Non-immunogenic recombinant staphylokinase versus alteplase for patients with acute ischaemic stroke 4·5 h after symptom onset in Russia (FRIDA): a randomised, open label, multicentre, parallel-group, non-inferiority trial

Autor: Gusev, Eugene I, Martynov, Mikhail Yu, Nikonov, Alexey A, Shamalov, Nikolay A, Semenov, Michail P, Gerasimets, Eugene A, Yarovaya, Elena B, Semenov, Andrey M, Archakov, Alexander I, Markin, Sergey S, Aksentiev, Sergey B, Yunevich, Denis S., Alasheev, Andrey M, Androfagina, Olga V, Bobkov, Vladimir V, Choroshavina, Ksenia V, Chefranova, Janna Yu, Lykov, Yuriy A, Chuprina, Svetlana E, Vorobev, Andrey A, Dobrovolskiy, Alexey V, Elemanov, Ulukpan A, Fedaynin, Sergey A, Gorbachev, Vladimir I, Korobeinikov, Ivan V, Greshnova, Irina V, Korsunskaya, Larisa L, Nikonova, Anastasiya A, Kudinov, Vasily A, Artyushev, Rafael I, Kutsenko, Vladimir A, Nesterova, Valentina N, Nizov, Alexey A, Girivenko, Alexey I, Orlovsky, Alexey A, Ponomarev, Eduard A, Popov, Dmitriy V, Pribylov, Sergey A, Semikhin, Alexander S, Timchenko, Ludmila V, Jadan, Olga N, Zakharov, Sergey A, Chirkov, Alexander N, Zhukovskaya, Natalya V

Publikováno v: In The Lancet Neurology September 2021 20(9):721-728

[Nonimmunogenic staphylokinase in the treatment of acute ischemic stroke (FRIDA trial results)].

Autor: Gusev EI; Pirogov Russian National Research Medical University, Moscow, Russia., Martynov MY; Pirogov Russian National Research Medical University, Moscow, Russia.; Federal Center of Brain Research and Neurotechnologies, Moscow, Russia., Shamalov NA; Federal Center of Brain Research and Neurotechnologies, Moscow, Russia., Yarovaya EB; Lomonosov Moscow State University, Moscow, Russia., Semenov MP; Peoples' Friendship University of Russia, Moscow, Russia., Semenov AM; Peoples' Friendship University of Russia, Moscow, Russia.; Supergene, LLC, Moscow, Russia., Orlovsky AA; Lomonosov Moscow State University, Moscow, Russia., Kutsenko VA; Lomonosov Moscow State University, Moscow, Russia., Nikonov AA; Pirogov Russian National Research Medical University, Moscow, Russia., Aksentiev SB; Regional Clinical Hospital, Ryazan, Russia., Yunevich DS; Regional Clinical Hospital, Ryazan, Russia., Alasheev AM; Regional Clinical Hospital No. 1, Yekaterinburg, Russia., Androfagina OV; Regional Clinical Hospital, Samara, Russia., Bobkov VV; Regional Clinical Hospital, Tver, Russia., Choroshavina KV; Regional Clinical Hospital, Tver, Russia., Gorbachev VI; Regional Clinical Hospital, Irkutsk, Russia., Korobeynikov IV; Regional Clinical Hospital, Irkutsk, Russia., Greshnova IV; Regional Clinical Hospital, Ulyanovsk, Russia., Dobrovolskiy AV; EFIS Research Centre, LLC, Moscow, Russia., Elemanov UA; Regional Clinical Hospital, Kaluga, Russia., Zhukovskaya NV; Regional Clinical Hospital of the Leningrad Region, St. Petersburg, Russia., Zakharov SA; Regional Clinical Hospital, Orenburg, Russia., Chirkov AN; Regional Clinical Hospital, Orenburg, Russia., Korsunskaya LL; Simferopol City Clinical Hospital No. 7, Simferopol, Russia., Nesterova VN; Regional Clinical Hospital, Nizhny Novgorod, Russia., Nikonova AA; Pirogov Russian National Research Medical University, Moscow, Russia., Nizov AA; City Clinical Hospital No. 11, Ryazan, Russia., Girivenko AI; City Clinical Hospital No. 11, Ryazan, Russia., Ponomarev EA; City Clinical Hospital of Emergency No. 25, Volgograd, Russia., Popov DV; City Clinical Hospital No. 3, Chelyabinsk, Russia., Pribylov SA; Regional Clinical Hospital, Kursk, Russia., Semikhin AS; MIREA - Russian Technological University, Moscow, Russia., Timchenko LV; Ochapowski Regional Hospital No. 1, Krasnodar, Russia., Jadan ON; Ochapowski Regional Hospital No. 1, Krasnodar, Russia., Fedyanin SA; Regional Clinical Hospital, Barnaul, Russia., Chefranova ZY; St. Iosaf's Belgorod Regional Clinical Hospital, Belgorod, Russia., Lykov YA; St. Iosaf's Belgorod Regional Clinical Hospital, Belgorod, Russia., Chuprina SE; Regional Clinical Hospital No. 1, Voronezh, Russia., Vorobev AA; Regional Clinical Hospital No. 1, Voronezh, Russia., Archakov AI; Orekhovich Institute of Biomedical Chemistry, Moscow, Russia., Markin SS; Orekhovich Institute of Biomedical Chemistry, Moscow, Russia.; Supergene, LLC, Moscow, Russia.

Publikováno v: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2022; Vol. 122 (7), pp. 56-65.