Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Giovanni Tonon"'
Autor:
Federico Di Marco, Francesca Nicola, Francesca Giannese, Fabio Saliu, Giovanni Tonon, Stefano de Pretis, Daniela M. Cirillo, Nicola I. Lorè
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract Co-localization of spatial transcriptome information of host and pathogen can revolutionize our understanding of microbial pathogenesis. Here, we aimed to demonstrate that customized bacterial probes can be successfully used to identify host
Externí odkaz:
https://doaj.org/article/8471cbe94abf419c81a8790f8f45a6d0
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8651 (2024)
This review highlights significant advancements in antibody–drug conjugates (ADCs) equipped with metal-based and nature-inspired payloads, focusing on synthetic strategies for antibody conjugation. Traditional methods such us maleimide and succinim
Externí odkaz:
https://doaj.org/article/9d3025f8aa2f4ebb984a1f48f0cd014b
Autor:
Alice Bergamini, Barbara Camisa, Fabio Ciceri, Chiara Bonini, Monica Casucci, Beatrice Greco, Federica Pedica, Chiara Balestrieri, Laura Falcone, Miriam Redegalli, Elena Tiziano, Camilla Sirini, Giovanni Tonon, Rita El Khoury, Oronzina Botrugno
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/6820359e0066459fad42c748e3f33dd2
Autor:
Pasquale Tomaiuolo, Ignazio Stefano Piras, Simona Baghai Sain, Chiara Picinelli, Marco Baccarin, Paola Castronovo, Marco J. Morelli, Dejan Lazarevic, Maria Luisa Scattoni, Giovanni Tonon, Antonio M. Persico
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental condition with onset in early childhood, still diagnosed only through clinical observation due to the lack of laboratory biomarkers. Early detection strategies would be especially useful
Externí odkaz:
https://doaj.org/article/145eb5975dc34ca795f6127c1f2c4542
Autor:
Piera Tocci, Celia Roman, Rosanna Sestito, Valeriana Di Castro, Andrea Sacconi, Ivan Molineris, Francesca Paolini, Mariantonia Carosi, Giovanni Tonon, Giovanni Blandino, Anna Bagnato
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract PARP inhibitors (PARPi) have changed the treatment paradigm of high-grade serous ovarian cancer (HG-SOC). However, the impact of this class of inhibitors in HG-SOC patients with a high rate of TP53 mutations is limited, highlighting the need
Externí odkaz:
https://doaj.org/article/97d7338baecc4cf38a82c60cc89b3d86
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102176- (2023)
Summary: scGET-seq simultaneously profiles euchromatin and heterochromatin. scGET-seq exploits the concurrent action of transposase Tn5 and its hybrid form TnH, which targets H3K9me3 domains. Here we present a step-by-step protocol to profile single
Externí odkaz:
https://doaj.org/article/0640a8dbb7b34c41a75caaec52044b96
Autor:
Enrico Lavezzo, Monia Pacenti, Laura Manuto, Caterina Boldrin, Margherita Cattai, Marco Grazioli, Federico Bianca, Margherita Sartori, Federico Caldart, Gioele Castelli, Michele Nicoletti, Eleonora Nieddu, Elisa Salvadoretti, Beatrice Labella, Ludovico Fava, Maria Cristina Vanuzzo, Vittoria Lisi, Maria Antonello, Carmela Ileana Grimaldi, Chiara Zulian, Claudia Del Vecchio, Mario Plebani, Andrea Padoan, Daniela Maria Cirillo, Alessandra R. Brazzale, Giovanni Tonon, Stefano Toppo, Ilaria Dorigatti, Andrea Crisanti
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background The continuous emergence of SARS-CoV-2 variants of concern (VOC) with immune escape properties, such as Delta (B.1.617.2) and Omicron (B.1.1.529), questions the extent of the antibody-mediated protection against the virus. Here we
Externí odkaz:
https://doaj.org/article/aa024ed0ba2b40198fd34c511bfa76de
Autor:
Alessia Lai, Annalisa Bergna, Stefano Toppo, Marina Morganti, Stefano Menzo, Valeria Ghisetti, Bianca Bruzzone, Mauro Codeluppi, Vito Fiore, Emmanuele Venanzi Rullo, Guido Antonelli, Loredana Sarmati, Gaetano Brindicci, Annapaola Callegaro, Caterina Sagnelli, Daniela Francisci, Ilaria Vicenti, Arianna Miola, Giovanni Tonon, Daniela Cirillo, Ilaria Menozzi, Sara Caucci, Francesco Cerutti, Andrea Orsi, Roberta Schiavo, Sergio Babudieri, Giuseppe Nunnari, Claudio M. Mastroianni, Massimo Andreoni, Laura Monno, Davide Guarneri, Nicola Coppola, Andrea Crisanti, Massimo Galli, Gianguglielmo Zehender, SCIRE-SARS-CoV-2 Italian Research Enterprise-Collaborative Group
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The aims of this study were to characterize new SARS-CoV-2 genomes sampled all over Italy and to reconstruct the origin and the evolutionary dynamics in Italy and Europe between February and June 2020. The cluster analysis showed only small
Externí odkaz:
https://doaj.org/article/e2668e98ca024562b6edcfdf26a16fa8
Aging, inflammation and DNA damage in the somatic testicular niche with idiopathic germ cell aplasia
Autor:
Massimo Alfano, Anna Sofia Tascini, Filippo Pederzoli, Irene Locatelli, Manuela Nebuloni, Francesca Giannese, Jose Manuel Garcia-Manteiga, Giovanni Tonon, Giada Amodio, Silvia Gregori, Alessandra Agresti, Francesco Montorsi, Andrea Salonia
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Molecular mechanisms associated with human germ cell aplasia in infertile men remain undefined. Here the authors perform single-cell transcriptome profiling to highlight differentially expressed genes and pathways in each somatic cell type in testes
Externí odkaz:
https://doaj.org/article/72d44dea6e06424a96786fa8a4b23932
Autor:
Rachel M. Gittelman, Enrico Lavezzo, Thomas M. Snyder, H. Jabran Zahid, Cara L. Carty, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola I. Lorè, Dejan Lazarević, Daniela M. Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S. Robins, Andrea Crisanti, Giovanni Tonon
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
T cells play a prominent role in orchestrating the immune response to viral diseases, but their role in the clinical presentation and subsequent immunity to SARS-CoV-2 infection remains poorly understood. As part of a population-based survey of the m
Externí odkaz:
https://doaj.org/article/ef4ff663260a45f7ba60d15fe32db9e4