Zobrazeno 1 - 10
of 494
pro vyhledávání: '"Giovanni Blandino"'
Autor:
Valeria Canu, Sebastiano Vaccarella, Andrea Sacconi, Claudio Pulito, Frauke Goeman, Matteo Pallocca, Daniela Rutigliano, Sima Lev, Sabrina Strano, Giovanni Blandino
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-15 (2024)
Abstract Triple negative breast cancer (TNBC) is an aggressive disease which currently has no effective therapeutic targets and prominent biomarkers. The Sperm Associated antigen 5 (SPAG5) is a mitotic spindle associated protein with oncogenic functi
Externí odkaz:
https://doaj.org/article/5435e8c8e2ce4120ac48f56e3d60ac59
Autor:
Valentina Piastra, Federica Ganci, Andrea Sacconi, Angelina Pranteda, Matteo Allegretti, Roberta Bernardini, Martina Serra, Barbara Lupo, Emanuela Dell’Aquila, Gianluigi Ferretti, Edoardo Pescarmona, Armando Bartolazzi, Giovanni Blandino, Livio Trusolino, Gianluca Bossi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Colorectal cancer (CRC) is the third most common type of cancer and the second leading cause of cancer-related deaths worldwide, with a survival rate near to 10% when diagnosed at an advanced stage. Hence, the identification of ne
Externí odkaz:
https://doaj.org/article/536b2932e0ac43d4922bd78ef035bbe1
Autor:
Flaminia Campo, Oreste Iocca, Francesca Paolini, Valentina Manciocco, Silvia Moretto, Armando De Virgilio, Claudio Moretti, Antonello Vidiri, Aldo Venuti, Paolo Bossi, Giovanni Blandino, Raul Pellini
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-10 (2024)
Abstract Background Human papilloma virus (HPV) related cancers of the oropharynx are rapidly increasing in incidence and may soon represent the majority of all head and neck cancers. Improved monitoring and surveillance methods are thus an urgent ne
Externí odkaz:
https://doaj.org/article/c45d9903896b458481bb9a783a051808
Autor:
Carla Mottini, Francesca Romana Auciello, Isabella Manni, Christian Pilarsky, Damiano Caputo, Giulio Caracciolo, Alessandro Rossetta, Elena Di Gennaro, Alfredo Budillon, Giovanni Blandino, Maria Serena Roca, Giulia Piaggio
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Pancreatic cancer (PC) is a clinically challenging tumor to combat due to its advanced stage at diagnosis as well as its resistance to currently available therapies. The absence of early symptoms and known detectable biomarkers renders this
Externí odkaz:
https://doaj.org/article/1d2f16cebe2f4958af9a0b0d71aaa906
The lncRNAMALAT1-WTAP axis: a novel layer of EMT regulation in hypoxic triple-negative breast cancer
Autor:
Martina Dragonetti, Chiara Turco, Anna Benedetti, Frauke Goeman, Mattia Forcato, Stefano Scalera, Matteo Allegretti, Gabriella Esposito, Francesco Fazi, Giovanni Blandino, Sara Donzelli, Giulia Fontemaggi
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Early metastatic disease development is one characteristic that defines triple-negative breast cancer (TNBC) as the most aggressive breast cancer (BC) subtype. Numerous studies have identified long non-coding RNAs (lncRNA) as critical player
Externí odkaz:
https://doaj.org/article/e879368ac3de4165a4efafc2ff8ca490
Autor:
Claudio Pulito, Federica Mori, Andrea Sacconi, Frauke Goeman, Maria Ferraiuolo, Patrizia Pasanisi, Carlo Campagnoli, Franco Berrino, Maurizio Fanciulli, Rebecca J. Ford, Massimo Levrero, Natalia Pediconi, Ludovica Ciuffreda, Michele Milella, Gregory R. Steinberg, Mario Cioce, Paola Muti, Sabrina Strano, Giovanni Blandino
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-8 (2024)
Externí odkaz:
https://doaj.org/article/501e7d37afcc4aa583a480148d920162
Autor:
Federica Ganci, Matteo Allegretti, Carlotta Frascolla, Francesca Spinella, Francesca Rollo, Andrea Sacconi, Pascale De Valentina, Alina Catalina Palcau, Valentina Manciocco, Mariavittoria Vescovo, Ettore Cotroneo, Francesca Blandino, Maria Benevolo, Renato Covello, Paola Muti, Sabrina Strano, Antonello Vidiri, Giulia Fontemaggi, Raul Pellini, Giovanni Blandino
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-5 (2024)
Abstract Locoregional recurrences represent a frequently unexpected problem in head and neck squamous cell carcinoma (HNSCC). Relapse often (10–30%) occurs in patients with histologically negative resection margins (RMs), probably due to residual t
Externí odkaz:
https://doaj.org/article/4aec13763f344428a3a4e758c3570cc9
Autor:
Giulia Schiavoni, Beatrice Messina, Stefano Scalera, Lorenzo Memeo, Cristina Colarossi, Marzia Mare, Giovanni Blandino, Gennaro Ciliberto, Giulia Bon, Marcello Maugeri-Saccà
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background First identified in Drosophila melanogaster, the Hippo pathway is considered a major regulatory cascade controlling tissue homeostasis and organ development. Hippo signaling components include kinases whose activity regulates YAP
Externí odkaz:
https://doaj.org/article/c14aefa5d7e340788e63b87dea7ef150
Autor:
Anna Benedetti, Chiara Turco, Enzo Gallo, Theodora Daralioti, Andrea Sacconi, Claudio Pulito, Sara Donzelli, Claudia Tito, Martina Dragonetti, Letizia Perracchio, Giovanni Blandino, Francesco Fazi, Giulia Fontemaggi
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-14 (2024)
Abstract Understanding the mechanisms of breast cancer cell communication underlying cell spreading and metastasis formation is fundamental for developing new therapies. ID4 is a proto-oncogene overexpressed in the basal-like subtype of triple-negati
Externí odkaz:
https://doaj.org/article/6a428de02f4a4444a6b19df3f26c4bbb
Autor:
Andrea Sacconi, Paola Muti, Claudio Pulito, Giulia Urbani, Matteo Allegretti, Raul Pellini, Nikolay Mehterov, Uri Ben-David, Sabrina Strano, Paolo Bossi, Giovanni Blandino
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background Immune checkpoint inhibitors (ICIs) are a therapeutic strategy for various cancers although only a subset of patients respond to the therapy. Identifying patients more prone to respond to ICIs may increase the therapeutic benefit
Externí odkaz:
https://doaj.org/article/d78903983c76433080b685a34a6e160d