Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Girgis, Obaid"'
Autor:
Girgis Obaid, Shazia Bano, Hanna Thomsen, Susan Callaghan, Nimit Shah, Joseph W. R. Swain, Wendong Jin, Xiadong Ding, Colin G. Cameron, Sherri A. McFarland, Juwell Wu, Mark Vangel, Svetla Stoilova‐McPhie, Jie Zhao, Mari Mino‐Kenudson, Charles Lin, Tayyaba Hasan
Publikováno v:
Advanced Science, Vol 9, Iss 24, Pp n/a-n/a (2022)
Abstract Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits 5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that contribute to treatment resistance, yet depleting the stroma
Externí odkaz:
https://doaj.org/article/0670866fd506442c8ba84eb912ca8dbe
Autor:
Chanda Bhandari, John Fakhry, Menitte Eroy, Jane Junghwa Song, Kimberley Samkoe, Tayyaba Hasan, Kenneth Hoyt, Girgis Obaid
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Fluorescence image-guided surgery (IGS) using antibody conjugates of the fluorophore IRDye800CW have revolutionized the surgical debulking of tumors. Cetuximab, an anti-epidermal growth factor receptor (EGFR) monoclonal antibody, conjugated to IRDye8
Externí odkaz:
https://doaj.org/article/3f8234b1c7cf4b5b93f65c7332661e5e
Autor:
Drashti Shah, Menitte Eroy, John Fakhry, Azophi Moffat, Kevin Fritz, Houston D. Cole, Colin G. Cameron, Sherri A. McFarland, Girgis Obaid
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2426 (2022)
Osmium (Os)-based photosensitizers (PSs) exhibit unique broad, red-shifted absorption, favoring PDT activity at greater tissue depths. We recently reported on a potent Os(II) PS, rac-[Os(phen)2(IP-4T)](Cl)2 (ML18J03) with submicromolar hypoxia activi
Externí odkaz:
https://doaj.org/article/e21ca653a6b24aca8bb09c3f5d9ce9b5
Autor:
Brittany P. Rickard, Marta Overchuk, Girgis Obaid, Mustafa Kemal Ruhi, Utkan Demirci, Suzanne E. Fenton, Janine H. Santos, David Kessel, Imran Rizvi
Publikováno v:
Photochemistry and Photobiology. 99:448-468
Ovarian cancer is the most lethal gynecologic malignancy with a stubborn mortality rate of ~65%. The persistent failure of multiline chemotherapy, and significant tumor heterogeneity, has made it challenging to improve outcomes. A target of increasin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83df4be57d25428857b9a8a73a8997c8
https://doi.org/10.1111/php.13723
https://doi.org/10.1111/php.13723
Autor:
Ling Ma, Akhila Srinivas, Abirami Krishnamurthy, Ximing Zhou, Nimit Subhashbhai Shah, Girgis Obaid, Baowei Fei
Publikováno v:
Label-free Biomedical Imaging and Sensing (LBIS) 2023.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::572fbf77fcd88a46ac31ae4a6cdc1f93
https://doi.org/10.1117/12.2651011
https://doi.org/10.1117/12.2651011
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 786 (2021)
The emergence of biomimetic nanotechnology has seen an exponential rise over the past decade with applications in regenerative medicine, immunotherapy and drug delivery. In the context of nanomedicines activated by near infrared (NIR) photodynamic pr
Externí odkaz:
https://doaj.org/article/72c5d1f6e6a9451984b141387e54096d
Autor:
Sydney Formica, Tayyaba Hasan, Wonho Zhung, Stacey Grimaldo Garcia, Margaret Elizabeth Stanley, Girgis Obaid, Mohammad A. Saad
Publikováno v:
Molecular Pharmaceutics. 19:2549-2563
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease characterized by increased levels of desmoplasia that contributes to reduced drug delivery and poor treatment outcomes. In PDAC, the stromal content can account for up to 90% of the tot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d12a8d5ebc9264a9d0a4b40d007f346
https://doi.org/10.1021/acs.molpharmaceut.2c00260
https://doi.org/10.1021/acs.molpharmaceut.2c00260
Publikováno v:
2022 IEEE International Ultrasonics Symposium (IUS).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff5eea326eda5a87dbd3b0e4016d25d5
https://doi.org/10.1109/ius54386.2022.9957534
https://doi.org/10.1109/ius54386.2022.9957534
Autor:
Mans BROEKGAARDEN, Tristan LE CLAINCHE, Nazareth CARIGGA GUTIERREZ, Núria PUJOL-SOLÉ, Malika KADRI, Chanda BHANDARI, Girgis OBAID, Jean-Luc COLL
Publikováno v:
Photodiagnosis and Photodynamic Therapy. 41:103379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d5599e64cef64f5410dfe939c5d7bc8
https://doi.org/10.1016/j.pdpdt.2023.103379
https://doi.org/10.1016/j.pdpdt.2023.103379
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2451
A hallmark of pancreatic ductal adenocarcinoma (PDAC) is its poor prognosis that stems from a marked resistance to therapy, an invasive nature, and a high metastatic potential. Photodynamic therapy (PDT) is a promising modality for effectively managi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b99526da71f7620b01f436fbcbfb3792
https://pubmed.ncbi.nlm.nih.gov/35505017
https://pubmed.ncbi.nlm.nih.gov/35505017