Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Giovanni Benard"'
Publikováno v:
Neurobiology of Disease, Vol 90, Iss , Pp 1-2 (2016)
Externí odkaz:
https://doaj.org/article/1fbe320a8015406b93010922d22960ba
Autor:
Giovanni Benard, Khyati Bhatelia, Dhanendra Tomar, Paresh Prajapati, Rochika Singh, Sripada Lakshmi, Kritarth Singh, Rajesh Singh, Milton Roy, Julie Lavie
Publikováno v:
Free Radical Biology and Medicine. 89:1036-1048
The emerging evidences suggest that posttranslational modification of target protein by ubiquitin (Ub) not only regulate its turnover through ubiquitin proteasome system (UPS) but is a critical regulator of various signaling pathways. During ubiquiti
Autor:
Rodrigue Rossignol, Isabelle Coupry, Michel Koenig, Magalie Barth, Cyril Goizet, Nadège Bellance, Dominique Bonneau, Agnès Guichet, Diana Rodriguez, Christelle M. Durand, Nada Houcinat, Julie Bouron, Sébastien Moutton, Julie Lavie, Sandra Chantot-Bastaraud, Julie Pilliod, Alexandra Durr, Karine Nguyen, Alexis Brice, Didier Hannequin, Giovanni Benard, Mathieu Anheim, Perrine Charles, Christel Thauvin-Robinet, Alexandra Afenjar, Elise Maurat, Guillaume Fromager, Patrick Berquin, Didier Lacombe, Caroline Rooryck, Dan Milea, Sylvie Forlani, Philippe Convers, Elisabeth Maillart, Christophe Verny, Stéphanie Valence, Julien Van-Gils, Fanny Mochel, Christophe Hubert, Giovanni Stevanin, Lucie Guyant-Maréchal, Lydie Burglen, Gaetan Lesca
Publikováno v:
Annals of Neurology. 78:871-886
Objective Autosomal recessive spastic ataxia of Charlevoix–Saguenay (ARSACS) is caused by mutations in the SACS gene. SACS encodes sacsin, a protein whose function remains unknown, despite the description of numerous protein domains and the recent
Autor:
François Rivier, Alexandra Durr, Nicolas Pietrancosta, Guja Astrea, Laetitia Fouillen, Cyril Goizet, Giovanni Stevanin, Patrick J. Babin, Claire Pujol, Khalid H. El-Hachimi, Jean-Luc Boucher, Stéphanie Jacqueré, Isabelle Coupry, Filippo M. Santorelli, Giovanni Benard, Daniel Mansuy, Guillaume Banneau, Alessandra Tessa, Christelle M Durand, Laura Dhers, Laure Raymond, Frédéric Darios, Didier Lacombe, Christelle Tesson
Publikováno v:
Human Mutation
Human Mutation, Wiley, 2018, 39 (1), pp.140-151. ⟨10.1002/humu.23359⟩
Human Mutation, Wiley, 2018, 39 (1), pp.140-151. ⟨10.1002/humu.23359⟩
International audience; Hereditary spastic paraplegia (HSP) is an inherited disorder of the central nervous system mainly characterized by gradual spasticity and weakness of the lower limbs. SPG56 is a rare autosomal recessive early onset complicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcaf5cf4ad05aa1f73a203477b1ce953
http://hdl.handle.net/20.500.12278/111725
http://hdl.handle.net/20.500.12278/111725
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1853(10):2812-2821
Mitochondria are intracellular power plants that feed most eukaryotic cells with the ATP produced by the oxidative phosphorylation (OXPHOS). Mitochondrial energy production is controlled by many regulatory mechanisms. The control of mitochondrial mas
Autor:
Ana Madalina Ion, Jean-William Dupuy, Didier Lacombe, Su Melser, Harmony De Belvalet, Sessinou Sonon, Elodie Dumon, Claude Lalou, Julie Lavie, Giovanni Benard
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2018, 23 (10), pp.2852-2863. ⟨10.1016/j.celrep.2018.05.013⟩
Cell Reports, Elsevier Inc, 2018, 23 (10), pp.2852-2863. ⟨10.1016/j.celrep.2018.05.013⟩
