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Proper chromosome segregation depends on establishment of bioriented kinetochore-microtubule attachments, which often requires multiple rounds of release and reattachment. Aurora B and C kinases phosphorylate kinetochore proteins to release tensionle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c6af746badf6848a882c329c256d96
https://doi.org/10.1101/2023.02.05.527197
https://doi.org/10.1101/2023.02.05.527197
Publikováno v:
Journal of visualized experiments : JoVE. (188)
Time-lapse fluorescence microscopy has revolutionized the understanding of meiotic cell-cycle events by providing temporal and spatial data that is often not seen by imaging fixed cells. Budding yeast has proved to be an important model organism to s
Publikováno v:
Journal of Visualized Experiments.
Publikováno v:
The Journal of Cell Biology
Cairo et al. show that in S. cerevisiae meiosis, spindle checkpoint proteins Bub1 and Bub3 have a critical role in preventing chromosome missegregation and setting the normal duration of anaphase I and II onset by regulating the kinetochore-localizat
Accurate chromosome segregation depends on proper attachment of kinetochores to spindle microtubules prior to anaphase onset. The Ipl1/Aurora B kinase corrects improper attachments by phosphorylating kinetochore components and so releasing aberrant k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3186871f32dbac21cb76a2210c5743c