Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Girij Pal Singh"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 2680-2715 (2021)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
Sugar-modified nucleosides have gained considerable attention in the scientific community, either for use as molecular probes or as therapeutic agents. When the methylene group of the ribose ring is replaced with a sulfur atom at the 3’-position, t
Autor:
Gautham G. Shenoy, Nandu Baban Bhise, Sachin Arun Sasane, Mofazzal Husain, Alex Joseph, Girij Pal Singh
Publikováno v:
Organic Preparations and Procedures International. 53:1-8
(S)-Duloxetine hydrochloride 1 is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain (Figure 1). 1 , 2 Due to its versatility in d...
Autor:
Dhananjai Srivastava, Harishchandra Sambhaji Jadhav, BS Jayashree, Gautham G. Shenoy, Umesh Parasharam Aher, Girij Pal Singh
Publikováno v:
Organic Process Research & Development. 24:387-397
A stereoselective large-scale synthetic process is described to produce 1,3-oxathiolane nucleoside, lamivudine. A mild, inexpensive, and readily available zirconium (IV) chloride (ZrCl4) catalyst a...
Autor:
Sunil Kumar Vinubhai Gohel, Girij Pal Singh, Vasanthi Palanisamy, Palash Sanphui, Vladimir V. Chernyshev, Muthuramalingam Prakash
Publikováno v:
RSC advances. 11(49)
Muscle relaxant and pain reliever metaxalone (MET) is a biopharmaceutical classification systems (BCS) class II drug with poor aqueous solubility and high permeability. The presence of an aromatic skeleton and cyclic carboxamate moiety are the probab
Autor:
Girij Pal Singh, Varadaraj G Bhat, Anurag Trivedi, Himanshu M. Godbole, Gautham G. Shenoy, Bhushan B. Borase, Pritesh R. Upadhyay
Publikováno v:
Journal of Chemical Sciences. 133
Herein, we have described a novel and concise synthesis of the potent angiotensin-converting enzyme (ACE) inhibitor, benazepril hydrochloride (7) in trifluoroethanol via an Ugi three-component reaction in shorter reaction times. The key step is the t
Publikováno v:
Synthetic Communications. 49:2350-2356
An improved process for the synthesis of latanoprost having excellent optical purity (de 99.9%, [α]D20 = +35.37° (c = 0.90, acetonitrile)) without use of preparative HPLC is described. This...
Autor:
Palash Sanphui, Sunil Kumar Vinubhai Gohel, Girij Pal Singh, Krishnamurthy Bhat, Muthuramalingam Prakash
Publikováno v:
Journal of Molecular Structure. 1178:479-490
Supramolecular reactions between a muscle relaxant drug, Metaxalone, 5-[(3,5-dimethylphenoxy) methyl]-2-oxazolidinone with a few carboxamides like nicotinamide, isonicotinamide, salicylamide and carboxylic acid coformers such as 3- ydroxybenzoic acid
Autor:
Krishnamurthy Bhat, Anurag Trivedi, Pritesh R. Upadhyay, SG Vasantharaju, Sunil R. Murkute, Himanshu M. Godbole, Girij Pal Singh
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 207:114416
Ziprasidone hydrochloride is a second-generation antipsychotic drug employed for the treatment of schizophrenia and acute mania or mixed episodes associated with bipolar disorder. During the scale-up of ziprasidone hydrochloride, an unknown impurity
Autor:
Narotham Venkata Maddireddy, Gautham G. Shenoy, Girij Pal Singh, Himanshu M. Godbole, Suvarna G. Kini
An efficient asymmetric oxidation of sulfides was achieved using (R)-6,6'-dibromo-BINOL as chiral ligand in combination with Ti(OiPr)4 using 70% aqueous tertiary butyl hydroperoxide as oxidant. The resulting sulfoxides had high enantiopurities and go
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a052eca7dec0695215fc6c9816c82e
Autor:
Yuvraj Atmaram Chavan, Girij Pal Singh, Tushar Nandkumar Despande, Dnyaneshwar Tukaram Singare, Yogesh Dadaji Pawar, Purna Chandra Ray
Publikováno v:
Organic Process Research & Development. 22:520-526
The present invention provides process for preparation of dihydroxy benzoquinoline compound (III) comprising reacting dihydroxy isoquinoline compound (IV) or a salt thereof with (2-acetyl-4-methyl-pentyl)-trimethyl-ammonium iodide (V) and further 5 c