Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Gisèle Cherqui"'
Autor:
François Lallemand, Anne Mazars, Céline Prunier, France Bertrand, Michel Kornprost, Sylvie Gallea, Sergio Roman-Roman, Gisèle Cherqui, Azeddine Atfi
Publikováno v:
Oncogene. 20:879-884
In this study, we examined the effect of the stable expression of Smad7 in two different cell lines on apoptosis induced by various stimuli including TGF-beta, serum withdrawal, loss of cell adhesion (anoikis) and TNF-alpha. Smad7 increased TGF-beta-
Autor:
Gisèle Cherqui, Jacqueline Capeau, Christèle Desbois-Mouthon, Martine Caron, O. Lascols, Jocelyne Magré, Corinne Vigouroux
Publikováno v:
Journal de la Société de Biologie. 195:249-257
La resistance a l’insuline est une anomalie metabolique frequente. Elle joue un role important dans le syndrome metabolique (ou syndrome X), le diabete de type 2, l’obesite, les syndromes lipodystrophiques plus recemment individualises survenant
Autor:
Gisèle Cherqui, Hélène Robin, Christèle Desbois-Mouthon, Axelle Cadoret, F. Bertrand, Azzedine Atfi, Céline Prunier, Jacqueline Capeau
Publikováno v:
Journal of Biological Chemistry. 274:30596-30602
We recently showed that the antiapoptotic function of insulin requires nuclear factor kappaB (NF-kappaB) activation (Bertrand, F., Atfi, A., Cadoret, A., L'Allemain, G., Robin, H., Lascols, O., Capeau, J., and Cherqui, G. (1998) J. Biol. Chem. 273, 2
Autor:
Jacqueline Capeau, Christèle Desbois-Mouthon, Corinne Vigouroux, Martine Auclair, Gisèle Cherqui, Martine Caron, O. Lascols, Joëlle Deibener, Pierre Kaminski
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 84:3197-3206
We report here that antiinsulin receptor (anti-IR) autoantibodies (AIRs) from a newly diagnosed patient with type B syndrome of insulin resistance induced cellular resistance not only to insulin but also to insulin-like growth factor I (IGF-I) for th
Autor:
Agnès Bellocq, Sidonie Suberville, Carole Philippe, France Bertrand, Joëlle Perez, Bruno Fouqueray, Gisèle Cherqui, Laurent Baud
Publikováno v:
Journal of Biological Chemistry. 273:5086-5092
Stimulation of macrophages with endotoxin and/or cytokines is responsible for the expression of the inducible isoform of nitric oxide synthase (iNOS). Because macrophages are exposed to low pH within the microenvironment of inflammatory lesions, the
Autor:
Gisèle Cherqui, Susan E. Davenport, Monique. Mergey, Christian Gespach, Richard C. Boucher, Sherif E. Gabriel
Publikováno v:
Biochemical and Biophysical Research Communications. 229:663-672
We evaluated the role of the activated Ras and Src/PyMT ( Polyoma Middle T ) signaling pathways on the expression of the cystic fibrosis transmembrane conductance regulator (CFTR) in human colonic Caco-2 cell lines. Control vector-transfected Caco-2
Autor:
Martine Caron, Corinne Vigouroux, Jocelyne Magré, O. Lascols, Jacqueline Capeau, Christèle Desbois-Mouthon, Gisèle Cherqui
Publikováno v:
Nutrition Clinique et Métabolisme. 10:231-242
Resume Les effets metaboliques majeurs de l'insuline sur le metabolisme glucidique, lipidique et proteique sont connus depuis longtemps. Plus recemment, un role dans la proliferation et la differenciation cellulaire a ete affirme. La connaissance des
Autor:
Gisèle Cherqui, P J Antoine, Carole Philippe, Laurent Baud, Jacqueline Capeau, André Groyer, F. Bertrand
Publikováno v:
Journal of Biological Chemistry. 270:24435-24441
We examined the effect of insulin on nuclear factor kappa B (NF-kappa B) activity in Chinese ovary (CHO) cells overexpressing wild-type (CHO-R cells) or -defective insulin receptors mutated at Tyr1162 and Tyr1163 autophosphorylation sites (CHO-Y2 cel
Autor:
Jacqueline Capeau, S Baron-Delage, Christian Gespach, Véronique Barbu, Eric Chastre, Peggy Levy, Gisèle Cherqui
Publikováno v:
Journal of Biological Chemistry. 269:18686-18693
Taking advantage of the potent mitogenic effect exerted by insulin in human colonic cells, we used Caco-2 cells transfected with an activated (Val-12) human Haras gene or the polyoma middle T (PyMT) oncogene, a constitutive activator of pp60c-src tyr
Publikováno v:
Hepatology. 19:1164-1170
Endogenous bile acids such as chenodeoxycholic acid have been shown to display a suppressive effect in vitro on mononuclear cell activation. We investigated the signal transduction pathway involved in the effect of chenodeoxycholic acid on monocyte p