Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Giri, Narasimhan"'
Publikováno v:
mSystems, Vol 9, Iss 10 (2024)
ABSTRACT A key challenge in the analysis of microbiome data is the integration of multi-omic datasets and the discovery of interactions between microbial taxa, their expressed genes, and the metabolites they consume and/or produce. In an effort to im
Externí odkaz:
https://doaj.org/article/4033d4b20a9e4570a0ff60da1453a30c
Autor:
Camilo Valdes, Vitalii Stebliankin, Daniel Ruiz-Perez, Ji In Park, Hajeong Lee, Giri Narasimhan
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Abundance profiles from metagenomic sequencing data synthesize information from billions of sequenced reads coming from thousands of microbial genomes. Analyzing and understanding these profiles can be a challenge since the data they represent are co
Externí odkaz:
https://doaj.org/article/1ac0f57778c14f34ad351acde6704114
Autor:
Punnag Saha, Dipro Bose, Vitalii Stebliankin, Trevor Cickovski, Ratanesh K. Seth, Dwayne E. Porter, Bryan W. Brooks, Kalai Mathee, Giri Narasimhan, Rita Colwell, Geoff I. Scott, Saurabh Chatterjee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract A strong association between exposure to the common harmful algal bloom toxin microcystin and the altered host gut microbiome has been shown. We tested the hypothesis that prior exposure to the cyanotoxin microcystin-LR may alter the host re
Externí odkaz:
https://doaj.org/article/4113e679045a4f84b6bda35bbbf7ee5c
Autor:
Trevor Cickovski, Kalai Mathee, Gloria Aguirre, Gorakh Tatke, Alejandro Hermida, Giri Narasimhan, Melanie Stollstorff
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0273890 (2023)
Attention Deficit Hyperactivity Disorder (ADHD) is an increasingly prevalent neuropsychiatric disorder characterized by hyperactivity, inattention, and impulsivity. Symptoms emerge from underlying deficiencies in neurocircuitry, and recent research h
Externí odkaz:
https://doaj.org/article/fc402609d73d41648c270b3794fa00b0
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Causal inference in biomedical research allows us to shift the paradigm from investigating associational relationships to causal ones. Inferring causal relationships can help in understanding the inner workings of biological processes. Assoc
Externí odkaz:
https://doaj.org/article/0974e667ee9d426d989defda541b8088
Publikováno v:
BMC Bioinformatics, Vol 21, Iss S1, Pp 1-10 (2020)
Abstract Background Partial Least-Squares Discriminant Analysis (PLS-DA) is a popular machine learning tool that is gaining increasing attention as a useful feature selector and classifier. In an effort to understand its strengths and weaknesses, we
Externí odkaz:
https://doaj.org/article/6a907005b0d448f7adfb27c5cfbdf021
Publikováno v:
BMC Genomics, Vol 21, Iss S6, Pp 1-11 (2020)
Abstract Background Microbe-microbe and host-microbe interactions in a microbiome play a vital role in both health and disease. However, the structure of the microbial community and the colonization patterns are highly complex to infer even under con
Externí odkaz:
https://doaj.org/article/95b8ad6722074baeb48d81f5268ea52a
Autor:
Haley R. Martin, Sabrina Sales Martinez, Vitalii Stebliankin, Javier A. Tamargo, Adriana Campa, Giri Narasimhan, Jacqueline Hernandez, Jose A. Bastida Rodriguez, Colby Teeman, Angelique Johnson, Kenneth E. Sherman, Marianna K. Baum
Publikováno v:
Metabolites, Vol 13, Iss 2, p 271 (2023)
The gut–liver axis has been recognized as a potential pathway in which dietary factors may contribute to liver disease in people living with HIV (PLWH). The objective of this study was to explore associations between dietary quality, the fecal micr
Externí odkaz:
https://doaj.org/article/142cdbdc9d974abe95159fc13ee71d91
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S11, Pp 1-9 (2019)
Abstract Background Computing centrality is a foundational concept in social networking that involves finding the most “central” or important nodes. In some biological networks defining importance is difficult, which then creates challenges in fi
Externí odkaz:
https://doaj.org/article/8fc8387b7b67447697221c8f225a82e9
Publikováno v:
Microbiome, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background Several studies have focused on the microbiota living in environmental niches including human body sites. In many of these studies, researchers collect longitudinal data with the goal of understanding not only just the composition
Externí odkaz:
https://doaj.org/article/49d4ae40b99d4c3693ec6e474914baeb