Zobrazeno 1 - 10
of 444
pro vyhledávání: '"Giovanna T"'
Autor:
Kathryn Dubowski, Giovanna T. Braganza, Anne Bozack, Elena Colicino, Nicholas DeFelice, Laura McGuinn, Duncan Maru, Alison G. Lee
Publikováno v:
Annals of Medicine, Vol 55, Iss 1, Pp 12-23 (2023)
AbstractBackground We have an incomplete understanding of COVID-19 characteristics at hospital presentation and whether underlying subphenotypes are associated with clinical outcomes and therapeutic responses.Methods For this cross-sectional study, w
Externí odkaz:
https://doaj.org/article/05d0f86fd4d146b38ea1cb4d68d3d30c
Autor:
Jinyang Cai, Sheeba Jacob, Richard Kurupi, Krista M. Dalton, Colin Coon, Patricia Greninger, Regina K. Egan, Giovanna T. Stein, Ellen Murchie, Joseph McClanaghan, Yuta Adachi, Kentaro Hirade, Mikhail Dozmorov, John Glod, Sosipatros A. Boikos, Hiromichi Ebi, Huaixiang Hao, Giordano Caponigro, Cyril H. Benes, Anthony C. Faber
Publikováno v:
Cell Reports, Vol 40, Iss 4, Pp 111095- (2022)
Summary: Reoccurring/high-risk neuroblastoma (NB) tumors have the enrichment of non-RAS/RAF mutations along the mitogen-activated protein kinase (MAPK) signaling pathway, suggesting that activation of MEK/ERK is critical for their survival. However,
Externí odkaz:
https://doaj.org/article/3169f73446bb4502b9e30b3d5f9b0105
Autor:
Noura S. Abul-Husn, Emily R. Soper, Giovanna T. Braganza, Jessica E. Rodriguez, Natasha Zeid, Sinead Cullina, Dean Bobo, Arden Moscati, Amanda Merkelson, Ruth J. F. Loos, Judy H. Cho, Gillian M. Belbin, Sabrina A. Suckiel, Eimear E. Kenny
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background Population-based genomic screening has the predicted ability to reduce morbidity and mortality associated with medically actionable conditions. However, much research is needed to develop standards for genomic screening and to und
Externí odkaz:
https://doaj.org/article/622c943747f5441b88bd76675c60c7ad
Autor:
Tina L. Yuan, Arnaud Amzallag, Rachel Bagni, Ming Yi, Shervin Afghani, William Burgan, Nicole Fer, Leslie A. Strathern, Katie Powell, Brian Smith, Andrew M. Waters, David Drubin, Ty Thomson, Rosy Liao, Patricia Greninger, Giovanna T. Stein, Ellen Murchie, Eliane Cortez, Regina K. Egan, Lauren Procter, Matthew Bess, Kwong Tai Cheng, Chih-Shia Lee, Liam Changwoo Lee, Christof Fellmann, Robert Stephens, Ji Luo, Scott W. Lowe, Cyril H. Benes, Frank McCormick
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1889-1902 (2018)
Summary: KRAS can bind numerous effector proteins, which activate different downstream signaling events. The best known are RAF, phosphatidylinositide (PI)-3′ kinase, and RalGDS families, but many additional direct and indirect effectors have been
Externí odkaz:
https://doaj.org/article/b9acf930ce7f49cbbf8886d56ca37592
Autor:
Byunghee Yoo, Patricia Greninger, Giovanna T Stein, Regina K Egan, Joseph McClanaghan, Anna Moore, Cyril H Benes, Zdravka Medarova
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201046 (2018)
Since microRNAs (miRNAs, miRs) have been implicated in oncogenesis, many of them have been identified as therapeutic targets. Previously we have demonstrated that miRNA-10b acts as a master regulator of the viability of metastatic tumor cells and rep
Externí odkaz:
https://doaj.org/article/7d4e07a6112548db9914389c72aecba7
Autor:
Dalton, Krista M., Lochmann, Timothy L., Floros, Konstantinos V., Calbert, Marissa L., Kurupi, Richard, Stein, Giovanna T., McClanaghan, Joseph, Murchie, Ellen, Egan, Regina K., Greninger, Patricia, Dozmorov, Mikhail, Ramamoorthy, Sivapriya, Puchalapalli, Madhavi, Hu, Bin, Shock, Lisa, Koblinski, Jennifer, Glod, John, Boikos, Sosipatros A., Benes, Cyril H., Faber, Anthony C.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar . 118(13), 1-12.
Externí odkaz:
https://www.jstor.org/stable/27039780
Autor:
Matteussi, Giovanna T, Pereira, Julia GD, Rocha, Maille FN, Maranhão, Olga BV, Janson, Guilherme, da Silva, Ricardo HA
Publikováno v:
In Forensic Imaging March 2022 28
Autor:
Aguiar, Danilo R.D. *, da Costa, Gabriella Nunes, Simões, Giovanna T. Camargo, Figueiredo, Adelson Martins
Publikováno v:
In Environmental Science and Policy October 2021 124:542-552
Akademický článek
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Autor:
Sabrina A. Suckiel, Giovanna T. Braganza, Karla López Aguiñiga, Jacqueline A. Odgis, Katherine E. Bonini, Eimear E. Kenny, Jada G. Hamilton, Noura S. Abul-Husn
Publikováno v:
Genetics in Medicine. 24:1217-1226
As polygenic risk scores (PRS) emerge as promising tools to inform clinical care, there is a pressing need for patient-centered evidence to guide their implementation, particularly in diverse populations. Here, we conducted in-depth interviews of div