Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gipsy Majumdar"'
Autor:
Marshall B Elam, Gipsy Majumdar, Khyobeni Mozhui, Ivan C Gerling, Santiago R Vera, Hannah Fish-Trotter, Robert W Williams, Richard D Childress, Rajendra Raghow
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181308 (2017)
Statins, the 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors, are widely prescribed for treatment of hypercholesterolemia. Although statins are generally well tolerated, up to ten percent of statin-treated patients experience myalgia sympt
Externí odkaz:
https://doaj.org/article/f656a1c7cac74a59ac6269e67cfb387b
Autor:
Robert N. O'Meally, Gipsy Majumdar, Marshall B. Elam, Robert N. Cole, Rajendra Raghow, Qingming Dong
Publikováno v:
Molecular and cellular biochemistry. 463(1-2)
Insulin stimulates de novo lipid synthesis in the liver and in cultured hepatocytes via its ability to activate sterol regulatory element-binding protein 1c (SREBP-1c). Although PI3K-AKT-mTORC1-p70S6K-signaling kinases are known to drive feed-forward
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10da0ddcf0df0788c768ae11b6a1d3b3
https://pubmed.ncbi.nlm.nih.gov/31541353
https://pubmed.ncbi.nlm.nih.gov/31541353
Publikováno v:
Analytical Biochemistry. 474:25-27
We combined the TRIzol method of nucleic acid extraction with QIAamp columns to achieve coextraction of RNA and genomic DNA from peripheral blood mononuclear cells (PBMCs) and biopsied skeletal muscle, both stored at -80 °C for many months. Total RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaab7d4aca0c251a90975272fe278859
https://doi.org/10.1016/j.ab.2014.12.021
https://doi.org/10.1016/j.ab.2014.12.021
Publikováno v:
Life Sciences. 83:305-312
Specificity protein 1 (Sp1) belongs to a family of ubiquitously expressed, C2H2-type zinc finger-containing DNA binding proteins that activate or repress transcription of many genes in response to physiological and pathological stimuli. There is emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa93e937e0f26cbfbd5be9d71a85e56
https://doi.org/10.1016/j.lfs.2008.06.024
https://doi.org/10.1016/j.lfs.2008.06.024
Autor:
Rajendra Raghow, Gipsy Majumdar
Publikováno v:
Molecular and cellular biochemistry. 415(1-2)
The pan-histone deacetylase inhibitor (HDACI), trichostatin A (TSA), was shown to normalize interleukin-18-induced cardiac hypertrophy in vivo and in vitro; evidently, this occurred via epigenetic mechanisms that profoundly altered cardiac gene expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae8aa0baeec038d8238199774256f68
https://pubmed.ncbi.nlm.nih.gov/26946427
https://pubmed.ncbi.nlm.nih.gov/26946427
O-glycosylation of Sp1 and transcriptional regulation of the calmodulin gene by insulin and glucagon
Autor:
Antonio Martinez-Hernandez, Rajendra Raghow, Gipsy Majumdar, Rosalind Pitpitan Candelaria, Solomon S. Solomon, Ashley D. Harmon
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 285:E584-E591
Both insulin and glucagon stimulate steady-state levels of Sp1 transcription factor, but only insulin stimulates transcription of the calmodulin (CaM) gene in liver. Because O-glycosylation of Sp1 by O-linked N-acetylglucosamine ( O-GlcNAc) is though
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bbd74de4ff88496af59f8250caa551
https://doi.org/10.1152/ajpendo.00140.2003
https://doi.org/10.1152/ajpendo.00140.2003
Publikováno v:
BMC Genomics
BMC Genomics, Vol 13, Iss 1, p 709 (2012)
BMC Genomics, Vol 13, Iss 1, p 709 (2012)
Background We have shown previously that pan-HDAC inhibitors (HDACIs) m-carboxycinnamic acid bis-hydroxamide (CBHA) and trichostatin A (TSA) attenuated cardiac hypertrophy in BALB/c mice by inducing hyper-acetylation of cardiac chromatin that was acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f7846b505b61f67b4e2acac9dc7205
https://doi.org/10.1186/1471-2164-13-709
https://doi.org/10.1186/1471-2164-13-709
We investigated the genome-wide consequences of pan-histone deacetylase inhibitors (HDACIs) trichostatin A (TSA) and m-carboxycinnamic acid bis-hydroxamide (CBHA) in the hearts of BALB/c mice eliciting hypertrophy in response to interleukin-18 (IL-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfaf58d9523cf5af004d9f4f22fe0bd
https://europepmc.org/articles/PMC3297084/
https://europepmc.org/articles/PMC3297084/
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 10, Iss Suppl 7, p A14 (2009)
BMC Bioinformatics, Vol 10, Iss Suppl 7, p A14 (2009)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc380afb72cd0e05222b1991c23b7cdb
https://doi.org/10.1186/1471-2105-10-s7-a14
https://doi.org/10.1186/1471-2105-10-s7-a14
Publikováno v:
Cellular Signalling. 2:521-530
The requirement for co-stimulatory molecules in T-cell stimulation by mitogens and superantigens in the absence of antigen-presenting cells (APC) was investigated. Phytohemagglutinin (PHA) induced interleukin (IL)-2 receptor (IL-2R) expression on pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010e5f4bdbaae4b8e022d93af41f29b7
https://doi.org/10.1016/0898-6568(90)90074-k
https://doi.org/10.1016/0898-6568(90)90074-k