Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Girish B. Chheda"'
Autor:
Thamarapu Srikrishnan, James L. Alderfer, Aruna V. Arakali, Girish B. Chheda, J. McCloskeyt, R. Parthasarathy
Publikováno v:
Nucleosides and Nucleotides. 16:2193-2218
Creatinine (2-amino-1,5- dihydro-1-methyl-4-imidazolone) is a natural by-product of cellular metabolism related to muscular mass. It is excreted in human urine and is necessary for normal kidney function. Urinary secretion of creatinine serves as a b
Publikováno v:
Nucleosides and Nucleotides. 16:239-255
The modified nucleic acid base, 6-amino-3-methyl-5-(N-formylamino)uracil is one of three new modified uracil derivatives isolated and extracted from human urine in our laboratory. X-ray crystallographic investigation was undertaken to understand the
Publikováno v:
Nucleosides and Nucleotides. 14:1519-1537
A novel modified nucleoside, 1-α-D-Ribofuranosyl-4-pyridone-3-carboxamide, has been isolated from the urines of one normal human individual and two CML patients. The structure was assigned on the basis of UV, NMR and mass spectral data and confirmed
Publikováno v:
ChemInform. 26
A novel modified nucleoside, 1-α-D-Ribofuranosyl-4-pyridone-3-carboxamide, has been isolated from the urines of one normal human individual and two CML patients. The structure was assigned on the basis of UV, NMR and mass spectral data and confirmed
Publikováno v:
Nucleosides and Nucleotides. 9:151-162
N 6 −(1-hydroxyguanidino)purine IIa, and its 9-β-D-ribonucleoside derivative IIb were prepared by reacting at room temperature 6-hydroxyadenine Ia and 6-hydroxyadenosine Ib, with 1-guanyl-3,5-dimethylpyrazole nitrate in DMF. Refluxing IIa and IIb
Publikováno v:
Nucleosidesnucleotides. 18(10)
Two new modified uracil nucleosides, 5-carbamoylmethyuridine (ncm5U, I) and 5-carbamoylmethyl-2-thiouridine (ncm5s2U, II) were isolated from a 24 hr collection of a normal human urine. The structures were assigned on the basis of UV, NMR and mass spe
Publikováno v:
Nucleosides and Nucleotides. 9:441-442
Elevation of 5-carbamoylmethyluridine in the urines of non-small lung carcinoma patients suggests that this nucleoside may be used as an indicator of tumor burden for these patients.
Publikováno v:
Biochemical Pharmacology. 24:83-87
Two purine analogs, 7-deazaadenosine (tubercidin) and isopropylureidopurine (IPUP), have been found to inhibit the uracil tRNA-methylating enzymes of Escherichia coli. Conversion of isopropylureidopurine to its ribonucleoside derivative rendered it i
Autor:
Nimai De, Martin P. Schweizer, Mark J. Brown, Mark W. Pulsipher, P.Rabindra Reddy, Girish B. Chheda, C. R. Petrie
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 802:352-361
Magnesium and manganese ions bind strongly to the unusual transfer RNA anticodon loop nucleotides, N-[(9-β- d - ribofuranosyl -9H- purin -6- yl ) carbamoyl ]- l - threonine 5′-monophosphate (pt 6 A) and uridine-5-oxyacetic acid 5′-monophosphate
Publikováno v:
Biochemistry. 16:4999-5008