The ubiquitin proteasome system (UPS) regulates many cellular functions by degrading key proteins. Notably, the role of UPS in regulating mitochondrial metabolic functions is unclear. Here, we show that ubiquitination occurs in different mitochondria
Autor:
Giovanni Marsicano, Pedro Grandes, Rodrigue Rossignol, Pier Vincenzo Piazza, Leire Reguero, Nagore Puente, Giovanni Benard, Beat Lutz, Francis Chaouloff, Etienne Hebert-Chatelain
Publikováno v:
Molecular Metabolism
Brain mitochondrial activity is centrally involved in the central control of energy balance. When studying mitochondrial functions in the brain, however, discrepant results might be obtained, depending on the experimental approaches. For instance, im
Autor:
Christelle Tesson, Roman Serrat, Jean-William Dupuy, Nadège Bellance, Giovanni Stevanin, Julie Lavie, Rodrigue Rossignol, Cyril Goizet, Giovanni Benard, Alexandra Durr, Isabelle Coupry, Alexis Brice, Frédéric Darios, Didier Lacombe, Gilles Courtand
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2017, pp.ddw425. ⟨10.1093/hmg/ddw425⟩
Human Molecular Genetics, 2017, pp.ddw425. ⟨10.1093/hmg/ddw425⟩
Human Molecular Genetics, Oxford University Press (OUP), 2017, pp.ddw425. ⟨10.1093/hmg/ddw425⟩
Human Molecular Genetics, 2017, pp.ddw425. ⟨10.1093/hmg/ddw425⟩
Hereditary spastic paraplegia, SPG31, is a rare neurological disorder caused by mutations in REEP1 gene encoding the microtubule-interacting protein, REEP1. The mechanism by which REEP1-dependent processes are linked with the disease is unclear. REEP
Autor:
Gabriel Barreda-Gómez, Leire Reguero, Tifany Desprez, Marjorie Varilh, Jean-William Dupuy, Geoffrey Terral, Filippo Drago, Pedro Grandes, Roman Serrat, Michelangelo Colavita, Wilfrid Mazier, Nagore Puente, Giovanni Marsicano, M. Dolores García-Fernández, Edgar Soria-Gomez, Arnau Busquets-Garcia, Giovanni Benard, Antonio C Pagano Zottola, Anna Delamarre, Luigi Bellocchio, Maria-Luz Lopez-Rodriguez, Peggy Vincent, Izaskun Elezgarai, Daniela Cota, Federico Massa, Etienne Hebert-Chatelain, Astrid Cannich, Laurie M. Robin
Publikováno v:
Nature
Nature, Nature Publishing Group, 2016, 539 (7630), pp.555-559. ⟨10.1038/nature20127⟩
Nature, Nature Publishing Group, 2016, 539 (7630), pp.555-559. ⟨10.1038/nature20127⟩
Cellular activity in the brain depends on the high energetic support provided by mitochondria, the cell organelles which use energy sources to generate ATP. Acute cannabinoid intoxication induces amnesia in humans and animals, and the activation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9ef566ada05944e7c43bee1ce3ed5c
https://hal.archives-ouvertes.fr/hal-02353802
https://hal.archives-ouvertes.fr/hal-02353802
Autor:
Sarah Dubreucq, Giovanni Marsicano, Giovanni Benard, Isabelle Matias, Francis Chaouloff, Edgar Soria-Gomez, Laurent Groc, Dusan Bartsch, Audrey Durand, Elodie Richard, Federico Massa, Aya Wadleigh, François Georges, Christelle Glangetas
Publikováno v:
Biological Psychiatry
Biological Psychiatry, Elsevier, 2013, 73 (9), pp.895-903. ⟨10.1016/j.biopsych.2012.10.025⟩
Biological Psychiatry; Vol 73
Biological Psychiatry, Elsevier, 2013, 73 (9), pp.895-903. ⟨10.1016/j.biopsych.2012.10.025⟩
Biological Psychiatry; Vol 73
Background We have shown that the endogenous stimulation of cannabinoid type-1 (CB 1 ) receptors is a prerequisite for voluntary running in mice, but the precise mechanisms through which the endocannabinoid system exerts a tonic control on running pe