Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gisela Papsdorf"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1667:222-228
The influence of the peptide-to-cell ratio and energy depletion on uptake and degradation of the cell-penetrating peptides (CPPs) MAP (model amphipathic peptide) was investigated. The intracellular concentration of the CPPs, MAP and penetratin was mo
Autor:
Matthias F. Melzig, Josef Zipper, Loose R, E Krause, Michael Beyermann, A. Winkler, Gisela Papsdorf
Publikováno v:
Regulatory Peptides. 74:35-40
hCRF inhibits proliferation of corticotropic tumor cells cultivated in serum-reduced medium via interaction with CRF-receptors. This effect was attenuated by the specific antagonist hCRF (9-41), but not by a variety of substances which are inhibitors
Autor:
Maolian Gong, Xiaoou Sun, Jenny Eichhorst, Brit Rentzsch, Kristin Pankow, Björn Maul, Gisela Papsdorf, Wolf-Eberhard Siems, Michael Bader
Publikováno v:
Biological chemistry. 391(2-3)
Membrane-bound human angiotensin-converting enzyme (ACE) has been reported to initiate intracellular signaling after interaction with substrates or inhibitors. Somatic ACE is known to contain two distinct, extracellular catalytic centers. We analyzed
Autor:
Po Wang, Wolf-Eberhard Siems, Xiaoou Sun, Björn Maul, Gisela Papsdorf, Kristin Pankow, Dorothea Lorenz, Nils Dietrich, Burkhard Wiesner
Publikováno v:
Biological chemistry. 389(12)
Angiotensin-converting enzyme (ACE) demonstrates, besides its typical dipeptidyl-carboxypeptidase activity, several unusual functions. Here, we demonstrate with molecular, biochemical, and cellular techniques that the somatic wild-type murine ACE (mA
Autor:
Jens Furkert, Alexander Oksche, Jana Jürgensen, Walter Rosenthal, Gisela Papsdorf, Michael Schaefer, Michael Beyermann, Bernd Gregan
Publikováno v:
The Journal of biological chemistry. 279(26)
Endothelin-1 (ET-1) is a potent vasoactive peptide that acts on endothelin A (ET(A)) and endothelin B (ET(B)) receptors. Although both receptor subtypes are co-expressed in numerous cells, little is known about their ability to form heterodimers. Her
Autor:
H. Peter Reusch, Walter Rosenthal, Jens Furkert, Alexander Oksche, Gisela Papsdorf, Hans-Willi Krell, Ralf Schülein, Michael Beyermann, Evelina Grantcharova
Publikováno v:
The Journal of biological chemistry. 277(46)
The extracellular N terminus of the endothelin B (ET(B)) receptor is susceptible to limited proteolysis (cleavage at R64 downward arrow S65), but the regulation and the functional consequences of the proteolysis remain elusive. We analyzed the ET(B)
Autor:
Walter Rosenthal, Jens Furkert, Gisela Papsdorf, Gregor Boese, Michael Beyermann, Alexander Oksche, Michael Bienert, Angelika Horstmeyer
Publikováno v:
Journal of cardiovascular pharmacology. 36(5 Suppl 1)
We generated fusion proteins consisting of the endothelin-B (ET(B))-receptor and the enhanced green fluorescent protein (EGFP) to visualize receptor internalization. In Madin Darby canine kidney (MDCK) clones expressing ET(B)/EGFP fusion proteins, si
Autor:
Matthias F. Melzig, Wolf-Eberhard Siems, Gisela Papsdorf, Jörns Fickel, Jutta Odarjuk, A. Winkler
Publikováno v:
European journal of pharmacology. 291(1)
Although substance P is known to take part in the regulation of the anterior pituitary, no conclusive evidence for the expression of the tachykinin NK1 receptor has been found yet in the pituitary or pituitary derived cells. With the reverse transcri
Publikováno v:
Regulatory Peptides. 53:S117-S118
SP is one of the three distinct peptides of the tachykinin system. These peptides possess a common spectrum of biological activities including a sensory transmission in the nervous system and contraction/ relaxation of peripheral smooth muscle. We we