Výsledky vyhledávání - "Gisela Betzl"

Epigenetic Modification of Transgenes under the Control of the Mouse Mammary Tumor Virus LTR: Tissue-Dependent Influence on Transcription of the Transgenes

Autor: Ulrich H. Weidle, Gottfried Brem, Gisela Betzl

Publikováno v: Biological Chemistry Hoppe-Seyler. 377:711-720

Transgenic mice expressing human urokinase, as well as animals expressing human urokinase receptor under the control of the murine mammary tumor virus (MMTV) long terminal repeat, were established. In the vast majority of the founder animals and thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d040db1ad72d78f2dc67c14db1200e
https://doi.org/10.1515/bchm3.1996.377.11.711

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Gene expression analysis in biomarker research and early drug development using function tested reverse transcription quantitative real-time PCR assays

Autor: Sabine Lohmann, Kathy Schostack, Xuefeng Yin, Leopoldo Luistro, Hua Zhong, Manuela Poignée-Heger, Mark DeMario, Anton Belousov, Andrea Herold, Gisela Betzl, Mary Simcox, Heiko Walch, Tobias Bergauer, Martin Weisser, Manuel Dietrich

Publikováno v: Methods (San Diego, Calif.). 59(1)

The identification of new biomarkers is essential in the implementation of personalized health care strategies that offer new therapeutic approaches with optimized and individualized treatment. In support of hypothesis generation and testing in the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f265074f91737a5ca2e39cf765ab8aa
https://pubmed.ncbi.nlm.nih.gov/22796720

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A general method for chimerization of monoclonal antibodies by inverse polymerase chain reaction which conserves authentic N-terminal sequences

Autor: Gisela Betzl, Brigitte Kaluza, Tibor Diamantstein, Ulrich H. Weidle, Hui Shao

Publikováno v: Gene. 122:321-328

Chimerization of antibodies (Ab) by cloning the V (variable) regions encoding the light and heavy chains with degenerate oligodeoxyribonucleotide primers matching to framework region 1 and to the joining regions, leads to Ab with altered amino acids

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1311d044f01d2dbcdc49c7bc94dd67
https://doi.org/10.1016/0378-1119(92)90221-a

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Massive parallel bisulfite sequencing of CG-rich DNA fragments reveals that methylation of many X-chromosomal CpG islands in female blood DNA is incomplete

Autor: Karin Buiting, Gisela Betzl, Epameinondas Fritzilas, Stephanie Gross, Bernhard Horsthemke, Caroline Sirsch, Michael Zeschnigk, Sven Rahmann, Marcel Martin, Andreas Kalbe, Bruno Frey

Methylation of CpG islands (CGIs) plays an important role in gene silencing. For genome-wide methylation analysis of CGIs in female white blood cells and in sperm, we used four restriction enzymes and a size selection step to prepare DNA libraries en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e182dbe0033985d4abf4fdcef0ed50b0
https://doi.org/10.1093/hmg/ddp054

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