Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Giovanni, Pacini"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The aim of this study was to develop a dynamic model-based approach to separately quantify the exogenous and endogenous contributions to total plasma insulin concentration and to apply it to assess the effects of inhaled-insulin administrati
Externí odkaz:
https://doaj.org/article/996d6dde823e49adacb9410f7e77c09b
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract It has not been elucidated whether incretins affect insulin clearance in type 2 diabetes (T2D). We aimed exploring possible associations between insulin clearance and endogenously secreted or exogenously administered incretins in T2D patient
Externí odkaz:
https://doaj.org/article/a0ab9c0d6a504560aaa3669a917fa54a
Autor:
Johanna Maria Brix, Andrea Tura, Carsten Thilo Herz, Astrid Feder, Eva-Christina Krzizek, Verena Parzer, Giovanni Pacini, Bernhard Ludvik
Publikováno v:
Obesity Facts, Vol 14, Iss 5, Pp 510-519 (2021)
Introduction: Cortisol is involved in the regulation of gluconeogenesis and glucose utilization. In morbid obesity (MO), the association of cortisol excretion with metabolic parameters is not well-characterized. In our study, we evaluated cortisol ex
Externí odkaz:
https://doaj.org/article/2ae3475f495f4ce788f212a8d92cdae6
Autor:
Pierre Theurey, Carole Thang, Valdis Pirags, Andrea Mari, Giovanni Pacini, Sébastien Bolze, Sophie Hallakou‐Bozec, Pascale Fouqueray
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 5, Iss 6, Pp n/a-n/a (2022)
Abstract Introduction The aim of the present study was to evaluate the effect of 18‐week monotherapy with imeglimin on glucose tolerance and on insulin secretion/sensitivity in type 2 diabetic (T2D) patients. Methods The study was an 18‐week, dou
Externí odkaz:
https://doaj.org/article/c168b0344ab6477f8ad30762fcf79386
Autor:
Micaela Morettini, Maria Concetta Palumbo, Christian Göbl, Laura Burattini, Yanislava Karusheva, Michael Roden, Giovanni Pacini, Andrea Tura
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Amino acids (AAs) are well known to be involved in the regulation of glucose metabolism and, in particular, of insulin secretion. However, the effects of different AAs on insulin release and kinetics have not been completely elucidated. The aim of th
Externí odkaz:
https://doaj.org/article/237a479911d04e75a6c74ed6044b24b3
Autor:
Daniela Vejrazkova, Marketa Vankova, Josef Vcelak, Hana Krejci, Katerina Anderlova, Andrea Tura, Giovanni Pacini, Alena Sumova, Martin Sladek, Bela Bendlova
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundThe MTNR1B gene encodes a receptor for melatonin, a hormone regulating biorhythms. Disruptions in biorhythms contribute to the development of type 2 diabetes mellitus (T2DM). Genetic studies suggest that variability in the MTNR1B gene affec
Externí odkaz:
https://doaj.org/article/ea7cf882ea6c4dbf966b6b754fb8266d
Autor:
Bo Ahrén, Giovanni Pacini
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 5, Pp 675-685 (2021)
Abstract Besides insulin‐mediated transport of glucose into the cells, an important role is also played by the non‐insulin‐mediated transport. This latter process is called glucose effectiveness (acronym SG), which is estimated by modeling of g
Externí odkaz:
https://doaj.org/article/e61653077b4a4f9199135797b3dd2507
Autor:
Micaela Morettini, Carlo Castriota, Christian Göbl, Alexandra Kautzky-Willer, Giovanni Pacini, Laura Burattini, Andrea Tura
Publikováno v:
Diabetes & Metabolism Journal, Vol 44, Iss 2, Pp 286-294 (2020)
BackgroundThis study aimed to design a simple surrogate marker (i.e., predictor) of the minimal model glucose effectiveness (SG), namely calculated SG (CSG), from a short insulin-modified intravenous glucose tolerance test (IM-IVGTT), and then to app
Externí odkaz:
https://doaj.org/article/831dc6616222496b90609cb1816f67b7
Autor:
Micaela Morettini, Christian Göbl, Alexandra Kautzky-Willer, Giovanni Pacini, Andrea Tura, Laura Burattini
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 2, Pp 1604-1615 (2020)
Women with a previous history of gestational diabetes mellitus (GDM) have increased risk of developing GDM in future pregnancies (i.e. recurrent GDM) and also Type 2 Diabetes (T2D). Insulin clearance represents one of the processes regulating glucose
Externí odkaz:
https://doaj.org/article/bfc35a992a6b4fe1a92bea9ee61a7ef9
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b1393b650ccc4bc78767ca1a1156290f