Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gisela Anabel Samaja"'
Autor:
Niek Bastiaensen, Gisela Anabel Samaja, Gerardo Burton, Darío A. Estrin, Daniela Navalesi, M. Celeste del Fueyo, Adali Pecci, Diego Y. Grinman, Lautaro D. Alvarez, René Houtman, Adriana S. Veleiro, M. Virginia Dansey
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1851:1577-1586
Background: Liver X receptors (LXRs) are transcription factors activated by cholesterol metabolites containing an oxidized side chain. Due to their ability to regulate lipid metabolism and cholesterol transport, they have become attractive pharmacolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ef0a48ba5f0fa62b0061526cbb1889
https://doi.org/10.1016/j.bbalip.2015.09.007
https://doi.org/10.1016/j.bbalip.2015.09.007
Autor:
Adali Pecci, Lautaro D. Alvarez, Gerardo Burton, Maria Virginia Dansey, Gisela Anabel Samaja, Adriana S. Veleiro, Olga A. Castro, Daiana S. Escudero
Publikováno v:
The Biochemical journal. 465(1)
Dafachronic acids (DAs) are 3-keto cholestenoic acids bearing a carboxylic acid moiety at the end of the steroid side chain. These compounds interact with the DAF-12 receptor, a ligand-dependent transcription factor that acts as a molecular switch me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abae4c10751e27c2240b551295457477
https://pubmed.ncbi.nlm.nih.gov/25374049
https://pubmed.ncbi.nlm.nih.gov/25374049
Autor:
Gerardo Burton, Gisela Anabel Samaja, Adali Pecci, Olga A. Castro, Adriana S. Veleiro, Lautaro D. Alvarez, Daiana S. Escudero, Maria Virginia Dansey
27-Nor-Δ4-dafachronic acid was prepared in nine steps and 14% overall yield by two sequential 2-carbon homologations from 20β-carboxyaldehyde-4-pregnen-3-one. Its activity was evaluated in vivo, where it rescued the Mig phenotype of daf-9(rh50) Cae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329ca84d7b2235d34091a6706f3e608e
http://www.sciencedirect.com/science/article/pii/S0960894X13003995
http://www.sciencedirect.com/science/article/pii/S0960894X13003995
