Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

Autor: Bernadette Carroll, Dorothea Maetzel, Oliver DK Maddocks, Gisela Otten, Matthew Ratcliff, Graham R Smith, Elaine A Dunlop, João F Passos, Owen R Davies, Rudolf Jaenisch, Andrew R Tee, Sovan Sarkar, Viktor I Korolchuk

Publikováno v: eLife, Vol 5 (2016)

The mammalian target of rapamycin complex 1 (mTORC1) is the key signaling hub that regulates cellular protein homeostasis, growth, and proliferation in health and disease. As a prerequisite for activation of mTORC1 by hormones and mitogens, there fir

Externí odkaz: https://doaj.org/article/6984fb5071a4478b8cce115a8801a2ad

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

Autor: Gisela Otten, João F. Passos, Dorothea Maetzel, Owen R. Davies, Elaine A. Dunlop, Graham Smith, Bernadette Carroll, Sovan Sarkar, Rudolf Jaenisch, Matthew Ratcliff, Oliver D. K. Maddocks, Andrew R. Tee, Viktor I. Korolchuk

Publikováno v: Carroll, B, Maetzel, D, Maddocks, O D, Otten, G, Ratcliff, M, Smith, G R, Dunlop, E A, Passos, J F, Davies, O R, Jaenisch, R, Tee, A R, Sarkar, S & Korolchuk, V I 2016, ' Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity ', eLIFE, vol. 5, e11058 . https://doi.org/10.7554/eLife.11058
eLife Sciences Publications, Ltd.
Carroll, B, Maetzel, D, Maddocks, O D K, Otten, G, Ratcliff, M, Smith, G R, Dunlop, E A, Passos, J F, Davies, O R, Jaenisch, R, R.Tee, A, Sarkar, S & Korolchuk, V I 2016, ' Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity ', eLife, vol. 5, no. JAN, e11058 . https://doi.org/10.7554/eLife.11058, https://doi.org/10.7554/eLife.11058.001
eLife, Vol 5 (2016)
eLife

The mammalian target of rapamycin complex 1 (mTORC1) is the key signaling hub that regulates cellular protein homeostasis, growth, and proliferation in health and disease. As a prerequisite for activation of mTORC1 by hormones and mitogens, there fir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab7b19fe3592bded37752ffcc9a4d6e
https://www.pure.ed.ac.uk/ws/files/206782183/elife_11058_v3.pdf