Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Giovanni PRINCIPATO"'
Autor:
Giulia Occhipinti, Emanuela Romagnoli, Matteo Santoni, Alessia Cimadamore, Giulia Sorgentoni, Monia Cecati, Matteo Giulietti, Nicola Battelli, Alessandro Maccioni, Nadia Storti, Liang Cheng, Giovanni Principato, Rodolfo Montironi, Francesco Piva
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
About 75% of all breast cancers are hormone receptor-positive (HR+). However, the efficacy of endocrine therapy is limited due to the high rate of either pre-existing or acquired resistance. In this work we reconstructed the pathways around estrogen
Externí odkaz:
https://doaj.org/article/b44af9987ced4980a6b469e387bbac78
Autor:
Riccardo Giampieri, Francesco Piva, Giulia Occhipinti, Alessandro Bittoni, Alessandra Righetti, Silvia Pagliaretta, Alberto Murrone, Francesca Bianchi, Consuelo Amantini, Matteo Giulietti, Giulia Ricci, Giovanni Principato, Giorgio Santoni, Rossana Berardi, Stefano Cascinu
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215990 (2019)
IntroductionPancreatic ductal adenocarcinoma is associated to dismal prognosis despite the use of palliative chemotherapy, partly due to the lack of knowledge of biological processes underlying disease progression. Exosomes have been identified as bi
Externí odkaz:
https://doaj.org/article/0ee1286d0b3740d88afd27936be5e4ae
Autor:
Matteo Giulietti, Giulia Occhipinti, Alessandra Righetti, Massimo Bracci, Alessandro Conti, Annamaria Ruzzo, Elisabetta Cerigioni, Tiziana Cacciamani, Giovanni Principato, Francesco Piva
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Bladder cancer is a very common malignancy. Although new treatment strategies have been developed, the identification of new therapeutic targets and reliable diagnostic/prognostic biomarkers for bladder cancer remains a priority. Generally, they are
Externí odkaz:
https://doaj.org/article/3fe459d5ba3447979f6b6f1d5b9d6309
Autor:
Laura Cianfruglia, Andrea Perrelli, Claudia Fornelli, Alessandro Magini, Stefania Gorbi, Anna Maria Salzano, Cinzia Antognelli, Francesca Retta, Valerio Benedetti, Paola Cassoni, Carla Emiliani, Giovanni Principato, Andrea Scaloni, Tatiana Armeni, Saverio Francesco Retta
Publikováno v:
Antioxidants, Vol 8, Iss 1, p 27 (2019)
Loss-of-function mutations in the KRIT1 gene are associated with the pathogenesis of cerebral cavernous malformations (CCMs), a major cerebrovascular disease still awaiting therapies. Accumulating evidence demonstrates that KRIT1 plays an important r
Externí odkaz:
https://doaj.org/article/25be907905c1464c8f1b05aaaeb7ccee
Autor:
Lorena Urbanelli, Alessandro Magini, Luisa Ercolani, Krizia Sagini, Alice Polchi, Brunella Tancini, Alessandro Brozzi, Tatiana Armeni, Giovanni Principato, Carla Emiliani
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89485 (2014)
The expression of constitutively active H-RasV12 oncogene has been described to induce proliferative arrest and premature senescence in many cell models. There are a number of studies indicating an association between senescence and lysosomal enzyme
Externí odkaz:
https://doaj.org/article/e35abbce096442dab9cf411f44a7e963
Autor:
Tatiana Armeni, Luisa Ercolani, Lorena Urbanelli, Alessandro Magini, Francesca Magherini, Armanda Pugnaloni, Francesco Piva, Alessandra Modesti, Carla Emiliani, Giovanni Principato
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52151 (2012)
H-Ras oncogene requires deregulation of additional oncogenes or inactivation of tumor suppressor proteins to increase cell proliferation rate and transform cells. In fact, the expression of the constitutively activated H-RasV12 induces cell growth ar
Externí odkaz:
https://doaj.org/article/a46c62e317d44a6f995b297a448da801
Autor:
Matteo Giulietti, Giovanni Principato, Berina Sabanovic, Alessandra Righetti, Francesco Piva, Giulia Occhipinti
Publikováno v:
Journal of Oncology
Journal of Oncology, Vol 2019 (2019)
Journal of Oncology, Vol 2019 (2019)
CXCL12 is a chemokine that acts through CXCR4 and ACKR3 receptors and plays a physiological role in embryogenesis and haematopoiesis. It has an important role also in tumor development, since it is released by stromal cells of tumor microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e255275335ede4f23d4d1baae729d734
https://doi.org/10.1155/2019/9681698
https://doi.org/10.1155/2019/9681698
Publikováno v:
Carcinogenesis. 39:1016-1025
High mortality and low survival rates for pancreatic ductal adenocarcinoma (PDAC) mainly result from the delay in diagnosis and treatment. Therefore, there is an urgent need to identify early PDAC biomarkers and new therapeutic targets. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c86ded3ea93c977b426f22081e576a
https://doi.org/10.1093/carcin/bgy069
https://doi.org/10.1093/carcin/bgy069
Autor:
Tatiana Armeni, Giovanni Principato
Publikováno v:
The First Outstanding 50 Years of “Università Politecnica delle Marche” ISBN: 9783030338312
Glutathione is a very ancient molecule widely distributed in aerobic cells and organisms, either prokaryotes or eukaryotes. Since glutathione in not found in anaerobic cells it could have evolved in the course of the adaptation to the presence of oxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83e5ea3a987d2fc6a8bab4d6e530a6de
https://doi.org/10.1007/978-3-030-33832-9_28
https://doi.org/10.1007/978-3-030-33832-9_28
Autor:
Giulia Ricci, Alessandra Righetti, Alberto Murrone, Francesca Bianchi, Francesco Piva, Consuelo Amantini, Riccardo Giampieri, Giulia Occhipinti, Silvia Pagliaretta, Alessandro Bittoni, Rossana Berardi, Stefano Cascinu, Giovanni Principato, Matteo Giulietti, Giorgio Santoni
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0215990 (2019)
PLoS ONE, Vol 14, Iss 5, p e0215990 (2019)
IntroductionPancreatic ductal adenocarcinoma is associated to dismal prognosis despite the use of palliative chemotherapy, partly due to the lack of knowledge of biological processes underlying disease progression. Exosomes have been identified as bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587fcab91321e03104d8b9462a80d44b
http://europepmc.org/articles/PMC6497273
http://europepmc.org/articles/PMC6497273