Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Giridhar Thiagarajan"'
Autor:
Giridhar Thiagarajan, Hamidreza Ghandehari, S. Sadekar, Dallin Hubbard, Lawrence D. McGill, K. Bartlett, Abhijit Ray
Publikováno v:
International Journal of Pharmaceutics. 456:175-185
Oral delivery of camptothecin has a treatment advantage but is limited by low bioavailability and gastrointestinal toxicity. Poly(amido amine) or PAMAM dendrimers have shown promise as intestinal penetration enhancers, drug solubilizers and drug carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09de31840fc14b11762a825ead2b4333
https://doi.org/10.1016/j.ijpharm.2013.07.071
https://doi.org/10.1016/j.ijpharm.2013.07.071
Autor:
Alexander Malugin, Hamidreza Ghandehari, Giridhar Thiagarajan, Philip J. Moos, Heather Herd, Matthew Honeggar
Publikováno v:
Molecular Pharmaceutics. 10:3242-3252
Understanding the potential toxicities of manufactured nanoconstructs used for drug delivery and biomedical applications may help improve their safety. We sought to determine if surface-modified silica nanoparticles and poly(amido amine) dendrimers e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b608286703417461b88719603479fe8
https://doi.org/10.1021/mp400285u
https://doi.org/10.1021/mp400285u
Autor:
Robert A. Campbell, Soheyl Tadjiki, Amanda E. Brooks, David W. Grainger, Andrew S. Weyrich, Shoeleh Assemi, Giridhar Thiagarajan, Benjamin D. Brooks, Clinton F. Jones, Cheyanne Mulcock, Hamidreza Ghandehari
Publikováno v:
ACS Nano. 6:9900-9910
Poly(amidoamine) (PAMAM) dendrimers are increasingly studied as model nanoparticles for a variety of biomedical applications, notably in systemic administrations. However, with respect to blood contacting applications, amine-terminated dendrimers hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b05fa9edfdc11313da0187a9923f608
https://doi.org/10.1021/nn303472r
https://doi.org/10.1021/nn303472r
Autor:
Giridhar, Thiagarajan
Publikováno v:
Advanced Drug Delivery Reviews. 112:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388a95cde15de0d355874c690317c000
https://doi.org/10.1016/j.addr.2017.06.001
https://doi.org/10.1016/j.addr.2017.06.001
Autor:
Hamid Ghandehari, David W. Grainger, Giridhar Thiagarajan, Kristen Kurtzeborn, Anna Astashkina, Benjamin D. Brooks, Clinton F. Jones
Publikováno v:
Biomaterials. 35(24)
Nanocarriers and nanoparticles remain an intense pharmaceutical and medical imaging technology interest. Their entry into clinical use is hampered by the lack of reliable in vitro models that accurately predict in vivo toxicity. This study evaluates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3511086aeb4fc474cc8a6b5b7ff74ffa
https://pubmed.ncbi.nlm.nih.gov/24814424
https://pubmed.ncbi.nlm.nih.gov/24814424
Publikováno v:
Molecular pharmaceutics. 10(3)
Development of carrier systems to improve oral bioavailability and target drugs to specific sites continues to be an unmet need. The goal of this study was to evaluate the potential of anionic generation (G) 6.5 poly(amido amine) (PAMAM) dendrimers i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da71d5ce3e8d83c6c955cef1af6d2d2
https://pubmed.ncbi.nlm.nih.gov/23286733
https://pubmed.ncbi.nlm.nih.gov/23286733
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 926
The new field of nanotoxicology is steadily emerging in parallel with rapid advances made in nanotechnology to evaluate biological impact of intended and non-intended nanomaterial exposure over time as their human applications constantly increase. Ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::981106e850cac50ce07c7f6c65faadee
https://pubmed.ncbi.nlm.nih.gov/22975969
https://pubmed.ncbi.nlm.nih.gov/22975969
Autor:
Christopher C. Gibson, Andrew S. Weyrich, S. Fazal Mohammad, Benjamin D. Brooks, Dean Y. Li, David W. Grainger, Zechariah Franks, Sivaprasad Sukavaneshvar, Adriana Vieira-de-Abreu, Giridhar Thiagarajan, Robert A. Campbell, Clinton F. Jones, Hamidreza Ghandehari
Publikováno v:
Molecular pharmaceutics. 9(6)
Poly(amidoamine) (PAMAM) dendrimers have been proposed for a variety of biomedical applications and are increasingly studied as model nanomaterials for such use. The dendritic structure features both modular synthetic control of molecular size and sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d512ea34dc1ad0637e7719546da0d055
https://pubmed.ncbi.nlm.nih.gov/22497592
https://pubmed.ncbi.nlm.nih.gov/22497592
Publikováno v:
Methods in Molecular Biology ISBN: 9781627030014
The new field of nanotoxicology is steadily emerging in parallel with rapid advances made in nanotechnology to evaluate biological impact of intended and non-intended nanomaterial exposure over time as their human applications constantly increase. Ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65bd5c0e908da3e7f1d64c0f36134a7f
https://doi.org/10.1007/978-1-62703-002-1_17
https://doi.org/10.1007/978-1-62703-002-1_17
Autor:
Abhijit Ray, S. Sadekar, Alexander J. Burckle, Robert Price, Khaled Greish, Heather Herd, Hamidreza Ghandehari, Hillevi Bauer, Tian Yu, Giridhar Thiagarajan, Arnida Anwar, Dallin Hubbard
Publikováno v:
Nanotoxicology. 6(7)
The influence of size, surface charge and surface functionality of poly(amido amine) dendrimers and silica nanoparticles (SNPs) on their toxicity was studied in immunocompetent mice. After systematic characterization of nanoparticles, they were admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba5db674e9b32fdc2ebe361b13bfe08
https://pubmed.ncbi.nlm.nih.gov/21793770
https://pubmed.ncbi.nlm.nih.gov/21793770