Hair follicle differentiation‐specific keratin expression in human basal cell carcinoma

Autor: A Mukhtar, Carlotta Olivero, Huw Morgan, A. Benketah, Girish Khandubhai Patel, Emma Rees, S. Ziaj, Simone Lanfredini

Publikováno v: Clinical and Experimental Dermatology. 45:417-425

Background Identification of human basal cell carcinoma (BCC) cancer stem cells and cellular hierarchy inherently implies the presence of differentiation. By conventional histological analysis, BCC demonstrates tumour nodules that appear relatively h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7faacb2fd76573c933b27a02ad370ffb
https://doi.org/10.1111/ced.14113

Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic, non-inferiority, randomised controlled trial

Autor: John R. Ingram, H K Bell, Gudula Kirtschig, B Walker, Fiona Antony, M Walsh, Eva-B. Bröcker, Ingrid Salvary, J Wee, Emilia Duarte-Williamson, H Santander, Kathy Taghipour, David Gawkrodger, Enno Schmidt, Sam Gibbs, Alison M Layton, Michael Sticherling, J Adams, M Vatve, Joanne R Chalmers, Hywel C Williams, Fiona Craig, S Blackford, A Carmichael, Walter Bottomley, Adzura Azam, Chris Lovell, Karen E. Harman, Margaret Childs, Alexander Vincent Anstey, K. Hussain, Marinella Nik, C Günthert, A. Chapman, N. van Beek, Andrew M Wright, Rainer Hügel, C Barnard, Indre Verpetinske, K Davies, Thomas A. Luger, A Omerod, Karen Gibbon, Alex Waters, V Akhras, Robert Charles-Holmes, Shyamal Wahie, John C. English, James Mason, R.R. Coelho, Girish Khandubhai Patel, Robert Ellis, Jane C. Sterling, A Lloyd Lavery, Thomas R. Godec, Fenella Wojnarowska, Jane Ravenscroft, Richard Groves, H Malhomme, Kerstin Steinbrink, Andrew J. Nunn, Regine Gläser, Emma Veysey, Adam Ferguson, V Lewis, Diane Whitham, V Venning, M Westmoreland, G Wong, Chris Bower, N. Hepburn, C Thomas, P J Hampton, R. Wachsmuth, Andrew Ilchyshyn, Nick J. Levell, M G S Dunnill, S. Walton, R Rallan

Publikováno v: Lancet (London, England)

BACKGROUND: Bullous pemphigoid is a blistering skin disorder with increased mortality. We tested whether a strategy of starting treatment with doxycycline gives acceptable short-term blister control while conferring long-term safety advantages over s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5e1678ec8864f4fa72ceb86b309227
http://europepmc.org/articles/PMC5400809

β-HPV infection correlates with early stages of carcinogenesis in skin tumors and patient-derived xenografts from a kidney transplant recipient cohort

Autor: Elena Trisolini, Paola Savoia, Girish Khandubhai Patel, Federica Calati, Renzo Boldorini, Cinzia Borgogna, Marco De Andrea, Marisa Gariglio, Simone Lanfredini, Elisa Zavattaro, Carlotta Olivero

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)
Frontiers in Microbiology

Many malignancies that occur in high excess in kidney transplant recipients (KTRs) are due to viruses that thrive in the setting of immunosuppression. Keratinocyte carcinoma (KC), the most frequently occurring cancer type in KTR, has been associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee659b0a99a074b187016b74d5debca

Identification of Human Cutaneous Basal Cell Carcinoma Cancer Stem Cells

Autor: Huw Morgan, Girish Khandubhai Patel, Carlotta Olivero

Publikováno v: Skin Stem Cells ISBN: 9781493988693

The cancer stem cell model states that a subset of tumor cells, called "cancer stem cells," can initiate and propagate tumor growth through self-renewal, high proliferative capacity, and their ability to recreate tumor heterogeneity. In basal cell ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1538e5896e02fe657cc62935bed35c0d
https://doi.org/10.1007/7651_2018_133

Delayed and localized pemphigus vulgaris after breast cancer radiotherapy

Autor: John R. Ingram, Doreen Yin Hui Lee, Natalie M. Stone, Hiu Kwan Carolyn Tang, Ian Thompson, Girish Khandubhai Patel

Breast cancer treatment involving ionizing radiation causes characteristic radiation dermatitis in the majority of patients. The DNA damaging effects of radiation can rarely predispose to primary inflammatory dermatoses, such as pemphigus vulgaris. I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b64a8bdc1c8e9becb1b7a69fc8da724