Gisela Sparmann, Anna Karger, Brit Fitzner, Robert Jaster, Stefan Liebe, Peter Brock
Publikováno v:
Cellular Signalling. 20:1865-1872
Pancreatic fibrosis, a key feature of chronic pancreatitis and pancreatic cancer, is mediated by activated pancreatic stellate cells (PSC). Connective tissue growth factor (CTGF) has been suggested to play a major role in fibrogenesis by enhancing PS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31cb9849736b4f141b1ebf38656951dd
https://doi.org/10.1016/j.cellsig.2008.06.016
https://doi.org/10.1016/j.cellsig.2008.06.016
Autor:
Horst Nizze, Stephanie-Anna Holzhüter, Brit Fitzner, Peter Brock, Gisela Sparmann, Jörg Emmrich, Robert Jaster, Stefan Liebe
Publikováno v:
Digestive Diseases and Sciences. 54:309-320
Pancreatic stellate cells (PSC) play a key role in pancreatic fibrosis. Activation of PSC occurs in response to pro-fibrogenic stimuli and is maintained by autocrine loops of mediators, such as endothelin (ET)-1. Here, we have evaluated effects of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee023d764786d3ba9ce5b5334d23ff2
https://doi.org/10.1007/s10620-008-0366-z
https://doi.org/10.1007/s10620-008-0366-z
Publikováno v:
Biochemical Pharmacology. 74:1747-1757
Pancreatic stellate cells (PSCs) are essentially involved in pancreatic fibrogenesis and considered as a target for antifibrotic therapies. Here, we have analyzed the effects of three histone deacetylase inhibitors (HDACIs), sodium butyrate, sodium v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd30c746957da9a94272dabe639915a8
https://doi.org/10.1016/j.bcp.2007.08.023
https://doi.org/10.1016/j.bcp.2007.08.023
Autor:
Dirk Koczan, Änne Glass, Stefan Liebe, Jörg Emmrich, Brit Fitzner, Hana Nechutova, Hans-Jürgen Thiesen, Gisela Sparmann, Thomas Karopka, Robert Jaster, Peter Brock
Publikováno v:
Cellular Signalling. 19:782-790
Pancreatic stellate cells (PSCs) are the main source of extracellular matrix proteins in pancreatic fibrosis, a pathological feature of chronic pancreatitis and pancreatic cancer. Interferon-gamma (IFN-gamma) is an antifibrotic cytokine, but how prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9db9025b361322ca6b69492635522f
https://doi.org/10.1016/j.cellsig.2006.10.002
https://doi.org/10.1016/j.cellsig.2006.10.002
Publikováno v:
Cellular Signalling. 17:1240-1247
Pancreatic stellate cells (PSCs) play a key role in the development of pancreatic fibrosis, a pathological feature of chronic pancreatitis and pancreatic cancer. Here, we show that activation of rat PSCs in vitro is associated with increased expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fead55500fb7968edce0895f6a8cc75
https://doi.org/10.1016/j.cellsig.2004.12.012
https://doi.org/10.1016/j.cellsig.2004.12.012
Autor:
Brit Fitzner, Robert Jaster, Peter Brock, Jörg Emmrich, Stefan Liebe, Gisela Sparmann, Inken Hilgendorf
Publikováno v:
Biochemical Pharmacology. 66:633-641
Pancreatic stellate cells (PSCs) are essentially involved in the development of pancreatic fibrosis, a constant feature of chronic pancreatitis and pancreatic cancer. Profibrogenic mediators, such as ethanol metabolites and cytokines, induce a PSC ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce94c24bca71c7f825f663f3f42d9b81
https://doi.org/10.1016/s0006-2952(03)00390-3
https://doi.org/10.1016/s0006-2952(03)00390-3