Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gisela Moehren"'
Autor:
Igor Goryanin, Gisela Moehren, Jan B. Hoek, N I Markevich, Anatoly Kiyatkin, Boris N. Kholodenko, Oleg Demin
Publikováno v:
Biochemistry. 41:306-320
Stimulation of isolated hepatocytes with epidermal growth factor (EGF) causes rapid tyrosine phosphorylation of the EGF receptor (EGFR) and adapter/target proteins, which was monitored with 1 and 2 s resolution at 37, 20, and 4 degrees C. The tempora
Autor:
Michael Bertovich, Gisela Moehren, Frank H. Michaels, Hilary Koprowski, John L. Farber, Sergei Spitsin
Publikováno v:
Molecular Medicine. 3:315-326
The production of nitric oxide by type II inducible nitric oxide synthase (type II NOS) gene is controlled at least in part by transcriptional activation. Although the murine and human type II NOS genes share significant sequence homology, they diffe
Autor:
Katsuhisa Saso, Makoto Hoshino, Jan B. Hoek, Makoto Ito, Katsuyoshi Higashi, Tomoyuki Nomura, Gisela Moehren
Publikováno v:
Alcoholism: Clinical and Experimental Research. 20:330A-334A
Hepatocyte growth factor (HGF) is the most potent mitogen identified for hepatocytes and is thought to be an important growth factor in the regulation of liver regeneration. Its effects are mediated through a tyrosine kinase receptor, the product of
Autor:
Christine Benistant, Gisela Moehren, Jan B. Hoek, Raphael Rubin, Eugenia Torres-Marquez, Lena Gustavsson
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1223:84-90
The relationship between phospholipase D and C activation was studied in intact rat hepatocytes and rat liver plasma membranes. In intact hepatocytes, in the presence of ethanol, vasopressin, phorbol ester, and calcium independently stimulated phosph
Autor:
M E Torres-Marquez, Jan B. Hoek, Lena Gustavsson, Gisela Moehren, Christine Benistant, Raphael Rubin
Publikováno v:
Scopus-Elsevier
Ca(2+)-dependent and protein kinase C-dependent mechanisms of phospholipase D (PLD) activation were studied in rat hepatocytes by measuring phosphatidylethanol (Peth) formation in the presence of ethanol. Stimulation of Peth formation by 12-O-tetrade
Publikováno v:
Scopus-Elsevier
Activation of phospholipase D (PLD) by receptor-coupled stimuli (vasopressin, ATP), phorbol esters, and Ca2+ ionophores was studied in isolated rat hepatocytes, double labeled with [3H]arachidonate and [14C]stearate. Phosphatidylethanol (Peth) was fo
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1177:87-92
The activation of phospholipase D in the kidney could be detected in vivo in rats treated with ethanol by the accumulation of phosphatidylethanol. Unilateral nephrectomy stimulated the activity of phospholipase D in the remaining kidney as indicated
Publikováno v:
Scopus-Elsevier
The effect of Ca2+ on the rate of pyruvate carboxylation was studied in liver mitochondria from control and glucagon-treated rats, prepared under conditions that maintain low Ca2+ levels (1-3 nmol/mg of protein). When the matrix-free [Ca2+] was low (
Autor:
N I Markevich, Boris N. Kholodenko, Gisela Moehren, Oleg Demin, Anatoly Kiyatkin, Jan B. Hoek
Publikováno v:
Systems biology. 1(1)
A systems biology approach is applied to gain a quantitative understanding of the integration of signalling by the small GTPase Ras. The Ras protein acts as a critical switch in response to signals that determine the cell's fate. In unstimulated cell
Autor:
Gisela Moehren, Nathan Janes, Theodore F. Taraschi, Jan B. Hoek, Emanuel Rubin, Alexander V. Victorov
Publikováno v:
Journal of the American Chemical Society. 116:4050-4052