Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Giovanny Rodríguez-Blanco"'
Autor:
Xuan Wang-Kan, Giovanny Rodríguez-Blanco, Andrew D. Southam, Catherine L. Winder, Warwick B. Dunn, Alasdair Ivens, Laura J. V. Piddock
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Multidrug-resistant Gram-negative bacteria pose a global threat to human health. The AcrB efflux pump confers inherent and evolved drug resistance to EnterobacteralesEscherichia coliSalmonella enterica
Externí odkaz:
https://doaj.org/article/986045510b894ff9937b9ecb4c487418
Autor:
Tobias Ackermann, Engy Shokry, Ruhi Deshmukh, Jayanthi Anand, Laura C A Galbraith, Louise Mitchell, Giovanny Rodriguez-Blanco, Victor H Villar, Britt Amber Sterken, Colin Nixon, Sara Zanivan, Karen Blyth, David Sumpton, Saverio Tardito
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 11, Pp 2749-2774 (2024)
Abstract The limited availability of therapeutic options for patients with triple-negative breast cancer (TNBC) contributes to the high rate of metastatic recurrence and poor prognosis. Ferroptosis is a type of cell death caused by iron-dependent lip
Externí odkaz:
https://doaj.org/article/10957b6640e845b78b80022107f4701b
Autor:
Geert J.L.H. van Leenders, Diederick Duijvesz, Lennard J. M. Dekker, A. Marije Hoogland, Esther I. Verhoef, Giovanny Rodríguez-Blanco, Theo M. Luider, Guido Jenster, Monique J. Roobol
Publikováno v:
The Prostate
Prostate, 79(9), 1032-1042. Wiley-Liss Inc.
Prostate, 79(9), 1032-1042. Wiley-Liss Inc.
textabstractAbstract Background: Proteomic profiling of extracellular vesicles (EVs) from prostate cancer (PCa) and normal prostate cell lines, led to the identification of new candidate PCa markers. These proteins included the nuclear exportin prote
Autor:
Theo M. Luider, Peter A. E. Sillevis Smitt, Guido Jenster, Chris H. Bangma, Geert J.L.H. van Leenders, Esther I. Verhoef, Charlotte F. Kweldam, A. Marije Hoogland, Diederick Duijvesz, Peter C. Burgers, Lona Zeneyedpour, Giovanny Rodríguez-Blanco, Lennard J. M. Dekker
Publikováno v:
Oncotarget
Oncotarget, 9(92), 36444-36456. Impact Journals LLC
Oncotarget, 9(92), 36444-36456. Impact Journals LLC
Although many patients are cured from prostate cancer (PCa) by surgery only, there are still patients who will experience rising prostate-specific antigen (PSA) levels after surgery, a condition known as biochemical recurrence (BCR). Novel protein pr
Autor:
Beatrice Anna Brugger, Lena Neuper, Jacqueline Guettler, Désirée Forstner, Stefan Wernitznig, Daniel Kummer, Freya Lyssy, Julia Feichtinger, Julian Krappinger, Amin El-Heliebi, Lilli Bonstingl, Gerit Moser, Giovanny Rodriguez-Blanco, Olaf A. Bachkönig, Benjamin Gottschalk, Michael Gruber, Olivia Nonn, Florian Herse, Stefan Verlohren, Hans-Georg Frank, Nirav Barapatre, Cornelia Kampfer, Herbert Fluhr, Gernot Desoye, Martin Gauster
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-21 (2023)
Abstract Background The human placenta, a tissue with a lifespan limited to the period of pregnancy, is exposed to varying shear rates by maternal blood perfusion depending on the stage of development. In this study, we aimed to investigate the effec
Externí odkaz:
https://doaj.org/article/bca08208558c4bd4873129488493152b
Autor:
Giovanny Rodríguez-Blanco, Peter C. Burgers, Guido Jenster, Theo M. Luider, Jan J. N. IJzermans, Chris H. Bangma, Lennard J. M. Dekker, Mark F. Wildhagen, Ellen A. M. Schenk-Braat
Publikováno v:
The Prostate. 74:618-627
BACKGROUND Arachidonic acid (AA) pathway has been shown to play a role in the development and progression of prostate cancer (PCa). In this study we aimed to assess the changes in concentrations of hydroxyeicosatetraenoic acids (HETEs) in serum sampl
Publikováno v:
ChemPlusChem. 78:1184-1189
Carboxylate-substituted superhalogens of the type RCOOMX2 - (M=Mg, Ca, Sr, Ba, Mn, Co, Ni, Zn; X=Cl, Br) are easily accessible in the gas phase by electrospray ionisation. Their collision-induced dissociation (CID) characteristics have been probed by
Autor:
Joy Edwards-Hicks, Huizhong Su, Maurizio Mangolini, Kubra K. Yoneten, Jimi Wills, Giovanny Rodriguez-Blanco, Christine Young, Kevin Cho, Heather Barker, Morwenna Muir, Ania Naila Guerrieri, Xue-Feng Li, Rachel White, Piotr Manasterski, Elena Mandrou, Karen Wills, Jingyu Chen, Emily Abraham, Kianoosh Sateri, Bin-Zhi Qian, Peter Bankhead, Mark Arends, Noor Gammoh, Alex von Kriegsheim, Gary J. Patti, Andrew H. Sims, Juan Carlos Acosta, Valerie Brunton, Kamil R. Kranc, Maria Christophorou, Erika L. Pearce, Ingo Ringshausen, Andrew J. Finch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
MYC activation can sensitise cells to apoptosis upon glutamine withdrawal. Here the authors show that MYC activation enhances global transcription and translation that creates a metabolic demand, while glutamine limitation causes a metabolic demand a
Externí odkaz:
https://doaj.org/article/f58e694b2f6c429fb6bed6c1ae69a6f7
Autor:
Aitor Almanza, Katarzyna Mnich, Arnaud Blomme, Claire M. Robinson, Giovanny Rodriguez-Blanco, Sylwia Kierszniowska, Eoghan P. McGrath, Matthieu Le Gallo, Eleftherios Pilalis, Johannes V. Swinnen, Aristotelis Chatziioannou, Eric Chevet, Adrienne M. Gorman, Afshin Samali
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
IRE1α cleaves several mRNAs upon accumulation of misfolded proteins. Here the authors show that active IRE1α cleaves DGAT2 mRNA encoding the rate-limiting enzyme in the synthesis of triacylglycerols, suggesting a role of IRE1α in reprogramming lip
Externí odkaz:
https://doaj.org/article/5880a9d0a80d435dbe79e1dfb4bc9b6f
Autor:
Giovanny, Rodríguez-Blanco, Karl J, Jobst, Theo M, Luider, Johan K, Terlouw, Peter C, Burgers
Publikováno v:
ChemPlusChem. 78(9)
Carboxylate-substituted superhalogens of the type RCOOMX