Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Giovanna Murari"'
Publikováno v:
Cellular and Molecular Life Sciences (CMLS). 59:2172-2183
In this study we examined agonist-induced internalization of the cloned human nociceptin receptor (hNOP) expressed in CHOK1 cells. Internalization was proven by receptor binding assay on viable cells and confocal microscopy. The agonists nociceptin/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbf7943b696684b8b0f4a1f793bb500
https://doi.org/10.1007/s000180200016
https://doi.org/10.1007/s000180200016
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 303:1086-1094
In a previous study we ascertained the presence of sigma1 and sigma2 recognition sites in the rabbit iris-ciliary body, an ocular structure involved in aqueous humor production and drainage. We characterized the sigma1 sites using the preferential li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e44a69d4fc58929151a84eddb5bd01a
https://doi.org/10.1124/jpet.102.040584
https://doi.org/10.1124/jpet.102.040584
Autor:
Eleonora Pistacchio, Giovanna Murari, Sergio Ferri, Paolo Govoni, Santi Spampinato, Ester Speroni, Carlo Romagnoli
Publikováno v:
European Journal of Pharmacology. 254:229-238
This study with the rat evaluated the contribution of omega-conotoxin GVIA-(omega-CgTx) and verapamil-sensitive Ca2+ channels in behavioural, antinociceptive and thermoregulatory responses to intracerebroventricular (i.c.v.) injection of [D-Ala2,NMeP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a61c5333ad1e97bcecd8c9402d96d93
https://doi.org/10.1016/0014-2999(94)90459-6
https://doi.org/10.1016/0014-2999(94)90459-6
Autor:
Santi Spampinato, Luca Gentilucci, Maria Calienni, Giovanna Murari, Giuliana Cardillo, Ahmed R. Qasem, Alessandra Tolomelli
Publikováno v:
European journal of pharmacology. 469(1-3)
We previously described a novel endomorphin-1 analogue (Tyr-L-beta-Pro-Trp-Phe-NH(2); Endo1-beta-Pro) more resistant to enzymatic hydrolysis than endomorphin-1 that acts as a mu-opioid receptor agonist. In this study we report that Endo1-beta-Pro, s.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d34e9a522d77d28558ba740bb9168b
https://pubmed.ncbi.nlm.nih.gov/12782189
https://pubmed.ncbi.nlm.nih.gov/12782189
Autor:
Michele Massimino, Giovanna Murari, Giuseppe Ronsisvalle, Agostino Marrazzo, F. Vittorio, Santi Spampinato, Orazio Prezzavento
Publikováno v:
Journal of medicinal chemistry. 45(12)
(+)-cis-N-(4-Isothiocyanatobenzyl)-N-normetazocine (BNIT) (+)-(4) was designed and synthesized as a derivative of the potent and selective sigma(1) receptor ligand (+)-cis-N-benzyl-N-normetazocine for irreversibly blocking sigma(1) binding sites. Pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea379230a803a2106cf307698d71c3a9
https://pubmed.ncbi.nlm.nih.gov/12036376
https://pubmed.ncbi.nlm.nih.gov/12036376
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 11(4)
Bile acids may play a role in the pathogenesis of intestinal inflammation by activating the signalling pathways that control cell proliferation, among other cell systems. We investigated the action of different bile acids, particularly chenodeoxychol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d46a26c9a2a1c4209f00b388a35b7970
https://pubmed.ncbi.nlm.nih.gov/11033072
https://pubmed.ncbi.nlm.nih.gov/11033072
Publikováno v:
Neuroscience letters. 273(3)
In this study we characterized calcitonin (CT) receptors in human neuroblastoma IMR 32 cells. Saturation binding assays indicated that [125I]-human CT bound with high affinity to IMR 32 cell membranes (K(d) = 253.6 pM; Bmax = 3.84 fmol/ mg protein).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9aefd2e847a43bdb3905621c6558401
https://pubmed.ncbi.nlm.nih.gov/10515185
https://pubmed.ncbi.nlm.nih.gov/10515185
Autor:
Gabriele Campana, Lucia Carboni, Santi Spampinato, Ester Speroni, Giovanna Murari, S. Cacciaguerra, Giuseppe Ronsisvalle, Pappalardo Ms
Publikováno v:
Annals of the New York Academy of Sciences. 812
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2a52660fb44bed745515d233b4e9eb
https://pubmed.ncbi.nlm.nih.gov/9186743
https://pubmed.ncbi.nlm.nih.gov/9186743
Autor:
Sergio Ferri, Giovanna Murari, Marco Canossa, Gabriele Campana, T. Bachetti, Santi Spampinato
Publikováno v:
Brain research. 580(1-2)
We measured the release of immunoreactive (ir) dynorphin (dyn) A-(1-17) and dyn B from the rat hypothalamus by an in vitro superfusion technique. The system was validated on the basis of the recovery and stability of radiolabeled peptides added to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad173e498d89aafa3ef137ce1b3fa2c
https://pubmed.ncbi.nlm.nih.gov/1354557
https://pubmed.ncbi.nlm.nih.gov/1354557
Publikováno v:
Pharmacological Research. 26:190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ba171209a45c311c22bdd4bed5c3015
https://doi.org/10.1016/1043-6618(92)91089-y
https://doi.org/10.1016/1043-6618(92)91089-y