Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Giovanni Zummo"'
Autor:
Giovanni Tomasello, Margherita Mazzola, Angelo Leone, Emanuele Sinagra, Giovanni Zummo, Felicia Farina, Provvidenza Damiani, Francesco Cappello, Alice Gerges Geagea, Abdo Jurjus, Tarek Bou Assi, Massimiliano Messina, Francesco Carini
Publikováno v:
Biomedical Papers, Vol 160, Iss 4, Pp 461-466 (2016)
Background: Microbiota refers to the population of microorganisms (bacteria, viruses and fungi) that inhabit the entire gastrointestinal tract, more particularly the colon whose role is to maintain the integrity of the intestinal mucosa and control t
Externí odkaz:
https://doaj.org/article/023ba3ca347c4f87b9cf01089de0b1c2
Autor:
Simona Corrao, Giampiero La Rocca, Rita Anzalone, Lorenzo Marasà, Felicia Farina, Giovanni Zummo, Francesco Cappello
Publikováno v:
Oncology Reviews, Vol 1, Iss 4, Pp 225-232 (2011)
Oesophageal cancer (OC) is one of the most common and severe forms of tumor. A wider knowledge of molecular mechanisms which lead to a normal epithelium becoming a neoplasm may reveal new strategies to improve treatment and outcome of this disease. I
Externí odkaz:
https://doaj.org/article/3abedb4a3f194271976eba577d1a4243
Autor:
Fabio Bucchieri, Antonella Marino Gammazza, Alessandro Pitruzzella, Alberto Fucarino, Felicia Farina, Peter Howarth, Stephen T Holgate, Giovanni Zummo, Donna E Davies
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120510 (2015)
BackgroundEpidemiologic studies have demonstrated important links between air pollution and asthma. Amongst these pollutants, environmental cigarette smoke is a risk factor both for asthma pathogenesis and exacerbation. As the barrier to the inhaled
Externí odkaz:
https://doaj.org/article/378bc17dfd8547daaeb46cae1943c8ee
Autor:
Silvia Vilasi, Rita Carrotta, Maria Rosalia Mangione, Claudia Campanella, Fabio Librizzi, Loredana Randazzo, Vincenzo Martorana, Antonella Marino Gammazza, Maria Grazia Ortore, Annalisa Vilasi, Gabriella Pocsfalvi, Giosalba Burgio, Davide Corona, Antonio Palumbo Piccionello, Giovanni Zummo, Donatella Bulone, Everly Conway de Macario, Alberto J L Macario, Pier Luigi San Biagio, Francesco Cappello
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97657 (2014)
It has been established that Hsp60 can accumulate in the cytosol in various pathological conditions, including cancer and chronic inflammatory diseases. Part or all of the cytosolic Hsp60 could be naïve, namely, bear the mitochondrial import signal
Externí odkaz:
https://doaj.org/article/8ee4bc6c32134030a3350365e267331b
Autor:
Rosario Barone, Filippo Macaluso, Patrizia Catanese, Antonella Marino Gammazza, Luigi Rizzuto, Paola Marozzi, Giuseppe Lo Giudice, Tomaso Stampone, Francesco Cappello, Giuseppe Morici, Giovanni Zummo, Felicia Farina, Valentina Di Felice
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79686 (2013)
A new role for fat supplements, in particular conjugated linoleic acid (CLA), has been delineated in steroidogenesis, although the underlying molecular mechanisms have not yet been elucidated. The aims of the present study were to identify the pathwa
Externí odkaz:
https://doaj.org/article/1e226cd612e840e695e5bb97e7800acc
Autor:
Claudia Campanella, Fabio Bucchieri, Anna M Merendino, Alberto Fucarino, Giosalba Burgio, Davide F V Corona, Giovanna Barbieri, Sabrina David, Felicia Farina, Giovanni Zummo, Everly Conway de Macario, Alberto J L Macario, Francesco Cappello
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42008 (2012)
BACKGROUND: In a previous work we showed for the first time that human tumor cells secrete Hsp60 via exosomes, which are considered immunologically active microvesicles involved in tumor progression. This finding raised questions concerning the route
Externí odkaz:
https://doaj.org/article/93f36aaee75f436ca2aae23576f7d0ed
Autor:
Francesco Cappello, Gaetano Caramori, Claudia Campanella, Chiara Vicari, Isabella Gnemmi, Andrea Zanini, Antonio Spanevello, Armando Capelli, Giampiero La Rocca, Rita Anzalone, Fabio Bucchieri, Silvestro Ennio D'Anna, Fabio L M Ricciardolo, Paola Brun, Bruno Balbi, Mauro Carone, Giovanni Zummo, Everly Conway de Macario, Alberto J L Macario, Antonino Di Stefano
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e28200 (2011)
BackgroundIt is increasingly clear that some heat shock proteins (Hsps) play a role in inflammation. Here, we report results showing participation of Hsp60 in the pathogenesis of chronic obstructive pulmonary diseases (COPD), as indicated by data fro
Externí odkaz:
https://doaj.org/article/17adeac62af342d3ae37bd8812d2dade
Autor:
Anna M Merendino, Fabio Bucchieri, Claudia Campanella, Vito Marcianò, Anna Ribbene, Sabrina David, Giovanni Zummo, Giosalba Burgio, Davide F V Corona, Everly Conway de Macario, Alberto J L Macario, Francesco Cappello
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9247 (2010)
Hsp60, a Group I mitochondrial chaperonin, is classically considered an intracellular chaperone with residence in the mitochondria; nonetheless, in the last few years it has been found extracellularly as well as in the cell membrane. Important questi
Externí odkaz:
https://doaj.org/article/5a5c169e599749fc81920d472e6c47c6
Autor:
Francesco Cappello, Everly Conway de Macario, Valentina Di Felice, Giovanni Zummo, Alberto J L Macario
Publikováno v:
PLoS Pathogens, Vol 5, Iss 8, p e1000552 (2009)
Chlamydia trachomatis (CT) infection is one of the most common causes of reproductive tract diseases and infertility. CT-Hsp60 is synthesized during infection and is released in the bloodstream. As a consequence, immune cells will produce anti-CT-Hsp
Externí odkaz:
https://doaj.org/article/56bf6237a0124f778d95d435314be999
Autor:
Alberto Fucarino, Donna E. Davies, Massimo Cajozzo, Vito Marcianò, Roberto Marchese, Celeste Caruso Bavisotto, Antonella Marino Gammazza, Fabio Bucchieri, Giorgio Lo Iacono, Stephen T. Holgate, Giovanni Zummo, Alessandro Pitruzzella
Publikováno v:
Experimental Lung Research. 43:82-92
Background/Aim: Epithelial-mesenchymal communication plays a key role in tissue homeostasis and abnormal signaling contributes to chronic airways disease such as COPD. Most in vitro models are limited in complexity and poorly represent this epithelia