Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Giovanna Pannuzzo"'
Autor:
Mariarita Barone, Giovanna Pannuzzo, Andrea Santagati, Alfio Catalfo, Guido De Guidi, Venera Cardile
Publikováno v:
Molecules, Vol 19, Iss 5, Pp 6106-6122 (2014)
The aims of this study were: (i) to explore the structure-activity relationship of some new anti-inflammatory benzothieno[3,2-d]pyrimidin-4-one sulphonamide thio-derivatives 1–11; and (ii) to evaluate the possibility of using the most active compou
Externí odkaz:
https://doaj.org/article/fe254f6598df430e8f212cc8f0cca0ee
Publikováno v:
Cells, Vol 7, Iss 11, p 197 (2018)
The development in digital screen technology has exponentially increased in the last decades, and many of today’s electronic devices use light-emitting diode (LED) technology producing very strong blue light (BL) waves. Long-term exposure at LED-BL
Externí odkaz:
https://doaj.org/article/165492432a6c43b39faf88e7ad01de61
Autor:
Lorenza Vantaggiato, Enxhi Shaba, Alfonso Carleo, Daiana Bezzini, Giovanna Pannuzzo, Alice Luddi, Paola Piomboni, Luca Bini, Laura Bianchi
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13537
Krabbe disease (KD) is a rare autosomal recessive disorder caused by mutations in the galactocerebrosidase gene (GALC). Defective GALC causes aberrant metabolism of galactolipids present almost exclusively in myelin, with consequent demyelinization a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7951acecd7b37268160c7941f6ccec0c
https://pubmed.ncbi.nlm.nih.gov/36362324
https://pubmed.ncbi.nlm.nih.gov/36362324
Autor:
Laura Bianchi, Giovanna Pannuzzo, Claudia Landi, Alice Luddi, Valentina Pavone, Paola Piomboni, Luca Bini
Publikováno v:
Journal of Neuroscience Research. 98:718-733
In Krabbe disease, a mutation in GALC gene causes widespread demyelination determining cell death by apoptosis, mainly in oligodendrocytes and Schwann cells. Less is known on the molecular mechanisms induced by this deficiency. Here, we report an imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9256de4e2168d369ea5db7dc2afc321
https://doi.org/10.1002/jnr.24558
https://doi.org/10.1002/jnr.24558
Autor:
Adriana Carol Eleonora Graziano, Emanuele Longo, Andrea Santagati, Ettore Salemi, Venera Cardile, Rosanna Avola, Giovanna Pannuzzo
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 45:952-960
This study reports the synthesis, molecular docking and biological evaluation of eight (5-8 and 5a-8a) newly synthesized thieno-pyrimidinone methanesulphonamide thio-derivatives. The synthetic route used to prepare the new isomers thioaryl and thio-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25bc6701f4b979c74d6760820815baf
https://doi.org/10.1111/1440-1681.12962
https://doi.org/10.1111/1440-1681.12962
Autor:
Giovanna Pannuzzo, Jetty Chung-Yung Lee, Silvia Leoncini, Joussef Hayek, Camille Oger, Alessio Cortelazzo, Adriana Carol Eleonora Graziano, Cinzia Signorini, Claudio De Felice, Venera Cardile, Thierry Durand, Jean-Marie Galano
Publikováno v:
Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2019, 139, pp.46-54. ⟨10.1016/j.freeradbiomed.2019.05.014⟩
Free Radical Biology and Medicine, Elsevier, 2019, 139, pp.46-54. ⟨10.1016/j.freeradbiomed.2019.05.014⟩
International audience; Krabbe disease (KD) is a rare and devastating pediatric leukodystrophy caused by mutations in the galactocerebrosidase (GALC) gene. The disease leads to impaired myelin formation and extensive myelin damage in the brain. Oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234dd0baca48e6795234f478a6eb6660
https://hal.archives-ouvertes.fr/hal-02613765/document
https://hal.archives-ouvertes.fr/hal-02613765/document
Autor:
Filippo Drago, Adriana Carol Eleonora Graziano, Giovanna Pannuzzo, Venera Cardile, Rosanna Avola
Publikováno v:
Acta neurologica ScandinavicaREFERENCES. 140(5)
OBJECTIVES Globoid cell leukodystrophy or Krabbe disease is an autosomal recessive lysosomal storage disorder characterized by a deficiency in galactosylceramidase (GALC) which hydrolyses galactosylceramide and galactosylsphingosine (psychosine). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe2b95a202ea17ef5062877683d19d5
https://pubmed.ncbi.nlm.nih.gov/31350907
https://pubmed.ncbi.nlm.nih.gov/31350907
Autor:
Venera Cardile, Martina Pannuzzo, Rosanna Avola, Marcelo F. Masman, Adriana Carol Eleonora Graziano, Giovanna Pannuzzo
Publikováno v:
Journal of Neuroscience Research. 94:1318-1326
Krabbe's disease is a neurodegenerative disorder caused by deficiency of galactocerebrosidase activity that affects the myelin sheath of the nervous system, involving dysfunctional metabolism of sphingolipids. It has no cure. Because substrate inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::278568280fa7dea8209bfbaf58bbaa63
https://doi.org/10.1002/jnr.23761
https://doi.org/10.1002/jnr.23761
Publikováno v:
Journal of Neuroscience Research. 94:1220-1230
Krabbe's disease (KD) is an autosomal recessive, neurodegenerative disorder. It is classified among the lysosomal storage diseases (LSDs). It was first described in , but the genetic defect for the galactocerebrosidase (GALC) gene was not discovered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2545cceb8644d48201aa9e979182e194
https://doi.org/10.1002/jnr.23755
https://doi.org/10.1002/jnr.23755
Publikováno v:
Cells, Vol 7, Iss 11, p 197 (2018)
Cells
Volume 7
Issue 11
Cells
Volume 7
Issue 11
The development in digital screen technology has exponentially increased in the last decades, and many of today&rsquo
s electronic devices use light-emitting diode (LED) technology producing very strong blue light (BL) waves. Long-term exposure
s electronic devices use light-emitting diode (LED) technology producing very strong blue light (BL) waves. Long-term exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8467a2df8f21633c815d43ed908b594
https://www.mdpi.com/2073-4409/7/11/197
https://www.mdpi.com/2073-4409/7/11/197