Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Giovanni Ciarrocchi"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:2766-2772
All known DNA ligases catalyze the formation of a phosphodiester linkage between adjacent termini in double-stranded DNA via very similar mechanisms. The ligase family can, however, be divided into two classes: eubacterial ligases, which require NAD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23dcd2b70d0c4ed4bed031bf87d484aa
https://doi.org/10.1128/aac.43.11.2766
https://doi.org/10.1128/aac.43.11.2766
Autor:
Giovanni Ciarrocchi, Federico Focher, R. Manservigi, Antonio Carcuro, Silvio Spadari, Anna Garbesi, Stefano Iotti, Giovanni Maga, Federico Arcamone, Massimo L. Capobianco, Francesco Paolo Colonna
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652742876ddd24b2c5b1283c7eb2a78c
https://doi.org/10.1002/chin.199321252
https://doi.org/10.1002/chin.199321252
Publikováno v:
European Journal of Biochemistry. 203:53-58
A novel form of rat liver DNA ligase (molecular mass 100 kDa) can be differentiated from DNA ligase I by several biochemical parameters. It is a more heat-labile enzyme and unable to join blunt-ended DNA, even in the presence of poly(ethylene glycol)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e418039abd6e747cb874a94b39a783c
https://doi.org/10.1111/j.1432-1033.1992.tb19826.x
https://doi.org/10.1111/j.1432-1033.1992.tb19826.x
Publikováno v:
Scopus-Elsevier
A total of 19 anthracycline derivatives were tested for their ability to interfere in vitro with the action of the human replicative DNA ligase. Only those with the sugar devoid of unmodified amino groups or with large configurational modifications w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5808c2d91ef6fab0af8c8d57aaf79b09
https://doi.org/10.1042/bj2790141
https://doi.org/10.1042/bj2790141
Autor:
Alessandra Montecucco, Guido Pedrali-Noy, Silvio Spadari, Giovanni Ciarrocchi, Marta Lestingi
Publikováno v:
Scopus-Elsevier
Bacteriophage-T4 and human type I DNA ligases were found capable of self-adenylating upon exposure to both ribo- and deoxyribo-[alpha-35S]thio-ATP. However, the joining reaction does not take place in the presence of the deoxyribotriphosphates. Enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52fddaafd82cbf0c9844f48a361c1ee
https://doi.org/10.1042/bj2710265
https://doi.org/10.1042/bj2710265
Autor:
Giorgio Palù, Cristina Parolin, Manlio Palumbo, Guido Pedrali-Noy, Giovanni Ciarrocchi, Alessandra Montecucco, S. Valisena
Publikováno v:
FEMS Microbiology Letters. 68:341-346
The activity of DAPI, on a number of DNA-directed enzymes involved in DNA topology, transcription, replication and repair, is reported in this paper. DAPI was always more inhibitory than ethidium bromide, in particular against RNA polymerase and DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d291a545fb2ce1d4905735c454fd8f97
https://doi.org/10.1111/j.1574-6968.1990.tb13962.x
https://doi.org/10.1111/j.1574-6968.1990.tb13962.x
Autor:
Marta Lestingi, Alessandra Montecucco, Giovanni Ciarrocchi, Guido Pedrali-Noy, Silvio Spadari
Publikováno v:
Scopus-Elsevier
A number of DNA intercalating and externally binding drugs have been found to inhibit nick sealing, cohesive and blunt end ligation, AMP-dependent DNA topoisomerization and EDTA-induced DNA nicking mediated by bacteriophage T4 DNA ligase. The inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59744e5a9e06cb9bdc25c46d47d18547
https://doi.org/10.1042/bj2660379
https://doi.org/10.1042/bj2660379
Autor:
Catherine Hildebrand, George E. Wright, Silvio Spadari, Joseph Gambino, Giovanni Ciarrocchi, Federico Focher, Daniele Sandoli
Publikováno v:
Scopus-Elsevier
A series of N2-phenylguanines was synthesized and tested for inhibition of the thymidine kinases encoded by Herpes simplex viruses type 1 and type 2. Compounds with hydrophobic, electron-attracting groups in the meta position of the phenyl ring such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19521bd0f591492f0abd2ae779ea30b
https://doi.org/10.1021/jm00163a033
https://doi.org/10.1021/jm00163a033
Autor:
Giovanni Ciarrocchi, Leann Tilley
Publikováno v:
Emerging Therapeutic Targets. 2:39-41
(1998). Specific inhibition of eubacterial DNA ligase. Emerging Therapeutic Targets: Vol. 2, No. 1, pp. 39-41.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::639b45598e08b6420da5b32a9e72e196
https://doi.org/10.1517/14728222.2.1.39
https://doi.org/10.1517/14728222.2.1.39
Autor:
Giuseppe Biamonti, Giovanni Ciarrocchi, Antonello Villa, Ivana Scovassi, Alessandra Montecucco, Claudia Negri, Rossella Rossi
The recruitment of DNA ligase I to replication foci in S phase depends on a replication factory targeting sequence that also mediates the interaction with proliferating cell nuclear antigen (PCNA) in vitro . By exploiting a monoclonal antibody direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bfed41bbdc87c2532687ef78d7826f
http://hdl.handle.net/10281/18444
http://hdl.handle.net/10281/18444
