Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Giovanni Stefano Ugolini"'
Autor:
Rajesh Kumari, Ji Won Lim, Matthew Ryan Sullivan, Rachel Malampy, Connor Baush, Irina Smolina, Howard Robin, Vadim V. Demidov, Giovanni Stefano Ugolini, Jared R. Auclair, Tania Konry
Publikováno v:
Diagnostics, Vol 12, Iss 9, p 2252 (2022)
SARS-CoV-2 has remained a global health burden, primarily due to the continuous evolution of different mutant strains. These mutations present challenges to the detection of the virus, as the target genes of qPCR, the standard diagnostic method, may
Externí odkaz:
https://doaj.org/article/54e8372ae5da4abc91ca8cb6eb5f2f82
Autor:
Angelo Iannielli, Giovanni Stefano Ugolini, Chiara Cordiglieri, Simone Bido, Alicia Rubio, Gaia Colasante, Marco Valtorta, Tommaso Cabassi, Marco Rasponi, Vania Broccoli
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4646-4656.e4 (2019)
Summary: Stem cell-derived neurons are generally obtained in mass cultures that lack both spatial organization and any meaningful connectivity. We implement a microfluidic system for long-term culture of human neurons with patterned projections and s
Externí odkaz:
https://doaj.org/article/6c19f59060884387bf61e15b4feb78ac
Autor:
Giovanni Stefano Ugolini, Andrea Pavesi, Marco Rasponi, Gianfranco Beniamino Fiore, Roger Kamm, Monica Soncini
Publikováno v:
eLife, Vol 6 (2017)
Upon cardiac pathological conditions such as ischemia, microenvironmental changes instruct a series of cellular responses that trigger cardiac fibroblasts-mediated tissue adaptation and inflammation. A comprehensive model of how early environmental c
Externí odkaz:
https://doaj.org/article/103adf0b14dd41708342ea26dd00dae2
Autor:
Giovanni Stefano Ugolini, Daniela Cruz-Moreira, Roberta Visone, Alberto Redaelli, Marco Rasponi
Publikováno v:
Micromachines, Vol 7, Iss 12, p 233 (2016)
Microfluidics and microfabrication have recently been established as promising tools for developing a new generation of in vitro cell culture microdevices. The reduced amounts of reagents employed within cell culture microdevices make them particular
Externí odkaz:
https://doaj.org/article/924497237a1f4ae6917c3a15306106c7
Autor:
Sagar N. Agnihotri, Giovanni Stefano Ugolini, Matthew Ryan Sullivan, Yichao Yang, Agustin De Ganzó, Ji Won Lim, Tania Konry
Publikováno v:
Lab on a chip. 22(17)
Most common methods of cellular analysis employ the top-down approach (investigating proteomics or genomics directly), thereby destroying the cell, which does not allow the possibility of using the same cell to correlate genomics with functional assa
Autor:
Mattia, Ballerini, Mohammad, Jouybar, Andrea, Mainardi, Marco, Rasponi, Giovanni Stefano, Ugolini
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2373
A relevant number of organ-on-chips is aimed at modeling epithelial/endothelial interfaces between tissue compartments. These barriers help tissue function either by protecting (e.g., endothelial blood-brain barrier) or by orchestrating relevant mole
Autor:
Anna Marsano, Andrea Mainardi, Paola Occhetta, Giovanni Stefano Ugolini, Gregory Reid, Diana Robles Diaz, Roberta Visone, Francesca Giulia Carminati, Giuseppe Isu, Marco Rasponi
Publikováno v:
Lab on a Chip
Cardiac fibrosis is a maladaptive remodeling of the myocardium hallmarked by contraction impairment and excessive extracellular matrix deposition (ECM). The disease progression, nevertheless, remains poorly understood and present treatments are not c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d3e12cfb8ccacc101e4d7290c574ad
http://hdl.handle.net/11311/1186204
http://hdl.handle.net/11311/1186204
Autor:
Matthew R. Sullivan, Saheli Sarkar, Seamus Mckenney, Giovanni Stefano Ugolini, Tania Konry, Evan Carlton Smith, Wenjing Kang
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-9 (2020)
The inhibition of the PD1/PDL1 pathway has led to remarkable clinical success for cancer treatment in some patients. Many, however, exhibit little to no response to this treatment. To increase the efficacy of PD1 inhibition, additional checkpoint inh
Autor:
Smadar Cohen, Giovanni Stefano Ugolini, Ilana Berger Fridman, Virginia VanDelinder, Tania Konry
Publikováno v:
Biofabrication. 13(3)
Replication of physiological oxygen levels is fundamental for modeling human physiology and pathology in in vitro models. Environmental oxygen levels, applied in most in vitro models, poorly imitate the oxygen conditions cells experience in vivo, whe
Autor:
Jian-ping Xia, Kaichun Yang, Tania Konry, Ruoyu Zhong, Tony Jun Huang, Giovanni Stefano Ugolini, Jinxin Zhang, Shujie Yang, Ty Downing Naquin
Publikováno v:
Small. 17:2170240