High-affinity σ1 protein agonist reduces clinical and pathological signs of experimental autoimmune encephalomyelitis

Autor: Oxombre, Bénédicte, Lee Chang, Catalina, Duhamel, Alain, Toussaint, Marion, Giroux, Mariane, Donnier-Maréchal, Marion, Carato, Pascal, Lefranc, Didier, Zéphir, Hélène, Lionel, Prin, Melnyk, Patricia, Vermersch, Patrick

Publikováno v: British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2015, 172 (7), pp.1769-1782. ⟨10.1111/bph.13037⟩
British Journal of Pharmacology, 2015, 172 (7), pp.1769-1782. ⟨10.1111/bph.13037⟩

International audience; BACKGROUND AND PURPOSE Selective agonists of the sigma-1 receptor (σ1 protein) are generally reported to protect against neuronal damage and modulate oligodendrocyte differentiation. Human and rodent lymphocytes possess satur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3716fa2e6dc394170afd005e072a39f6
https://hal.archives-ouvertes.fr/hal-02060823