Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Giovanni Di Bernardo"'
Autor:
Nicola Alessio, Domenico Aprile, Gianfranco Peluso, Valeria Mazzone, Deanira Patrone, Giovanni Di Bernardo, Umberto Galderisi
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Cells that are exposed to harmful genetic damage, either from internal or external sources, may undergo senescence if they are unable to repair their DNA. Senescence, characterized by a state of irreversible growth arrest, can spread to neig
Externí odkaz:
https://doaj.org/article/e598facae67c43619dbd84bedf338c04
Autor:
Yo Oguma, Nicola Alessio, Domenico Aprile, Mari Dezawa, Gianfranco Peluso, Giovanni Di Bernardo, Umberto Galderisi
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract DNA damage resulting from genotoxic injury can initiate cellular senescence, a state characterized by alterations in cellular metabolism, lysosomal activity, and the secretion of factors collectively known as the senescence-associated secret
Externí odkaz:
https://doaj.org/article/0187a4331ecb43a4bf868a3c3308f6ca
Publikováno v:
Methods and Protocols, Vol 7, Iss 4, p 52 (2024)
The word “secretome” was first used to describe the proteins that cells secrete under different circumstances; however, recent studies have proven the existence of other molecules such as RNA and chemical compounds in the secretome. The study of
Externí odkaz:
https://doaj.org/article/46b357a25a9d4c8dab2f3b776de49fa3
Autor:
Nicola Alessio, Tiziana Squillaro, Giovanni Di Bernardo, Giovanni Galano, Roberto De Rosa, Mariarosa AB Melone, Gianfranco Peluso, Umberto Galderisi
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/7b745b3eb045476daf1c4841cc4766de
Autor:
Sura Hilal Ahmed Al Sammarraie, Domenico Aprile, Ilaria Meloni, Nicola Alessio, Francesca Mari, Marianna Manata, Caterina Lo Rizzo, Giovanni Di Bernardo, Gianfranco Peluso, Alessandra Renieri, Umberto Galderisi
Publikováno v:
Cells, Vol 12, Iss 7, p 977 (2023)
Although adult stem cells may be useful for studying tissue-specific diseases, they cannot be used as a general model for investigating human illnesses given their limited differentiation potential. Multilineage-differentiating stress-enduring (Muse)
Externí odkaz:
https://doaj.org/article/c16c4b43b6eb472684b97b601750befd
Autor:
Serife Ayaz-Guner, Nicola Alessio, Mustafa B. Acar, Domenico Aprile, Servet Özcan, Giovanni Di Bernardo, Gianfranco Peluso, Umberto Galderisi
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background The term mesenchymal stromal cells (MSCs) designates an assorted cell population comprised of stem cells, progenitor cells, fibroblasts, and stromal cells. MSCs contribute to the homeostatic maintenance of many organs through para
Externí odkaz:
https://doaj.org/article/aa65bdb2f53049eea9e488f65b6fd025
Autor:
Mustafa Burak Acar, Şerife Ayaz-Güner, Zeynep Gunaydin, Musa Karakukcu, Gianfranco Peluso, Giovanni Di Bernardo, Servet Özcan, Umberto Galderisi
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Senotherapeutics are new drugs that can modulate senescence phenomena within tissues and reduce the onset of age-related pathologies. Senotherapeutics are divided into senolytics and senomorphics. The senolytics selectively kill senescent cells, whil
Externí odkaz:
https://doaj.org/article/c93deb9e16c047d7a7c377276f18e534
Autor:
Girolamo Di Maio, Nicola Alessio, Gianfranco Peluso, Silverio Perrotta, Marcellino Monda, Giovanni Di Bernardo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12151 (2022)
Two different types of adipose depots can be observed in mammals: white adipose tissue (WAT) and brown adipose tissue (BAT). The primary role of WAT is to deposit surplus energy in the form of triglycerides, along with many metabolic and hormonal act
Externí odkaz:
https://doaj.org/article/c209c5c5ce5041f782a3cf93e954a96a
Autor:
Tiziana Squillaro, Servet Özcan, Nicola Alessio, Mustafa Burak Acar, Giovanni Di Bernardo, Mariarosa Ab Melone, Gianfranco Peluso, Umberto Galderisi
Publikováno v:
Erciyes Medical Journal, Vol 41, Iss 2, Pp 135-140 (2019)
Objective: In the present study we aim to evaluate whether some of the proteins previously identified in the secretome of senescent bone marrow (BM)- and adipose (A)-mesenchymal stromal cells (MSCs) could be involved in regulation of senescence pheno
Externí odkaz:
https://doaj.org/article/e6f024a425294b5f985134d8723e792e
Autor:
Nicola Alessio, Antonietta Stellavato, Domenico Aprile, Donatella Cimini, Valentina Vassallo, Giovanni Di Bernardo, Umberto Galderisi, Chiara Schiraldi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mesenchymal stromal cells (MSCs) are currently used for cartilage cell therapy because of their well proven capacity to differentiate in chondrocytes. The advantage of MSC-based therapy is the possibility of producing a high number of chondrocytes fo
Externí odkaz:
https://doaj.org/article/54354d1678f74e7b8b812e8ac9b81518